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bsj-6431
Predictive Significance of Interleukins 17A and 33 in Risk of Relapsing–Remitting Multiple Sclerosis
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Cytokines are signaling molecules between inflammatory cells that play a significant role in the pathogenesis of a disease. Among these cytokines are interleukins (ILs) 17A and 33, and accordingly, the current case-control study sought to investigate the role of each of the two cytokines in the risk of developing multiple sclerosis (MS). Sixty-eight relapsing-remitting MS (RRMS) Iraqi patients and twenty healthy individuals (control group) were enrolled. Enzyme linked immunosorbent assay (ELISA) kits were used to determine serum levels of IL-17A and IL-33. Results revealed that IL-17A and IL-33 levels were significantly higher in MS patients than in controls (14.1 ± 4.5 vs. 7.5 ± 3.8 pg/mL; p < 0.001 and 65.3 ± 16.3 vs. 49.3 ± 20.0 pg/mL; p < 0.001, respectively). Receiver operating characteristic (ROC) curve analysis demonstrated that IL-17A was a very good predictor of MS (area under curve [AUC] = 0.869; 95% CI = 0.779 - 0.960; p < 0.001; cut-off value = 10.2 pg/mL; sensitivity = 80.8%; specificity = 75.0%). A similar prediction was presented by IL-33, but the AUC value was lower (AUC = 0.762; 95% CI = 0.63 - 0.89; p < 0.001; cut-off value = 56.4 pg/mL; sensitivity = 70.6%; specificity = 70.0%). Multinomial logistic regression analysis confirmed the significance of IL-17A and IL-33 in MS risk, and under three models of analysis, the estimated odds ratios for IL-17A (1.50, 1.49 and 1.50, respectively) and IL-33 (1.05, 1.05 and 1.06) were above 1.0. Patients stratified by gender (male and female), expanded disability status scale (EDSS: < 3 and ≥ 3) or medication (pre- and post-medication) showed no significant differences in serum levels of IL-17A and IL-33 for each stratum. However, with regard to response to medication, it was found that responding patients showed significantly higher levels of IL-33 than non-responders (70.9 ± 12.2 vs. 57.2 ± 18.2 pg/mL; p = 0.018). This difference was not observed when considering IL-17A. Pearson correlation analysis between IL-17A and IL-33 revealed that both cytokines were not significantly correlated. In conclusion, the study indicated that IL-17A and IL-33 were up-regulated in serum of MS patients, and this up-regulation was not influenced by age, gender, EDSS or medication status, but the elevated level of IL-33 was more pronounced in patients who responded to medication.

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Publication Date
Sat Sep 04 2021
Journal Name
القانون والعلوم السياسية
المصالح الامريكية في القارة الافريقية بعد عام 2000
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تنشر الولايات المتحدة قوات في جميع دول القارة الافريقية بهدف السيطرة الكاملة عليها وتحقيق اهدافها ومصالحها

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Publication Date
Sun Dec 02 2018
Journal Name
Arab Science Heritage Journal
عمارة عمارة القلاع وتخطيطها في العراق (دراسة مقارنة)
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This paper shed light on castles in Iraq through Othman reign to know their sorts , and studying planning concentrating on the nature of architecture , this is a serious trying to study and important  side of military architecture in Iraq with its reasons of building them which had related with political, military , social ,and economical circumstances of country . 

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Publication Date
Tue Jan 01 2008
Journal Name
Journal Of Educational And Psychological Researches
مواجهة مشكلة المخدرات في العراق بين الواقع والمستقبل
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لم تكن المخدرات وليدة هذا العصر فقد عرفها الانسان منذ القدم وحاربتها المجتمعات القديمة ثقافياً واجتماعياً ودينياً ، حيث تعتبر المخدرات اخطر كارثة عرفتها البشرية في تاريخها وبدأت تتطور لتصبح تجارة عالمية غير مشروعة ترعاها عصابات منظمةهدفها تدمير طاقات وقدرات وقيم الشباب آمال هذه الامة وكنزها الحقيقي وهذا يعني تفريغ المجتمع من العقول المبدعة فيه حتى يبقى مجتمعنا متخلفاً من السهل السيطرة عليه.

