Preferred Language
Articles
/
bsj-6431
Predictive Significance of Interleukins 17A and 33 in Risk of Relapsing–Remitting Multiple Sclerosis
...Show More Authors

Cytokines are signaling molecules between inflammatory cells that play a significant role in the pathogenesis of a disease. Among these cytokines are interleukins (ILs) 17A and 33, and accordingly, the current case-control study sought to investigate the role of each of the two cytokines in the risk of developing multiple sclerosis (MS). Sixty-eight relapsing-remitting MS (RRMS) Iraqi patients and twenty healthy individuals (control group) were enrolled. Enzyme linked immunosorbent assay (ELISA) kits were used to determine serum levels of IL-17A and IL-33. Results revealed that IL-17A and IL-33 levels were significantly higher in MS patients than in controls (14.1 ± 4.5 vs. 7.5 ± 3.8 pg/mL; p < 0.001 and 65.3 ± 16.3 vs. 49.3 ± 20.0 pg/mL; p < 0.001, respectively). Receiver operating characteristic (ROC) curve analysis demonstrated that IL-17A was a very good predictor of MS (area under curve [AUC] = 0.869; 95% CI = 0.779 - 0.960; p < 0.001; cut-off value = 10.2 pg/mL; sensitivity = 80.8%; specificity = 75.0%). A similar prediction was presented by IL-33, but the AUC value was lower (AUC = 0.762; 95% CI = 0.63 - 0.89; p < 0.001; cut-off value = 56.4 pg/mL; sensitivity = 70.6%; specificity = 70.0%). Multinomial logistic regression analysis confirmed the significance of IL-17A and IL-33 in MS risk, and under three models of analysis, the estimated odds ratios for IL-17A (1.50, 1.49 and 1.50, respectively) and IL-33 (1.05, 1.05 and 1.06) were above 1.0. Patients stratified by gender (male and female), expanded disability status scale (EDSS: < 3 and ≥ 3) or medication (pre- and post-medication) showed no significant differences in serum levels of IL-17A and IL-33 for each stratum. However, with regard to response to medication, it was found that responding patients showed significantly higher levels of IL-33 than non-responders (70.9 ± 12.2 vs. 57.2 ± 18.2 pg/mL; p = 0.018). This difference was not observed when considering IL-17A. Pearson correlation analysis between IL-17A and IL-33 revealed that both cytokines were not significantly correlated. In conclusion, the study indicated that IL-17A and IL-33 were up-regulated in serum of MS patients, and this up-regulation was not influenced by age, gender, EDSS or medication status, but the elevated level of IL-33 was more pronounced in patients who responded to medication.

Scopus Clarivate Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Wed Feb 06 2019
Journal Name
Journal Of The College Of Education For Women
الأراضي المفتوحة صلحاً في عصر الرسول والخلفاء الراشدین
...Show More Authors

Islam has paid great deal of attention to land issue where has been
considered most resources for providing Muslims with water and food and
building on that we notice that the Islamic government worked hardly to give
attention ton the land especially newly included under control of Muslims
especially that they had got with out fighting or bloodshed but had been
included via reconciliation with the landlords so the Muslims had share in that
would be taken either in cash or in materials in a value would be differentiated
following several issues like type of harvest and method of watering the land
and religion of the landlords.
So Muslims had listed laws and rules that enable them typical investment
for that l

... Show More
View Publication Preview PDF
Publication Date
Mon Apr 04 2022
Journal Name
Journal Of Educational And Psychological Researches
The Morals Strategies from Sunnah Depending
...Show More Authors

The study aims at elicitation the morals strategies from sunnah depending on the analytic-qualitative method. It revealed a comprehensive integrated system of creative strategies to improve morals. It was categorized into three areas: cognitive strategies, affective strategies, and some strategies based on self-initiative and practice. The researcher recommended that teachers and educators should employ these effective strategies in the process of moral guidance for the Muslim generation. He also recommended that researchers should put more effort to do more In-depth qualitative studies, which must be directed to establish the origin of different education strategies from the Holy Qur’an, the Sunnah, and Muslim scholars’ legacy.

