Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. Therefore, it is critical for researchers to understand molecular biology in greater depth. In several diseases including cancer, abnormal miRNA expression has been linked to apoptosis, proliferation, differentiation, and metastasis. Many miRNAs have been studied in relation to cancer, including miR-122, miR-223, and others. Hepatitis B and C viruses are the most important global risk factors for HCC. This study is intended to test whether serum miRNAs serve as a potential biomarker for both HCC and viral infections HBV and C. The expression of miRNA in 64 serum samples was analyzed by RT-qPCR. Compared to healthy volunteers, HCC patients' sera expressed significantly lower levels of miR-122 and miR-223. Furthermore, we compared the expression of these miRNAs between early-diagnosed HCC patients and healthy controls. There was a significant difference between miR-122 expression in HCC sera and healthy volunteers' sera (0.000 and 0.253, respectively), with a P value of <0.0001. Early diagnostic patients without treatment had completely deleted miR-122 expression levels, while those treated had slightly elevated levels. Clearly, miR-122 has been identified as a biomarker for early detection and follow-up of HCC treatment. HBV and HCV specimens expressed significantly lower levels of miRNA than normal samples with a P value of <0.0001. It is recommended that these findings be further investigated for diagnostic purposes. Further, these miRNAs are highly specific for diagnosing HCC, HBV, and HCV, making them valuable therapeutic indicators.
The research covered "the portrayal of women in the Baghdadi proverbs" in the introduction to the proverbs, their importance and the early ones who wrote them, and proverbs in the Arab societies, and was prepared to speak about the Baghdadi proverbs. Then he went on to mention a number of Baghdadi proverbs that talked about women and how to portray them, and the injustice that the society inflicted on them as a result of the look of contempt that is seen to them.
هذه الدراسة محاولة جادة لفهم تطور التعليم في كربلاء المقدسة خلال المدة 1958-1968، تناول البحث محاور عدة، ابتدأ في رياض الاطفال، ومن ثم التعليم الابتدائي في كربلاء، فالتعليم الثانوي. اعتمد التربية، التخطيط، الارشاد، فضلاً عن عديد الكتب التي اعتمدت الوثائق والتي سيجدها القارئ في ثبت المصادر.
لقد عرفت بلادنا ظاهرة ( اطفال الشوارع ) والتي تشمل عمالة الاطفال والمتشردين والمتسولين ، فتحولت من مشكلة على نطاق نسبي الى ظاهرة واسعة جداً تتضمن المخاطر المصاحبة لها ، إذ إنها ظاهرة منتشرة جداً في جميع المدن العراقية تصف في كثرة انتشارها في المناطق المليئة بالسكان .
إن ظاهرة عمالة الاطفال والتي ينصب عليها إهتمامنا في هذا البحث تشير الى نشاطات تقع خارج نطاق قوانين العمل وشروطه الاجتماعية ،
... Show Moreلعلنان نق اأ اّاد أَ ثرالشم تَ ام يلثهاتس يل هامني ا يل ب نال س ييننانن ب د اّاد ين ا يلنال ني نا ي
تنن عل ينني مَ ينط يئني، يلقد قنقج ع طمنق ي ق ن ب ييننن ثع يلأحليث على اّأ يلحنلاي يل و هاع مأني يلقاد
نضعُ ن ش ن نّهن عنلثن نُرأ مُ يلأحلي ش ث دّ ذ ن طمنقيٍ نل ني.
حلُ يلعل م ييننننني يلقد قهقبم ل ي مناي يل ب نال س يلش هامت ققالنم يلش نانئد يلأل ي يلقاد ى قُعناى ق ننام
يل ش نال س يل و نال د لاى يين ان د شّ حناب، اد نىمق
The study consisted of an introduction، two chapters and a conclusion
The first، tagged topic (: His lineage، birth، and family)، traces the lineage، birth، and family of Abd al-Ilah Hafez.
The second topic، which came under the title (The Role of Abd al-Ilah Hafez in the printing of currency)، was concerned.
The study relied on a large number of unpublished documents، foremost of which are the documents of the Central Bank of Iraq. It contained a lot of information about its administrative activity، its positions، orders and plans in this direction.
The House of Books and Documents is considered Al-Manhal، which is indispensable for any research to study the royal his
... Show MoreThe Arabs took care of the Arabic language, collected it, and set standards governing it; This is for fear of melody, in order to preserve the language of the Noble Qur’an from distortion, after many of those who are not fluent in Arabic entered Islam; There were many reasons for setting linguistic standards, but although scholars set these standards, we see them often deviate from them, as well as the language’s departure from these restrictions that they set, because language cannot be restricted, as it is subject to the law of use.
The expression is a prominent feature of the Arabic language, but it is one of the characteristics that are inseparable from it. The expressive aspects of each other.
The issue of Arab differences and their impact on the divergence of meaning is one of the issues that have preoccupied the minds of the Arabic language owners and their views went to various doctrines. Introduction: (Whenever I finished a question concluded with a verse related to any download, and followed by the need for expressing, interpretation and interpretation) I found him in some of the Aarabip more than the face of some of the vocabulary raised and erected and a jar, when the verses of the Koran, resulting in a research lies between Grammar and the Koran under
The writings of famous French novelist Antoine de Saint- Exupery being describes his life and his career as a pilot. That's where aviation and modern means of transport at the beginning of the twentieth century. It is also through his writings that tainted documentary chronicled the history of occupied France by the Germans in World War II. Has contributed to the publication of documents and real events and attended by military missions. However, before he died, wrote us a novel immortal "The Little Prince ", which is quite different from previous writings in terms of dependence entirely on the imagination. And are almost close to science fiction to fact that the hero falls to the ground in a vague, of a small asteroid. We are tryi
... Show MoreThe Arabic medicine books have emphasized that the Arabic Pediatricians in their scientific career ,who searched in Various aspects concerns with pediatric , as well as that some medical results and phenomena emphasized some data related to this subject . Which operates at the present time attention and concern towards human and in public and towards Pediatricians in special.
This research contained from an introduction that interpreted the Arabic medical heritage in progressing medicines in Europe then it mentioned the prominence Arabic pediatricians . the researcher depended on references and sources which will the reader had found through research.