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Chitosan-schiff base with three different ratios of para-Dimethyl aminobenzaldehyde& chitosan Schiff
base hydrogels have been prepared for controlled drug release study. The synthesized chitosan Schiff
base and chitosan Schiff base hydrogel were characterized by FT-IR, UV-Visible, SEM, analysis. Swelling
properties of the hydrogel were investigated at three different media pH (2, 7, 10). The swelling degree
varied with the pH, amount of crosslinking agent glutaraldehyde and with the amount of paraDimethylaminobenzaldehyde for the hydrogels. All hydrogels were used for controlled drug release
system. Aspirin was used as model drug, in three different buffer solution (2, 7, 10) as release media. The
rate of release of drugs in the pH2 is more
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