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bsj-6431
Predictive Significance of Interleukins 17A and 33 in Risk of Relapsing–Remitting Multiple Sclerosis
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Cytokines are signaling molecules between inflammatory cells that play a significant role in the pathogenesis of a disease. Among these cytokines are interleukins (ILs) 17A and 33, and accordingly, the current case-control study sought to investigate the role of each of the two cytokines in the risk of developing multiple sclerosis (MS). Sixty-eight relapsing-remitting MS (RRMS) Iraqi patients and twenty healthy individuals (control group) were enrolled. Enzyme linked immunosorbent assay (ELISA) kits were used to determine serum levels of IL-17A and IL-33. Results revealed that IL-17A and IL-33 levels were significantly higher in MS patients than in controls (14.1 ± 4.5 vs. 7.5 ± 3.8 pg/mL; p < 0.001 and 65.3 ± 16.3 vs. 49.3 ± 20.0 pg/mL; p < 0.001, respectively). Receiver operating characteristic (ROC) curve analysis demonstrated that IL-17A was a very good predictor of MS (area under curve [AUC] = 0.869; 95% CI = 0.779 - 0.960; p < 0.001; cut-off value = 10.2 pg/mL; sensitivity = 80.8%; specificity = 75.0%). A similar prediction was presented by IL-33, but the AUC value was lower (AUC = 0.762; 95% CI = 0.63 - 0.89; p < 0.001; cut-off value = 56.4 pg/mL; sensitivity = 70.6%; specificity = 70.0%). Multinomial logistic regression analysis confirmed the significance of IL-17A and IL-33 in MS risk, and under three models of analysis, the estimated odds ratios for IL-17A (1.50, 1.49 and 1.50, respectively) and IL-33 (1.05, 1.05 and 1.06) were above 1.0. Patients stratified by gender (male and female), expanded disability status scale (EDSS: < 3 and ≥ 3) or medication (pre- and post-medication) showed no significant differences in serum levels of IL-17A and IL-33 for each stratum. However, with regard to response to medication, it was found that responding patients showed significantly higher levels of IL-33 than non-responders (70.9 ± 12.2 vs. 57.2 ± 18.2 pg/mL; p = 0.018). This difference was not observed when considering IL-17A. Pearson correlation analysis between IL-17A and IL-33 revealed that both cytokines were not significantly correlated. In conclusion, the study indicated that IL-17A and IL-33 were up-regulated in serum of MS patients, and this up-regulation was not influenced by age, gender, EDSS or medication status, but the elevated level of IL-33 was more pronounced in patients who responded to medication.

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Publication Date
Sun Jul 02 2006
Journal Name
Political Sciences Journal
اثر بديع الزمان سعيد النورسي على الفكر الاسلامي المعاصر في تركيا
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اثر بديع الزمان سعيد النورسي على الفكر الاسلامي المعاصر في تركيا

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Publication Date
Sat Sep 01 2007
Journal Name
Journal Of Economics And Administrative Sciences
أثر تحليل كلف النوعية على أساس الانشطة في تحقيق الميزة التنافسية
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يتطلب تحقيق تمايز الوحدة الاقتصادية في ظل استعمال تقنيات الأعمال الحديثة وازدياد المنافسة وعالمية الأعمال ضرورة الاهتمام بمستوى نوعية المنتجات وما تتطلبه هذه النوعية من كلف والتي تسمى بكلف النوعية، إذ ان العديد من الشركات العالمية قد قامت بدراسة وتحليل هذه الكلف ووضع برامج خاصة بها بهدف تخفيضها إلى أدنى حدٍ ممكن وبما يكفل تحقيق العديد من المنافع والتوفيرات في هذه الكلف وبما يرشد عملية اتخاذ القرارات

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Publication Date
Tue Nov 06 2018
Journal Name
Arab Science Heritage Journal
استخدام استخدام نظم المعلومات الجغرافية في الدراسات الاثارية ( تنقيبات جامعة الموصل).
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GIS is characterized by great potentialeties to deal with huge geographical data and conclude what is necessary for it. It was very useful to get use of the potentialities of this system of GIS in the field of archaeology and to harvest very accurate results in a relatively short time, compared to the old archaeological methods.