View Publication Preview PDF
Publication Date
Sun Apr 28 2019
Journal Name
Arab Science Heritage Journal
الاراء الآراء والمعتقدات والتسميات الشعبية في مناخ العراق
...Show More Authors

This research aims to present a range of views and beliefs about the climate that have prevailed spontaneously in the Iraqi society and, whether agricultural or Bedouin communities and even popular communities within cities.

View Publication Preview PDF
Publication Date
Sun Jan 01 2012
Journal Name
Political Sciences Journal
دور شبكات التواصل الاجتماعي في ثورات الربيع العربي
...Show More Authors

دور شبكات التواصل الاجتماعي في ثورات الربيع العربي

View Publication Preview PDF
Crossref (3)
Crossref
Publication Date
Sun Oct 21 2018
Journal Name
Journal Of Planner And Development
التمكين الإقتصادي للمرأة الريفية ودورها في التنمية المستدامة
...Show More Authors

View Publication Preview PDF
Publication Date
Sat Mar 01 2014
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
دور محاسبة التكاليف في إبلاغ الإدارة بتكاليف الجودة
...Show More Authors

Due to the great technical developments in the field of informational knowledge, technological and productive changes and intense competition among institutes in the era of globalization, focus of these institutes on the notion of total quality management has been increased. Quality costs have represented an essential ratio of the production costs, a matter that requires preparing information about these costs, Because of that, the need for preparation and availability of accounting information system to measure and prove these costs has been emerged.

        The descriptive analytic method has been used here to answer the questions raised in this study. Among the results that have been reached

... Show More
View Publication Preview PDF
Crossref
Publication Date
Sun Mar 26 2023
Journal Name
Arab Science Heritage Journal
التعبير الاصطلاحي في آثار ابن المقفع- دراسة دلالية
...Show More Authors

Each of the languages ​​possesses a set of phenomena that researchers in its sciences should stop at to explain the secrets of this language, including the phenomenon of idiomatic expression. Perhaps this phenomenon may constitute an obstacle to non-native speakers of the language or even the native speakers themselves. The Arabic language is full of these expressions, Which needs us to dedicate its own studies to it so that we can collect it in a dictionary that includes and collects it with explanation and interpretation of its semantics

View Publication Preview PDF
Publication Date
Tue Jul 01 2008
Journal Name
Journal Of Educational And Psychological Researches
أثر أسلوب المناقشة في التوصل الى الدلالة الأدبية
...Show More Authors

تعد اللغة العربية العامة من المواد التي تدرسها الطالبات في الصف الأول في كل أقسام كلية التربية للبنات، وقد لاحظ الباحث إن الطالبات يفتقرن الى التعرف الى معاني كثير من الكلمات التي ترد في المقطوعات الأدبية الشعرية منها والنثرية التي يقدمها أستاذ المادة، وبما إن وقت المحاضرة محدود فأنه لا يسمح بالتعرف الى أفكار الطالبات حول معاني هذه الكلمات وقد يضطر الأستاذ أخيرا الى تقديم المعاني جاهزة للطالبات من اجل

... Show More
View Publication Preview PDF
Publication Date
Tue Dec 11 2018
Journal Name
Arab Science Heritage Journal
الفتح الفتح العربي الاسلامي واثره في المجتمع الفارسي
...Show More Authors

      The Islamic conquest for Persian country had the program of the civil and intelegical movement for the human

View Publication Preview PDF
Publication Date
Sun Jun 01 2008
Journal Name
Journal Of The College Of Languages (jcl)
הדמות הספורית בספור ה " שבוי " של ( ס' יזהר ) מאת ח'אלד ח'ירי חוסיו אלג'נבי
...Show More Authors

נסיון השביה בספרות המלחמה העברית יותר מביעה למרחק בסיכולוגי אצל הלוחם העברי ,
אני מעמד מול הנושא הזה , כי אני כותב בהמחקר הזה נסיון השבוי והשפעתו בציור הדמות אצל
הסופר '' יזהר סמילנסקי ) 1916 – 2006 ( " , סופר עברי יליד ישראל , נודע בכינוי תספרותי '' ס .
יזהר " מחשובי היצורים בספרות דור הפלמ''ח בפרט ובספרות העברית והכללית . חתן פרס ישראל
לספרות לשנת ) 1959 ( – כידד הגשם דמות ה '' אני '' וה '' אנחנו '' לגלה את ספל השבוי היחיד כ

... Show More
View Publication Preview PDF