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Publication Date
Tue Oct 05 2021
Journal Name
Arab Science Heritage Journal
وقفة مع التأويل اللغوي في تفسير القرآن الكريم
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The significance of interpretation for linguists varied , and its methods varied between appreciations, deletion, understanding the meaning

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Publication Date
Tue Dec 11 2018
Journal Name
Arab Science Heritage Journal
غربة غربة الشعراء المشردين وحنينهم في العصر الجاهلي
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Alienation, and Westernization and away, whether forcibly sense exile or voluntary in the sense of migration, it will generate nostalgia, and a sense of overwhelming homesickness spatial or alienation spiritual (emotional) and perhaps alienation resulting from exile or forced deportation by the authority

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Publication Date
Sun Mar 26 2023
Journal Name
Arab Science Heritage Journal
التعبير الاصطلاحي في آثار ابن المقفع- دراسة دلالية
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Each of the languages ​​possesses a set of phenomena that researchers in its sciences should stop at to explain the secrets of this language, including the phenomenon of idiomatic expression. Perhaps this phenomenon may constitute an obstacle to non-native speakers of the language or even the native speakers themselves. The Arabic language is full of these expressions, Which needs us to dedicate its own studies to it so that we can collect it in a dictionary that includes and collects it with explanation and interpretation of its semantics

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Publication Date
Fri Jun 30 2023
Journal Name
Journal Of The College Of Islamic Sciences
الصورة الفنية للأزهار في شعر ابي وكيع التنيسي
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ارتبط الانسان بالطبيعة بأشكالها المختلفة ارتباطا وثيقا ، فهي تمثل الحاضنة له بمجالات حياته كلها، فما كان من الأدباء الا أن يجعلوها في كثير من الأحيان مادة لأدبهم وأرضية خصبة لنتاجهم، فتمظهرت بصورها المختلفة وحاجة الانسان لها وخيرها وشرها في الأدب على مدى التاريخ، والعرب شأنهم شأن غيرهم من الأمم فمنذ عصر ما قبل الاسلام كانت الطبيعة منفذا مهما وملجأ للشعراء في انتاج الأدب وابداعه وإلى يومنا هذا، ونحن إذ نتحد

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Publication Date
Sat Mar 01 2014
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
دور محاسبة التكاليف في إبلاغ الإدارة بتكاليف الجودة
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Due to the great technical developments in the field of informational knowledge, technological and productive changes and intense competition among institutes in the era of globalization, focus of these institutes on the notion of total quality management has been increased. Quality costs have represented an essential ratio of the production costs, a matter that requires preparing information about these costs, Because of that, the need for preparation and availability of accounting information system to measure and prove these costs has been emerged.

        The descriptive analytic method has been used here to answer the questions raised in this study. Among the results that have been reached

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Publication Date
Mon Mar 20 2023
Journal Name
مجلة الترجمة واللسانيات
التضاد في اللغة السريانية / دراسة لغوية سامية مقارنة
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يسلط هذا البحث الضوء على ظاهرة لغوية، والتي يطلق عليها تسمية "التضاد". يبين هذا البحث مفهوم هذه الظاهرة، خصائصها، أنواعها، وأسبابها، في اللغتين الساميتين: السريانية والعبرية. حيث تم اعتماد المنهج المقارن في دراسة هذه الظاهرة اللغوية وتبيان وجوه التشابه واالختالف في ماهية هذا النوع من المفردات، أي األضداد، في اللغتين: السريانية والعبرية. ويشير البحث إلى نوعين من التضاد وهما: التضاد الذي يكون بين مفردتين مستقل

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Publication Date
Fri Feb 08 2019
Journal Name
Journal Of The College Of Education For Women
المعوقات والالتزامات الأسریة التي تواجھ المراة في عملھا
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This research aims to understand the main problems and family
commitments faced by working women, and make proposals that would stop or
lessen them, the researcher made questionnaire , applied on a sample of (20)
university female teachers, the study showed that the main problems in respect to
their importance as: Anxiety of leaving children at home alone, the weak role of the
nurseries and kindergartens in taking care of the children, relative large number of
children per family which would lead to more commitments, and the unavailability
of convenient working arrangement for working mothers.

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