Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. Therefore, it is critical for researchers to understand molecular biology in greater depth. In several diseases including cancer, abnormal miRNA expression has been linked to apoptosis, proliferation, differentiation, and metastasis. Many miRNAs have been studied in relation to cancer, including miR-122, miR-223, and others. Hepatitis B and C viruses are the most important global risk factors for HCC. This study is intended to test whether serum miRNAs serve as a potential biomarker for both HCC and viral infections HBV and C. The expression of miRNA in 64 serum samples was analyzed by RT-qPCR. Compared to healthy volunteers, HCC patients' sera expressed significantly lower levels of miR-122 and miR-223. Furthermore, we compared the expression of these miRNAs between early-diagnosed HCC patients and healthy controls. There was a significant difference between miR-122 expression in HCC sera and healthy volunteers' sera (0.000 and 0.253, respectively), with a P value of <0.0001. Early diagnostic patients without treatment had completely deleted miR-122 expression levels, while those treated had slightly elevated levels. Clearly, miR-122 has been identified as a biomarker for early detection and follow-up of HCC treatment. HBV and HCV specimens expressed significantly lower levels of miRNA than normal samples with a P value of <0.0001. It is recommended that these findings be further investigated for diagnostic purposes. Further, these miRNAs are highly specific for diagnosing HCC, HBV, and HCV, making them valuable therapeutic indicators.
The energy consider generally and specifically the petroleum energy
from the prior requirement of the population and nations, and the basics of the
survival of mankind and all the challenges for the sake of continuum, so
without this energy the life of ankind being varied, so far the life is still as a
fact on the planet earth, and suppose the life may continue as the willing of
Allah ,that the events and the standards and the degree of development is still
as it is, in another word no any technical developments and no any
entertainment no transportation and also there is no demographic domination
for the whole lands belonging to Allah, certainly no way to talk more on what
we and the others knew, what is the g
There are words that are described in certain words that are not described in other words, so the relationship between two words that accompany a habit is strengthened, which leads to the emergence of a conjunction or an idiomatic expression
That art and poetic creativity is not associated with a certain time and place and that artistic inspiration is a gift from God loved to a group of individuals so that their experiences be simulated speaking to the insides of the human self and that the creativity of the artist poet lies in the purpose of what is familiar and accepted and mocked for this purpose to
Araştırmamın adı: Türkçe'de –madan, -meden Ulaç Ekinin Yazılışı ve Kullanılışıdır.
Ulaçlar, kişi ve zaman kavramı olmadan temel cümlenin yada yan cümlenin yüklemini niteleyen, cümlede genellikle zarf tümleci olarak görev yapan fiilimsilerdir. İkinci bir görevleri yardımcı fiillerle birlikte kullanılarak birleşik fiiller kurmak olan ulaçlar, cümlede bağlaç görevinde kullanılabilirler, ve birleşik cümleler kurabilirler. Bazı ulaç ekleri zarf, edat gibi kalıcı sözcük yapımında da kullanılırlar.
Bu araştırmada Orhun Türkçesi'nde başlayıp Türkiye Türkçesine kadar uzanan tarihi dönemlere ait eserlerden –m
... Show MoreFind spins educational thought in the arguments of Imam Jafar Sadiq ( peace be upon him ), which is a valid approach to every age and generation , a fact the Lord's suitable for all ages, and a natural extension of the message the sky . Here was a project of Imam Sadiq ( peace be upon him ) for the breeding of individuals and the Islamic nation in general, so it was launched search to explain features of this educational thought when Imam Jafar Sadiq ( peace be upon him )
الكوارث الطبيعية واضرارها على حياة الانسان قديمة لاتحددها فترة زمنية بعينها دون الاخرى ، انها موجودة مند الازل قدم لنا القران الكريم ، والحديث النبوي الشريف ، وكتب التاريخ والجغرافية والبلدان ، وكتب الثقافة العامة وكتب الانواء ، وبعض الكتب المستقلة في الموضوع ومنها كتاب كشف الصلصة في وصف الزلزلة للسيوطي ( ت 911هـ) نمادج لا تحصى من انواع الكوارث الطبيعية ، والتبدلات الجذرية التي حلت بالمجتمعات نتيجة لوقوع
... Show Moreالتطابق بين أجزاء الجملة في مسرحية الوصيفات لأنطونيو بويرو باييخو.
مشكلة البحث
لقد تفاقمت مشكلة تلوث البيئة في السنوات الأخيرة من العقد الأخير والعقد الأول من القرنين العشرين والحادي والعشرين على التوالي بشكل يلفت النظر. إذ انتشر الاستعمال غير العقلاني للموارد الطبيعية من مياه ملوثة وسكن غير صحي وغير ملائم وسؤ التغذية وظروف الصحة العامة الرديئة وانتشار العوادم التي تحدثها المركبات والمولدات التي انتشرت في أحياء المدن العراقية لتزوي
... Show MoreThank Allah and prayers on the Prophet Mohammed the man of truth and honest (PBUH).
The initiations in the role of Imam Ali (PBUH) is considered among the important initiations in Islamic thinking .It is considered the way to invest the conditions that the individual in the light of it can reach to make gains and achievements
This search aims to meditate Divan of Hazem Al-Qirtagni his incomplete contiguous and non-contiguous naturalizations are investigated through two interrelated sections, the first is contiguous deficient naturalization and the analysis of phonemic symmetry in the light of syntactic syntax, phonemic (partial) symmetry and semantic difference