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Publication Date
Mon Nov 19 2018
Journal Name
Arab Science Heritage Journal
مصادر مصادر القانون الدولي في الألفية الثانية ق.م (أواخر عصر البرونز)
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 In the second millennium BC, the international community change at the ancient Near East, There has been a significant developments with the appearance of five kingdoms (Babylon, Assyria, Mitanni, Egypt, and Hatti) called themselves the (Great Powers) and their kings named (Great King), and Correspondence among themselves on behalf of (the brothers),  to differentiate themselves from the small kingdoms Minor of them.

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Publication Date
Sun Jan 13 2019
Journal Name
Arab Science Heritage Journal
سياسة النبي محمد (ص) الحكيمة في معالجة أحداث غزوة بني المصطلق
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 تعد دراسة التراث العلمي العربي من الدراسات التي تلقي الضوء على التطور التاريخي للعلوم العربية وما أنجزته العقلية العربية في هذا الميدان للمدة التاريخية التي ابتدأت بعصر صدر الإسلام وانتهت بالخلافة ويرى الكثير من العلماء سواء كان

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Publication Date
Tue Oct 05 2021
Journal Name
Arab Science Heritage Journal
مصنفات المؤرخ الاستاذ الدكتور عبد الله الفياض في تاريخ الحضارة الإسلامية
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The historian, Professor Dr. Abdullah Al-Fayyad, left a huge legacy of knowledge product that scholars and stakeholders benefited from in the field of Islamic historical and modern studies,

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Publication Date
Wed Jun 01 2011
Journal Name
Journal Of The College Of Languages (jcl)
توظيف التراث واللون في روايتي نبوءة فرعون وشاي العروس لميسلون هادي
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The novel in its construction depends on set of life elements that is employed by the writer or the novelist to create a convincing world that resemble the real life world and as the novel is going toward experimentation and employing modern phenomenon we find the novelist tends to take advantage from the most realistic details to achieve the required convincing state through serious situations and the novelist Maysaloun Hadi depended in writing her novels on creating tight relations between the things and the elements that has inspired her which are mostly from the environment and from reality , as an example of these elements is the old inherited traditions that distinguish Iraq society as this element is a very important point in Iraq

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Publication Date
Wed Jun 01 2016
Journal Name
Journal Of The College Of Languages (jcl)
BARBARA : structure et signification Étude analytique du langage prévertien à travers son poème Barbara
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Cette recherche étudie les structures composant Barbara, un poème de Jacques Prévert pour mettre en valeur la particularité de ce langage. Nous avons d'abord, dissocié ces structures, en : structure thématique, actancielle, syntaxico-énonciative, sémantique, formelle et finalement spacio-temporelle en vue de les analyser minutieusement. Le poète a adopté pour les thèmes : souvenir, nostalgie et guerre, un langage simple et une syntaxe incomplexe. L'usage du lexique et des figures de style célèbrent ces thèmes. La forme, la versification et la sonorité approfondissent ces images et renforcent ce langage. Ce poème dépend des phrases simples et variées : affirmative, interrogative, exclamative qui s'orientent vers des acte

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Publication Date
Mon Dec 01 2008
Journal Name
Journal Of Economics And Administrative Sciences
ستراتيجيات ردم الفجوة الرقمية في دول الاسكوا – مع إشارة خاصة للعراق-
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إن التغيرات السريعة والبعيدة المدى في تكنولوجيا المعلومات القائمة على أساس الالكترونيات الدقيقة تساعد في حدوث تحول في صورة الاقتصاد العالمي، وكذلك تساعد في تغيير المزايا التنافسية للبلدان، وربط المؤسسات البعيدة ببعضها البعض، ونشر الخدمات المالية على نطاق عالمي، وكذلك إثارة مشكلات جديدة او العكس فتح فرص جديدة أمام تنمية ونمو أفقر البلدان .

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Publication Date
Sun Dec 02 2018
Journal Name
Arab Science Heritage Journal
المنهج المنهج القرآني في تربية الأبناء بالحوار ( دراسة تفسيرية ـــ موضوعية )
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Quran orders and commandments and principles, has avenged children, their status and dearest, and saved their lives, which reached ill before Islam, and filled the hearts of the fathers and mothers for their love, but to make them embellish life.

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