Diabetes mellitus caused by insulin resistance is prompted by obesity. Neuropeptide Nesfatin-1 was identified in several organs, including the central nervous system and pancreatic islet cells. Nesfatin-1 peptide appears to be involved in hypothalamic circuits that energy homeostasis and control food intake. Adiponectin is a plasma collagen-like protein produced by adipocytes that have been linked to the development of insulin resistance (IR), diabetes mellitus type 2 (DMT2), and cardiovascular disease (CVD). Resistin was first identified as an adipose tissue–specific hormone that was linked to obesity and diabetes. The aim of this study was to estimate the relationship between human serum nesfatin-1, adiponectin, resistin concentration, and obesity with T2DM. The results show a significant increase in serum neisfatin-1 and resistin levels in the obese diabetic group compared to the non-obese diabetic group. Adiponectin levels had a highly significant decrease in the obese diabetic group compared to the non-obese group and obese control group. Serum Nesfatin-1 and some variables, there was a significant positive correlation with (BMI, insulin, HOMA-IR), and serum resistin had a significant positive correlation with (BMI, WC, TG, insulin, HOMA-IR).On the other hand, there was a negative correlation between serum adiponectin and (BMI, TG, and HOMA-IR). The present results suggest that nesftin-1 may have a role in controlling food intake as well as the development of IR in obese patients.
Density Functional Theory (DFT) method of the type (B3LYP) and a Gaussian basis set (6-311G) were applied for calculating the vibration frequencies and absorption intensities for normal coordinates (3N-6) at the equilibrium geometry of the Di and Tetra-rings layer (6, 0) zigzag single wall carbon nanotubes (SWCNTs) by using Gaussian-09 program. Both were found to have the same symmetry of D6d point group with C--C bond alternation in all tube rings (for axial bonds, which are the vertical C--Ca bonds in rings layer and for circumferential bonds C—Cc in the outer and mid rings bonds). Assignments of the modes of vibration IR active and inactive vibration frequ
... Show MoreSeeds, beans, leaves, fruit peel and seeds of five plants (Ferula assa-foetida, Coffea robusta, Olea europaea, Punica granatum and Vitis vinifera, respectively) were extracted with four solvents (distilled water, 80% methanol, 80% acetone and a mixed solvent that included methanol, ethanol, acetone and n-butanol at proportions 7:1:1:1). Such manipulation yielded 20 extracts, which were phytochemically analyzed for total polyphenols (TP) and flavonoids (TF). The DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity (RSA) and DPP-4 (dipeptidyl peptidase-4) relative inhibition activity (RIA) were also assessed for each extract. The results revealed that mixed solvent extract of V.
... Show MoreIn this work, the preparation of new multidentate Schiff-base lig and and its metal complexes are described. The formation of the lig and{ 2,2`((5-methyl-1,3-phenylene)-bis-(oxy))-bis-N`(E`)-2- hydroxybenzylideneacetohydrazide}[H2L] was prepared from the reaction {2,2-((5-methyl-1,3-phenylene)-bis-(oxy))- di-(acetohydrazide)}[M]precursor and salicylaldehyde in a 1:2 mole ratio, respectively. The reaction of the lig and [H2L] with (Cr+3 , Mn+2 and Fe+2 )metal ions in a 1:2 (L:M) mole ratio. Ligand and complexes were characterised via spectroscopic analyses; [FT-IR, UV-Vis spectroscopy,(C.H.N) microanalysis, chloride content, thermal analysis(TG), electrospray mass, magnetic susceptibility and conductivity measurements. The characterisation d
... Show MoreA new series of chalcone derivatives featuring an oxadiazole-quinoline moiety were successfully synthesized through a multi-step reaction sequence, commencing with quinoline-2-carboxylic acid as the starting material. First, the carboxylic group was chlorinated to form an acid chloride, following reacted with hydrazine hydrate. The resulting product underwent cyclization with carbon disulfide in an alkaline solution to produce 5-(quinolin-2-yl)-1,3,4-oxadiazole-2-thiol, followed by alkylation using chloroacetone. In the final step, an aldol condensation reaction was carried out by grinding the acetone derivative with various aromatic aldehydes, yielding the desired chalcones. The synthesized compounds were characterized by Rf, FTIR,
... Show Moreلظهور كثير من الاراء التفسيرية والنقدية والتي تباينت في كثير من الاحيان وبخاصة من المفسرين والمستشرقين لاختلاف المشارب الفكرية لكلا الفريقين وهو ما تطلب تاصيلا لعملية النقد والمقارنة بين المنهجين
لقد اعتبر انسان وادي الرافدين قديماً، الكون عبارة عن دولة كونية، وكل مافيه - اي الكون كان يعد عبارة عن ذوات فردية، فكل حي وجماد وفكرة مجردة وكل حجر وكل شجرة وكل خاطر يتمتع بارادة ذاتية وشخصية خاصة، لقد تمثل الكون في ذهن الانسان بهيئة واحدة الا وهي نظام من الارادات فالكون ككل منسق انما هو مجتمع، أو دولة فكانت هذه الدولة الكونية تضم إلى جانب الشخصيات الفعالة في هيئة الحكم اعضاء لم يكن لهم نفوذ في السياسة ولا دور ل
... Show MoreThis research deals with Amicus Curiae as one of the judicial procedures widely spread in many common law countries on the one hand, and civil law countries on the other hand, as well as regional and international courts. We will seek to clarify what this procedure is, by defining it and distinguishing it from what may be suspected of judicial procedures, and then we will indicate the scope of resorting to it at the national, regional and international levels. We have supported the research with many judicial applications that used this procedure to demonstrate its importance.
يبحث هذا البحث في افعال المقاربة التي تعد من الافعال الناسخة في اللغة العربية التي تدخل على الجملة الاسمية فتبقي المبتدأ مرتفعا بها ويسمى اسمها وتنصب خبره وتقسم هذه الافعال الى اقسام ثلاثة افعال المقاربة وهي (كاد ,اوشك ,كرب هلهل ,قارب ) وافعال الرجاء وهي (عسى , اخلولق , حرى ) وافعال الشروع وهي (اخذ ,وهب ,بدأ ,انشا , شرع , اقبل ,قام ) وتشابه كاد في معناها وفائدتها جعل وشرع وعلى الرغم من عدم ذكر القران الكريم لأي اية فيها
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