There are many animal models for polycystic ovary (PCO); using exogenous testosterone enanthate is one of the methods of induction of these models. However, induction of insulin resistance should also be studied in the modeling technics. Therefore, the present study aims to investigate the expression of insulin receptor substrate (Irs)-2 mRNA in the liver tissue of rat PCO model. Nineteen Wistar rats were divided into three groups; (1) PCO modeling group (N =7) received daily 1.0 mg/100g testosterone enanthate solved in olive oil along with free access dextrose water 5%, (2) vehicle group (N =6), which handled like the PCO group, but did not receive testosterone enanthate, (3) control group (N =6) with standard care. All the animals were administered via intra-peritoneal injection for 14 days. Expression of Irs-2 mRNA was studied with real-time PCR and fold changes (FC) were reported. The average of expression in the control group was considered as the calibrator. About 13.4% expression reduction was found in the PCO group (FC =0.874, P-value =0.043). No significant reduction was found in the vehicle group (FC =0.951, P-value =0.076). However, analysis of variance did not show a significant difference between all the groups of study (P-value =0.085). The present model of PCO might induce insulin resistance at liver level with a low effect size via reduction in the mRNA expression of Irs-2. Study of the involved genes and molecules in other tissues of PCO animal models is suggested.
Developed technologies and complementary means for viewing theater through the ages, and they affected would improve and get better. Valsinogravea appeared to express a description and identification of existing in the theatrical space of lighting and decorative structure architecture, and the lighting of the elements that have contributed since ancient times in the process of the show, and played a significant role in strengthening the relationship between the recipient and actor and presentation theater as a whole scenes, working to broadcast a dramatic speech theatrical holds ideas and content and symbols and semantics affect the spectator of different age, particularly the child viewer, that little spectator who represent the
... Show MoreThe letters draw clear picture for what had happened in that time it was full of incidents .that incidents had began with the byzantine invation and persioan persecution .later on the Muslins managed to conquest Iraq and Persia .the muslims spread peace and security for the pupils of that area.
Ishuib manged to achieve peace and security to his adherence .he proved that he was one of those who were aunique persons. Because he did his beast to active and revive the general and special life to his adherence. He succeeded to organize the Christian relation ship with the muslims .
He wrote an agreement with muslims .he thought that this Islamic canquest was from allah to die done the mazdism. He said t
... Show MoreThis research discussed the freedom of Iraqi women in the thought of Dr. Nazeeha Al-Dulaimi.
Prophecy in general, and Muhammadism in particular, can not seem to go away from life, or lag behind it, because it was originally for reform. It can not succeed in achieving this reform. It has grown away from it, and its conditions have not caused it to vary and diversify. These conditions, from its origin to its tranquility, its stillness and its movements, are based on a wise divine workmanship and a strict divine planning that suits the performance of this personality
تتباين القراءة والكتابة من ناقد لآخر تبعا للموضوع الذي يتناوله، وطبيعة المادة، والمكونات المعرفية التي تؤسس فهمه، فمنهم الناقد التقليدي الذي يتبع السائد في نقده للمادة الفنية اما بالموافقة والتبني أو بالمغالطة والقدح، ومنهم الناقد المقلد الذي ينتخب اتجاها غربيا يرغب في تطبيقه على جزء من النصوص التي انتقاها، ومنهم الناقد الذي يتبع أفكاره ويدمجها مع النص ناقد مختلف يبحث في ما يذلل من قواعد، يحلل ويشرح وفقها
... Show Moreנסיון השביה בספרות המלחמה העברית יותר מביעה למרחק בסיכולוגי אצל הלוחם העברי ,
אני מעמד מול הנושא הזה , כי אני כותב בהמחקר הזה נסיון השבוי והשפעתו בציור הדמות אצל
הסופר '' יזהר סמילנסקי ) 1916 – 2006 ( " , סופר עברי יליד ישראל , נודע בכינוי תספרותי '' ס .
יזהר " מחשובי היצורים בספרות דור הפלמ''ח בפרט ובספרות העברית והכללית . חתן פרס ישראל
לספרות לשנת ) 1959 ( – כידד הגשם דמות ה '' אני '' וה '' אנחנו '' לגלה את ספל השבוי היחיד כ
LA TRANSGRESSION CHEZ RIMBAUD Lecture de I' aspect de Transgression dans Marine
По мнению ученых, исследующих современные деривационные процессы, „начиная со второй половины XX в., активизируются новые социолингвистические и коммуникативные факторы”, определяющие специфику современного словотворчества в ряде типологически близких славянских языков [Нещименко 2010: 39]. В результате возросшего влияния масс-медиа на коллективное сознание носителей языка, на существующий вербальный
... Show Moreاحتلت قضية غسيل الاموال أهمية كبيرة على الساحة الاقتصادية العالمية خلال الفترة الاخيرة إدراكا من المجتمع الدولي لأثارها السلبية على الاستقرار الاقتصادي و خاصة على الاستثمار المحلي و الدولي و لذلك يتزايد الاهتمام بها و سبل مواجهتها من قبل العديد من الدول و المنظمات الدولية و المراكز المالية الكبرى , حيث تهدد هذه الظاهرة الاقتصاد العالمي و خاصة اقتصاديات العالم النامي و من بينها الاقتصاديات العربية .
ان
... Show Moreيتناول البحث اثر عدم معرفة مرتكب الفعل الضار في المسؤولية المدنية من حيث اساسها واثرها