Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
Black slaves formed a section of the Murabit community, and they had an important role in wars and in settling battles to the Murabit state. Murabit state lords have depended on them in many scales such as, wars or within the community boarders
تعد الطوابع احدى وسائل الاتصال المهمة في المجتمع لما تتميز به من مستوى في القيمة الفنية والفكرية، فضلاً عن كونها وسيلة من وسائل الخطاب الاعلامي وذلك لتعدد وظائفها التي من ابرزها:التوثيق لمرحلة معينة وحدث ما.التداولية الرسمية للمراسلات المحلية والعالمية.الاعلانية كونها تعطي انطباعاً عن مراحل التطور والتقدم الاجتماعي والحضاري والسياسي للمجتمع.الدعائية لما تتضمنه من مفاهيم وأفكار وتوجهات سياسية واقتصادية
... Show MoreThe aim of this research is to find out about the methods used by the teachers of the subjects (choir, voice training, singing groups) used to warm up in voice training. In the Department of Music of the Faculty of Fine Arts University of Baghdad. The limits of this research were for the academic year (2017-2018). Explanation in the theoretical framework of warm-up types The first part of the body warms the body in terms of relaxation, body moderation, head rotation, tongue exercises, mouth opening, facial mask movements, yawning.The second course will warm up the sound exercises warm up the sound through different ladders (diatonic and chromate), and ladder accordions.And the third topic warm up the impris
... Show Moreعرف الإنسان اللؤلؤ منذ عصورما قبل التاريخ ، حيث كان يجمعه من الأصداف التي كانت تلقي بها الأمواج على الساحل . و لم تُمارس مهنة الغوص إلا في مرحلة لاحقة لم يحدد تاريخها .
الادراك السياسي للاصلاح الاداري في العراق
The strategy of designing the covers of international magazines emerges as one of the expressive means that reflect the emotional and expressive aspects and employ them according to the spatial transformations and the struggles of globalization to usurp the intellectual, cultural, value and civilizational essence of man, which makes him vulnerable to psychological and spiritual alienation and becomes the abstract meaning of identity and culture, and the empowerment of cultural invasion and the control of consumer thought The contemporary globalist on the largest area and the globalization of the peoples of the world, and the study came in the first chapter: the general framework that includes the problem of the research to raise in our m
... Show MoreThe current research dealt with the rapid development of industrial product design in recent times, and this development in the field of design led to the emergence of modern trends in many terms and theories to direct greater interest in the cognitive foundations of design and its relationship with the components of other natural sciences, and despite the impressive technological development, nature remains With its content of formative values and structural dimensions, it is the first source of inspiration and the source of all modern mathematical sciences and theories, as God made them tend towards organization to continue to provide us with endless inspiration. Hence, the fractional one, which is an important part of dedicating the d
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