Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. Therefore, it is critical for researchers to understand molecular biology in greater depth. In several diseases including cancer, abnormal miRNA expression has been linked to apoptosis, proliferation, differentiation, and metastasis. Many miRNAs have been studied in relation to cancer, including miR-122, miR-223, and others. Hepatitis B and C viruses are the most important global risk factors for HCC. This study is intended to test whether serum miRNAs serve as a potential biomarker for both HCC and viral infections HBV and C. The expression of miRNA in 64 serum samples was analyzed by RT-qPCR. Compared to healthy volunteers, HCC patients' sera expressed significantly lower levels of miR-122 and miR-223. Furthermore, we compared the expression of these miRNAs between early-diagnosed HCC patients and healthy controls. There was a significant difference between miR-122 expression in HCC sera and healthy volunteers' sera (0.000 and 0.253, respectively), with a P value of <0.0001. Early diagnostic patients without treatment had completely deleted miR-122 expression levels, while those treated had slightly elevated levels. Clearly, miR-122 has been identified as a biomarker for early detection and follow-up of HCC treatment. HBV and HCV specimens expressed significantly lower levels of miRNA than normal samples with a P value of <0.0001. It is recommended that these findings be further investigated for diagnostic purposes. Further, these miRNAs are highly specific for diagnosing HCC, HBV, and HCV, making them valuable therapeutic indicators.
دراسة تحليلية لترجمة المسكوكات اللغوية في الصحافة الاسبانية.
يُعنى هذا البحث بمهارة د راسة وكتابة الهمزة التي تعدّ , برغم كثرة محاولات تيسيرها من
أعقد المسائل المتعمقة بقواعد الإملاء في الكتابة العربية
The global globalization the world is experiencing has enabled international actors—states, international governmental and non-governmental organizations, such as liberation movements, international social movements, and even terrorist organizations—to use cyber power to achieve their goals. Therefore, this study discusses the impact of information power on the domestic environment of the United States.
This paper shed light on castles in Iraq through Othman reign to know their sorts , and studying planning concentrating on the nature of architecture , this is a serious trying to study and important side of military architecture in Iraq with its reasons of building them which had related with political, military , social ,and economical circumstances of country .
Land beyond the river has the attention of historians, especially travelers and geographers of its various regions under the Islamic Arab state. They antedate the social and economic aspects, including agriculture, industry and trade in their products and goods to other countries and urbanism, which we will address in our research
المنطق منهجا نقديا - دراسة في قراءة الشكل الجمالي كتاب (المنطق منهجا نقدياً – دراسة في قراءة الشكل الفني) يهتم الكتاب بدراسة التصورات المنطقية في الفنون التشكيلية وهو يقع في اربعة فصول خصص الاول منها لبيان المنهجية والفكرة العامة عن علاقة المعرفة بالقواعد الفكرية والقواعد المنطقية موضحا ذلك في (مدخل عام) وتعلق الفصل الثاني بالمفاهيم المنطقية وما كتبه علماء المنطق في عرض شامل ومكثف تناول فيه المؤلف مفهوم ال
... Show MoreWhat linguists mentioned about the infinitive and its use in the linguistic levels of speech, whether with its verb, or what was mentioned in the difference between the infinitive and the noun of the source, are matters that are related to the phenomenon of hearing in speech, a need necessitated by the nature of the linguistic law and its connection with the Arabic dialects, which proceeded in the linguistic levels to form Phenomenon inherent in the use of the source and the name of the source
This poem is regarded an important Harmonized structure in modern and Contemporary Culture to achieve aqualitative poem Comported with the other cultural structures inorder to discover the ego and aspiration in shaping distinctive voices.
The Iraqi poetry is affected tangibly by this poem because of the intellective vaccinating between Iraqi and Arab poets ingeneral and western cultures in particular as a result of the tranplahin movement and other important means.
The modern poet wood to ask some important characters to enrich his technician text inspite the fact that this is not a new way in Arab poetry but it takes avarant – criented to become outside the limits of rigid description within ongoing kinematic structure to be in
The relation ship between Syria and Lebanon is a distinguished one
because of the cultural social geographic and historical common factors. So
that, Syria considers that Lebanon has a stratieyical depth for it, especially its
conflict with (Israel) does end and parts of its lands still under the occupation
of the Zionist thus, any conflict in Lebanon between parties and ethnics
groups could be considered an important influence on the bases of the Syrian
policy. Moreover the issue of Palestine which is considered the central issue
for Syria and Arab as whole. In addition to some of the political movements
that happened in the region itself. It could be said that Syrian interference in
Lebanon has a positive infl