Zerumbone is a well-known compound having anti-cancer, anti-ulcer, anti-inflammatory and anti-hyperglycemic effects. During its use for the disease treatment, the membrane of erythrocyte can be affected by consumption of this bioactive compound. The current study was the first report of investigation of the hemolytic activities on human erythrocytes and cytotoxic profile of zerumbone. The toxicity of zerumbone on human erythrocytes was determined by in vitro hemolytic assay. Brine shrimp lethality assay was used to evaluate the cytotoxic effect of zerumbone at concentrations 10, 100 and 1000 μg/mL. The human erythrocyte test showed no significant toxicity at low concentrations, whereas hemolytic effect was amplified up to 17.5 % at the highest concentration. The half lethal concentration (LC50) value of zerumbone against brine shrimp was less than 1000 µg /mL (LC50=190 µg/ml) showing the significant toxic nature of this compound. These results provide a baseline in terms of the toxicity of therapeutic formulations from this compound to membrane erythrocytes with a great attention to the highest concentrations, which paves promise for drug development.
מחקר זה בוחן את התפתחות הדימוי של ערבים בספרות הישראלית דרך עבודותיהם של אלי עמיר ודורית רביניאן שני סופרים חשובים שסיפוריהם מאתגרים סטריאוטיפים שוררים ומרחיבים את ההבנה התרבותית הניתוח הממוקם במסגרת הספרות המזרחית עוקב אחר האופן שבו דמויות ערביות עוברות מדמויות שוליים לאנשים מורכבים ומעודנים המשקפים שינויים סוציו פוליטיים רחבים יותר על ידי השוואת חקר הזהות והעקירה של עמיר בסביבה היהודית בבגדד לבין
The research aims at the following:
- Identifying the level of internal quantity efficiency in Medical colleges, University of Baghdad by determining the level of productivity for one group for the total batch according to sex variable (males and females). Procedures of the study
The researcher used the descriptive and analytical method has been used by following them up enhanced by flow indicators of students for one session depending on special statistical data analyss .
The results are as follows:
- The Faculty of Medicine were higher productivity scholarships for one year and two years of schooling, as well as the highest in the efficiency of the Faculty o
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إنها وصف واقعي أو خيالي لأفعال تهدف إلى ترفيه أو تثقيف المستمع أو القارئ. (روبرت لويس ستيفنسون) يقول أحد رواد سرد القصص البارزين: هناك ثلاث طرق فقط لكتابة قصة: إما أن يختار الكاتب حبكة ثم يجعل الشخصيات تتناسب معها، أو أن يختار شخصية ويختار الأحداث والمواقف التي تُطور الحبكة. الحبكة هي التصميم أو المنطق أو البنية لنوع معين من الخطاب الذي يُطور وحداته من خلال تسلسل زمني. وهي تُعطي القصة...