Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
بدأت الشركات تخطو خطوات متسارعة باستخدام أنظمة تكنولوجيا المعلومات في عملياتها المالية وباعتماد قليل على الورق والذي يتم الاحتفاظ بالنسخ الأصلية منه تعزيزا للإجراءات التي تمت معالجتها الكترونيا. إن ممارسة الشركات وبشكل متزايد الأسلوب الواقعي (Virtualization) في علاقاتها مع الموردين والمستهلكين والشركاء أدى للحاجة المتزايدة للثقة والتأكيد على مثل هذه العلاقات مما يولد ضغطا كبيرا ع
... Show Moreحل الاشكالية المنهجية في العلوم الانسانية المنهج البنيوي انموذجاً مقترحاً
الحمد لله رب العالمين، والصلاة والسلام على سيد المرسلين، محمد وعلى آله وصحبه أجمعين وبعد:
فإن الله تعالى خلقنا أزواجا، وجعل منا الذكر والأنثى يميل بعضهم إلى بعض بالفطرة والطبع ليكونا بمشيئة الله أسرة، ويرزقان بنين وحفدة، وهذه سنة الله تعالى في الخلق لا يزيغ عنها إلا هالك.
ومن نعم الله تعالى على بني البشر أن جعل النكاح المشروع لا السفاح الممنوع أساس العلاقة بين ال
... Show Moreيعتبر مفهوم المجتمع المدني من بين سلة المفاهيم التي حملت لوائها واعادت رفعها حركات الموجة الثالثة من الديمقراطية في العالم التي نادت بالتعددية والانتخابات الحرة ...الخ .
Praise be to Allah and peace be upon our master and lover of our hearts and our souls doctor Muhammad and divine , especially the rest of God in Aladdin , and a curse on all the enemies to the day of judgment ,
After : The issue of education of man , and brought up within the curriculum properly and comprehensively cannot be completed for the seriousness and accuracy without revelation , the Qur'an inspiring , than when gentle expert , is a factory of man and humanity , in fact ... is the process of modifying behavior, one of the goals of education community at various levels in the family the school and the whole university and other educational institutions and community-based factories humanity that th
... Show Moreيرمي البحث الحالي الى تقويم أداء طالبات الصف الاول متوسط في مهارات القراءة الجهرية ، وذلك من خلال الاجابة عن هدفي البحث : 1- ما مستوى أداء طالبات الصف الأول المتوسط في كل مهارة من مهارات القراءة الجهرية ؟ 2- ما مستوى الأداء العام لطالبات الصف الأول المتوسط في القراءة الجهرية ؟ يقتصر البحث الحالي على: 1- مهارات القراءة الجهرية 2- عينة من مدارس البنات الن
Abstract traditional acculturation is one of the significant phenomena which is used in the old and modern arabic poetry. Poets have found in this tradition and flourishing arena for acculturation and interaction to Express their thoughts and inspection
The Current research aims to identify ( The effects of Daniel Model in Cognitive Motivation for the Students of the Third grade average ) , To verify the objective of this research , the researchers added nul hypothesis following : There is no difference is statistically significant at the level of ( 0.05 ) between the average scores of students who studied Daniel Model and the average students who studied by using traditional method in Cognitive Motivation scale. The research was conducted on a sample of the average Third grade students in a medium Al – sadiq Al – Ameen secretary for boys affiliated to the General Directorate for Educational in Baghdad Al – rusafa 2 and for academic year ( 2014 – 2015 ) , the researchers adopted
... Show Moreتناول البحث اثر النساء في البيت العباسي وتأثيرهن الثقافي والعلمي في التراث البغدادي ، وانعكاسه على الواقع الاجتماعي الذي يعد بحد ذاته مظهر من مظاهر الانسجام والتلاحم بين الماضي والحاضر إذ تركن أثرا بارزا في الحضارة والعلم وأسهمن بصورة مباشره او غير مباشره في دعم وتطور الحضارة العربية الإسلامية .
The research aims to identify the level of selective visual attention among students of the faculties of education at the University of Mosul. To achieve the goal of the research, the researchers chose a stratified random sample of students from the faculties of education at the University of Mosul for the academic year (2020-2021). The sample size was (652) students from the scientific and humanitarian specializations, the second and fourth stages. The researchers developed a test of multiple-choice to measure the selective visual attention, which consisted of (42) items. The results revealed that the students of the faculties of education for human sciences have an appropriate level of selective visual attention. There are statisticall
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