Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. Therefore, it is critical for researchers to understand molecular biology in greater depth. In several diseases including cancer, abnormal miRNA expression has been linked to apoptosis, proliferation, differentiation, and metastasis. Many miRNAs have been studied in relation to cancer, including miR-122, miR-223, and others. Hepatitis B and C viruses are the most important global risk factors for HCC. This study is intended to test whether serum miRNAs serve as a potential biomarker for both HCC and viral infections HBV and C. The expression of miRNA in 64 serum samples was analyzed by RT-qPCR. Compared to healthy volunteers, HCC patients' sera expressed significantly lower levels of miR-122 and miR-223. Furthermore, we compared the expression of these miRNAs between early-diagnosed HCC patients and healthy controls. There was a significant difference between miR-122 expression in HCC sera and healthy volunteers' sera (0.000 and 0.253, respectively), with a P value of <0.0001. Early diagnostic patients without treatment had completely deleted miR-122 expression levels, while those treated had slightly elevated levels. Clearly, miR-122 has been identified as a biomarker for early detection and follow-up of HCC treatment. HBV and HCV specimens expressed significantly lower levels of miRNA than normal samples with a P value of <0.0001. It is recommended that these findings be further investigated for diagnostic purposes. Further, these miRNAs are highly specific for diagnosing HCC, HBV, and HCV, making them valuable therapeutic indicators.
Bohemia AL-Kharab for Salah Salah Which contain 477Paper deal With History of Nathion This Novel Has a different styl from another IraQis Novels, this Novel has no conversation this is the basic reason Which hav this research .
The novel have 3 versions , the first one deal with explain the text in different ways , the second contains the realation ship between the text and the reader .
Which appear very clear in novel from up to down , whil the third one and the last explaine
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The time bylose the relation in the novel.
The last thing is the conclusion which has the simple things conclude by the researcher from several readings to the novel
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... Show MoreResumen:
En este artículo se indaga sobre fenómenos como la metáfora, la metonimia, la polisemia, y la homonimia en las lenguas árabe y española, según la teoría cognitiva, basada en el pensamiento y la práctica lingüística. Esta teoría intenta investigar la relación entre el lenguaje humano, la mente y la experiencia. En realidad, los fenómenos que estudiaremos crean ambigüedad léxica y sintáctica tanto en árabe como en español. Además, dichos conceptos tienen sus propias características, especificaciones y formas en cada lengua.
Abstract:
This article studies phenomena such as metaphor, metonymy, polysemy, homonymy in Arabic and Spanish, according to cognitive theory, based on linguistic thought a
... Show MoreThe insects like other creatures in the wide world, and there are more than a million class and type of these objects, some of which human haunted since the old to the present day.
In this study highlight the insect bee addressing her life and behavior, and the novelty of her and wonders what mystified by the minds of men that her world is full of mysteries and surprises drew the attention of workers in the natural history of the study and scrutiny of methods and different characteristics of scientists as she gives more than it takes. It appeared that the Islamic heritage has singled out these insects with something of interest and precise detail, but that God Almighty made suras from the Koran carrying insect name two Sura
... Show MoreUsing religious characters which come from religion is a significant means that poets applied in their texts. The Iraqi poet Adib Kamal Aldin applied religious characters as an active means helping the theme of the text and playing a great role in expanding the meanings and their implications in the text.
يهدف البحث إلى تحليل خطوات التكلفة المس تهدفة الخضراء من أجل تخفيض تكاليف الفشل البيئية المتمثلة بالتكاليف الداخلية والخارجية للشركات الصناعية وجعل منتجاتها صديقة للبيئة وذات ضرر قليل من خلال تخضير المنتجات والتي تؤدي إلى تخفيض تكاليف الفشل البيئية
The Arab woman expressed the life of oppression that she suffers from in her masculine environment, as she expressed her linguistic abilities with eloquence and intelligence, as she did not neglect philosophy, wisdom, and exhortation
as important aspects emerged related to the management of the caliphate and how it was transferred, and the clarification of the political trends and transformations at the end of their lives. In addition, how the Rightly Guided
The research titles “Ammorrite tribes and their historical role in Mesopotamia and Levant” deals with tribe structure, nomination, political and cultural roles of these tribes in Mesopotamia and Levant, as it terminate Sumerian presence in Iraq and changed historical course and contributed in changing population landmarks and started new bright era, in addition to admitting new beliefs, gods and laws, beside ruling principles which became tribal, i.e., dynasties instead of Sumerian rulings based on religion belief.
Assyrian merchants established in the second millennium BC Assyrian commercial settlements in Anatolia, and these settlements had a great cultural value
تحليل الأخطاء الصوتية في بعض كتب اللغة الروسية الدراسية