Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
The study seeks to identify e-governance requirements in human resources management, which are (administrative requirements, technical, human, financial, and security) which is a new style differs from the traditional management pattern, where work depends on multiple forms and methods of Tools, (e. g. computers and various electronic software), by relying on powerful information systems that help to make management decisions as quickly and less effortless and less expensive to keep up with the tremendous technological advancements in the field of information and communication technology revolution.
The sample included 132 Person who constitute a position (Director General, assistant Director General, section managers and d
... Show MoreSeen in Iraq that the volume of insurance activity in the case of a clear deterioration and a sharp decline in demand for life insurance, because of reluctance by senior members of the Iraqi society on the demand for life insurance. The study was descriptive approach in identifying and addressing variables, namely the (perception of risk need of the individual trends in personal income of the individual insurance awareness of the individual customs and traditions of communal religious belief of the individual age and sex of the individual methods promotional company competitive alternatives to the insurance service life inflation rate service life insurance) indepen
... Show Moreيهدف هذا البحث إلى معرفة أثر استخدام دورة التعلم في اكتساب المفاهيم الصرفية واستخلاصها لدى طالبات قسم اللغة العربية بكلية التربية للبنات وقد صيغت فرضيتان مفادهما أن ؛ 1- لا توجد فروق ذات دلالة إحصائية بين متوسط درجات طالبات المجموعة التجريبية اللاتي يدرسن المادة الصرفية في دورة التعلم ومتوسط درجات طالبات المجموعة الضابطة اللاتي يدرسن المادة الصرفية بالطريقة القياسية لاكتساب المفاهيم. 2- لا توجد فروق ذ
... Show MoreAbstract:
This study seeks to shed light on the important processes are linked to the impact of accounting information on the behavior of producer and user of information and are urging informational and informational use. That accounting as a system of accounting information and functions of the delivery of information to decision makers Under behavioral entrance to the formulation of accounting theory should be taken into account Othertlk accounting information in the behavior of the decision maker which requires an explanation of human behavior and predictable.
On the other hand that the accounting information that should be delivered to the decision maker will affect your beha
... Show MoreAbstract
Dame Ngaio Edith Marsh (1899-1982), a writer of detective fiction, was born
at Christchurch, New Zealand. Her hero, Chief Detective Inspector Roderick Alleyn,
appears in her first novel, A Man Lay Dead (1934), and in subsequent novels
including Death and the Dancing Footman (1942). She wrote twenty detective novels.
The Dancing Footman, Thomas, listening to a playful song from the smokingroom's
radio where William lay dead after being killed by his brother, Nicholas,
provides the most suspected guest at Highfold with badly needed alibi. The murderer,
Nicholas, plans an almost perfect crime, but the dance of this footman spoils his
scheme. When Alleyn and his group of policemen stage a show in which the
يهدف البحث الى قياس مدى التطبيق والتبني للقيادة الملهمة في المنظمات العامة، وقد اشتقت مشكلة البحث النظرية من وجود فجوة معرفية وذلك لقلة الدراسات والبحوث التي تناولت متغير البحث بأبعاده (الرؤية المستقبلية، الثقة بالنفس، تمكين العاملين، ادارة التغيير)، واعتمد البحث المنهج التحليلي عن طريق استعمال الاستبانة في المنظمة التي تم اختيارها وذلك لكونها تعد من المنظمات الاساسية في تقديم الخدمات التعليمية المهمة في
... Show MoreThe audit committees are considered to be one of the most important committees because of the role they play in supervising and monitoring the process of formation of the financial statements and correction of the internal supervising system also strengthening the independency of the internal and external audit. Matters which increases the efficiency and integrity of the financial statements which reflects positively on competence of board of directors and then enhance the position of the company through increasing the trust of the users of the financial statement within the company.
Therefore, this research deals with the evaluation of the performance of the audit committees in Iraqi banks according to the local rules and
... Show MoreFind extract This research aims to find out (after learning strategy cells in the development of critical thinking and reflective thinking at the fifth-grade students in the geographic literary material). And follow researcher Almhnj demo for the purpose of achieving the goals of current research and design on an experimental group and a control with a test group after me and adopted chose researcher sample Find a way Mqsidih students of junior high Kadhimiya Boys of the breeding Baghdad / Karkh II and to verify the effectiveness of the search coined researcher hypotheses following cases: - 1. No statistically significant between the mean scores of the experimental group and the students taught her students that strategy differences (lea
... Show MoreThe current research aims to study (the effect of strategy of analysis - synthesis duality in the collection of scientific fourth stage students and high-order thinking in Biology material). For evidence the objective of the research, the researcher formulated the following two null hypotheses: 1. There is no significant difference at the statistical level (0.05) between the average of scores of the experimental group students that will study according to the dualism strategy of analysis and structure and the average of scores of the controlled group students that will study according to the normal way in the collection. 2. There is no significant difference at the statistical level (0.05) between the average of scores of the experimenta
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