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Small Nuclear RNA 64 (snoRNA64): A novel Tumor Biomarker for Pancreatic Cancer
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The pancreatic ductal adenocarcinoma (PDAC), which represents over 90% of pancreatic cancer cases,
has the highest proliferative and metastatic rate in comparison to other pancreatic cancer compartments. This
study is designed to determine whether small nucleolar RNA, H/ACA box 64 (snoRNA64) is associated with
pancreatic cancer initiation and progression. Gene expression data from the Gene Expression Omnibus (GEO)
repository have shown that snoRNA64 expression is reduced in primary and metastatic pancreatic cancer as
compared to normal tissues based on statistical analysis of the in Silico analysis. Using qPCR techniques,
pancreatic cancer cell lines include PK-1, PK-8, PK-4, and Mia PaCa-2 with different levels of snoRNA64,
including PK-1, PK-8, PK-4, and Mia PaCa-2. The level of expression is correlated with the cell line epithelial
or mesenchymal characteristics. Cell lines displaying epithelial characteristics such as PK-1, PK-8 show high
levels of snoRNA64 meanwhile, cell lines displaying mesenchymal characteristics such as PK-4, Mia PaCa-2
show low levels of snoRNA64. The level of expression is correlated with the cell line epithelial or
mesenchymal characteristics. After knocking down the PK-8 with high snoRNA64 expression, the epithelial
markers E. cadherin (E-cad) and Cytokeratin-8 (CK-8) are decreased, while mesenchymal markers Vimentin
(Vim), Cytokeratin-19 (CK-19), Metalloprotease -2 (MMP-2), and Metalloprotease-3 (MMP-3) are activated.
Those changes suggest that PK-8 responding to the snoRNA64 knock down protocol and increase in
mesenchymal function. Together, snoRNA64 expression may participate in epithelial to mesenchymal
transition (EMT) and mesenchymal to epithelial transition (MET), in which during metastasis these processes
are crucial. In addition, snoRNA64 may be considered as a potential diagnostic biomarker for both early and
invasive stages of PDAC. And due to its gradual expression decreases, it may be considered a barrier in tumor
progression.

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Publication Date
Wed Nov 06 2019
Journal Name
College Of Physical Education And Sports Science
(M.H) electronic system for goalkeepers
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Publication Date
Wed Nov 01 2023
Journal Name
College Of Physical Education And Sports Science
Electronic shorts for the disabled
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Publication Date
Sun Feb 03 2019
Journal Name
Journal Of The College Of Education For Women
Friendship for Students Intermediately School
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The present study intends to trace The friendship in puple and the differences in this according to the variables of age and sex .
The study sample includes (200) puple in intermediate, and secondary schools in Baghdad in AL- Karkh .The sample is the age of whom is ranging from (13) to (15) years .
Maghly scale for measuring the development of friendship is adopted in this study after adjusting it to the Iraqi environment . The Scale consists of (40) items .
The face and construct validity of the Scale is checked as well as its reliability which is checked by test- retest
The study reveals the following :
1 – There is positive effect of the interaction between the of middle scale friendship .
2 – There is No differe

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Publication Date
Thu Jun 01 2023
Journal Name
Southeast Asian Bulletin Of Mathematics
Presentation for G \wr Sing2
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Publication Date
Wed Jul 16 2014
Journal Name
Transactions Of The Asabe
Sorption Isotherms for Triticale Seed
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Triticale is being evaluated as a substitute for corn in animal feed and as a forage crop for Florida. Storage of triticale seed is difficult in Florida's hot and humid climate, and more information about the relationships between equilibrium moisture content (EMC) and equilibrium relative humidity (ERH) at constant temperature (sorption isotherms) of triticale is needed to develop improved storage methods. Therefore, the primary research objective was to measure the EMC for triticale seed at different ERH values at three different constant temperatures (5°C, 23°C, and 35°C) using six desiccation jars containing different saturated salt concentrations. The secondary objective was to determine the best fit equation describing these relati

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Publication Date
Mon Mar 07 2022
Journal Name
Journal Of Educational And Psychological Researches
Cognitive Behavior Therapy for Depression
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The current research aimed to identify the cognitive-behavioral therapy on people with depression, through the following hypothesis (there are no statistically significant differences in the sample before and after cognitive-behavioral therapy). The importance of research is highlighted through the use of cognitive-behavioral therapy, to be used in treating depression, anxiety and fears by health institutions. It is also considered as a reference for psychological studies related to this topic to be added to our libraries that already suffer from a scarcity of this type of resources. The cognitive-behavioral therapy was used in the treatment of five male subjects.

The study revealed the existence of statistically significant diff

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Publication Date
Wed Jan 01 2020
Journal Name
Journal Of Southwest Jiaotong University
Image Segmentation for Skin Detection
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Human skin detection, which usually performed before image processing, is the method of discovering skin-colored pixels and regions that may be of human faces or limbs in videos or photos. Many computer vision approaches have been developed for skin detection. A skin detector usually transforms a given pixel into a suitable color space and then uses a skin classifier to mark the pixel as a skin or a non-skin pixel. A skin classifier explains the decision boundary of the class of a skin color in the color space based on skin-colored pixels. The purpose of this research is to build a skin detection system that will distinguish between skin and non-skin pixels in colored still pictures. This performed by introducing a metric that measu

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Publication Date
Tue Sep 27 2022
Journal Name
Al–bahith Al–a'alami
Guidelines for covering online surveys
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Media and communication's research are varied in accordance to research approaches' variety which seeks to reach convergent social, psychological, political, economic, and technical point of views. Its main aim is to assimilate all the new variables in the communicative method, especially, social media sites research; concerning their methodology, tools and theories. It is due to their diverse - developed applications and their increased rates of public use becoming irreplaceable in our daily life. It is well reflected by their consequent impact on the the public beside their role in changing its views.

This clarifies the notable increase of scientific research that concern them manifesting the dialectical relations and interfere

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Publication Date
Sat Jan 01 2011
Journal Name
Iraqi Journal Of Physics
Dielectric Waveguide for Composite Materials
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The Maxwell equations have been formulated for a composite slab waveguide at x-band wave propagation. The eigenvalues of the system equations are obtained by using MATLAB program. These eigenvalues are used to obtain the wave propagation constant and a number of modes inside the slabs. A good correspondence was seen between the number of modes and the cut off thickness. The parameter that affects the performance of waveguide is the slab thickness. The propagation constant is usually adopted to characterize this type of waveguide and show how the cutoff frequency of the mode in the slab is increased dramatically by decreasing the frequency.
Our study focused on lower modes, the results for the transmission coefficient are then used to

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Publication Date
Sun Jun 30 2013
Journal Name
College Of Islamic Sciences
Controls for innovation in interpretation
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Renewal is generally considered an urgent requirement of life, and a section of its continuation, because renewal means that life exists and continues, and just as renewal is in life, renewal is in science, and in this research the issue of renewal in the science of interpretation, and showed through research that renewal in This science was an urgent demand throughout the Islamic ages, as the research showed the necessity of renewal in the material of interpretation, its method and methods, and the researcher presented the opinions of schools about renewal in the interpretation of the Noble Qur’an inferred by living models that refer to their owners.

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