There are many animal models for polycystic ovary (PCO); using exogenous testosterone enanthate is one of the methods of induction of these models. However, induction of insulin resistance should also be studied in the modeling technics. Therefore, the present study aims to investigate the expression of insulin receptor substrate (Irs)-2 mRNA in the liver tissue of rat PCO model. Nineteen Wistar rats were divided into three groups; (1) PCO modeling group (N =7) received daily 1.0 mg/100g testosterone enanthate solved in olive oil along with free access dextrose water 5%, (2) vehicle group (N =6), which handled like the PCO group, but did not receive testosterone enanthate, (3) control group (N =6) with standard care. All the animals were administered via intra-peritoneal injection for 14 days. Expression of Irs-2 mRNA was studied with real-time PCR and fold changes (FC) were reported. The average of expression in the control group was considered as the calibrator. About 13.4% expression reduction was found in the PCO group (FC =0.874, P-value =0.043). No significant reduction was found in the vehicle group (FC =0.951, P-value =0.076). However, analysis of variance did not show a significant difference between all the groups of study (P-value =0.085). The present model of PCO might induce insulin resistance at liver level with a low effect size via reduction in the mRNA expression of Irs-2. Study of the involved genes and molecules in other tissues of PCO animal models is suggested.
Considers births illegal for children (illegitimate) phenomenon of negative social phenomena in our society where it's dangerous and the superiority of gravity on other social phenomena Calanhrav, homelessness and other due to poor drainage energies and sexual dysfunction in the value system among its actors and is characterized by the absence of social conscience and a lack of morality and the weakness of the system human-reliance among others.
The morality is the obvious difference between humans and animals. Wade this to say social scientists, while human social animal they said no that he has morals and values do not exist in other organisms so well that births
... Show MoreThe principal components analysis is used in analyzing many economic and social phenomena; and one of them is related to a large group in our society who are the university instructors. This phenomenon is the delay occurred in getting university instructor to his next scientific title. And as the determination of the principal components number inside the principal components depends on using many methods, we have compared between three of these methods that are: (BARTLETT, SCREE DIAGRAM, JOLLIFFE).
We concluded that JOLLIFFE method was the best one in analyzing the studying phenomenon data among these three methods, we found the most distinguishing factors effecting on t
... Show MoreThe literature in general, such as the spanish literature as british literature presence lot of literary figures giant that managed its continuing work that leaves lasting impression and clear in all fields of literary world throughout history, among these writers giants can remind great writer spanish (Miguel de Cervantes) and the great british writer (William Shakespeare), this study is about them.
We can say that there are a lot of studies , works and gossip , whether literary or non- literary show how the close relationship that bound both Cervantes and William Shakespeare, although they did not meet personally never, it was not able to critics that the sweep of the differences and similarities that was between the two, becau
... Show MoreA lot of researchers and specialists in language sciences have been agreed that Arabic language is on of living languages never disappear and keep pace with innovation and the challenges of the age and evolution civilization i.e any development in it’s connotations doesn't tzopped it (melted
أن هذه الدراسة هي دراسة نظرية اهتمت بتقديم مدخل معاصر لمنظمات الأعمال، يمكن أن يعتمد علية من أجل تحقيق الريادة و البقاء. وذلك من خلال اعتماد مدخل الهدم الخلاق و تقديم أنموذج قادر على التفاعل مع البيئة بكل ما تقدمه من فرص وتحديات.
وتم تقسيم هذه الدراسة إلى ثلاثة مباحث،تناول المبحث الأول منهجية الدراسة. وبينما تناول المبحث الثاني توضيح مفهوم الهدم الخلاق والعناصر المكونة لهذا المدخل وأخيراً
... Show Moreتم التطرق إلى مفهومي الخجل والعنف الأسري لدى الفتيات ضعيفات السمع ومشكلة البحث تكمن بدراسة العنف الأسري لضعيفات السمع وعلاقته بالخجل ومعرفة ما يترتب عن ذلك بالنسبة للفتاة المراهقة ضعيفة السمع أثناء تعرضها للمعاملة السيئة وأثره على شخصيتها ، فالخجل هو نتيجة لأساليب التربية الخاطئة التي تعاني منها الفتاة ضعيفة السمع ، ويهدف البحث إلى التعرف على الخجل وعلاقته بالعنف الأسري لدى ضعيفات السمع في محافظة بغداد ، و
... Show Moreيعد الزمان عنصراً جمالياً مساهماً له القدرة على خلق المعنى والدلالة ، ومشاركاً في الاستراتيجية الحكائية إذ ينتقل من مجرد عنصر حكائي إلى محرض للمتلقي فهو زمان الإنسان الداخلي .
أولاً : مشكلة البحث :
أن مشكلة البحث تتمثل بوجود حاجة لتحسين الطرائق والأساليب المتبعة في التدريس ولذلك اتجهت البحوث في مجال التربية وعلم النفس إلى تحديد طرائق التدريس المناسبة لتطوير التفكير.
ومن هذه الأساليب الحديثة العصف الذهني بوصفها من اكثر الطرق التي قد تؤدي إلى تحفيز الطلبة وأثاره القدرات الإبداعية لديهم في حقول التربية والتعليم وا
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