Ghrelin and leptin are hunger hormones related to type 2 diabetes mellitus (T2DM), and the pathogenesis of T2DM is the abnormality in insulin secretion and insulin resistance (IR). The aim of this study is to evaluate ghrelin and leptin concentrations in blood and to specify the relationship of these hormones as dependent variables with some biochemical and clinical measurements in T2DM patients. In this study, forty one T2DM and forty three non-diabetes mellitus (non-DM) subjects, aged between 40-60 years and with normal weight, were enrolled. Fasting serum ghrelin and leptin were estimated by enzyme-linked immunosorbent assay (ELISA). In our results ghrelin was significantly increased, and leptin was significantly decreased, in T2DM patients compared with non-DM subjects. Ghrelin was positively correlated with the fasting blood glucose (FBG) and IR, but inversely related to the insulin sensitivity (IS). Leptin was negatively correlated with mean arterial pressure (MAP), FBG, glycated hemoglobin (HbA1c), IR, low-density lipoprotein cholesterol, nitric oxide (NO), and alanine aminotransferase (ALT), as well as showed a linear correlation with IS and a strong dependence on sex. The area under the curve (AUC) value shows ghrelin and leptin as biomarkers for T2DM. In conclusion ghrelin and leptin hormones have predictive ability to predict T2DM, as they are significantly associated with IR, IS, free radicals, and lipid profile.
The organization and development of the irrigation system and agrarian reform in Iraq had an impact on the diversity of its methods and uses
It is important to study that the social circumstances in Alexandria through Mamluk era specially social life in Egypt specially in Alexandria which had describe as it was show change in opposite with other sides of life
The legal text in the language of civil law, constitutional law, language of judges, and legal profession is concerned with a legal language and words that are coherently significant
اشتهرت بغداد بمساجدها ومأذنها ذات الطراز المتميز في التصميم والشكل والحجم والبناء والزخرفة. ونتيجة للاحتلال المتكرر والغزو الاجبي والكوارث الطبيعية الاخرى فان معظم ابنيتها تعرضت للتدمير والاندثار ولم يبق الا القليل منها شاهدا
There was a huge role in the history of a muslim woman and several books have mentioned that politically or in religion and even scientifically and socially which leaded a lot of women to look up to these women who helped in keeping the religion just in the right form for other generations
Within connected speech, RP speakers tend to shorten stressed long vowels end diphthongs in pre. Forties consonants in the same syllable on the basis of complementary Distribution, i.e., the phonological environment decides the influence of the forties plosives and fricatives, as far as they are in find position preceded by stressed long vowels and diphthongs, or particular voiced consonants plus vowels. The Iraqi learners, then, face.
يتركز محور مشكلة البحث الحالي حول مفاهيم أساسية تعكس مكامن القوة في الشخصية الإنسانية وما لها من دور مؤثر على الواقع النفسي والمادي للفرد عموماً وهذه المفاهيم هي صلابة الشخصية، وتقدير الذات,ويتحدد مفهوم الصلابة من خلال مظاهر الشخصية وأسلوبها الذي تتميز به في التعامل مع الواقع وكيفية إدراكها وما تتمتع به من خبرات نفسية وتجارب حياتية داخلية تعكس مدى الوعي بالمستجدات الموقفية التي تصادفها
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An automatic text summarization system mimics how humans summarize by picking the most significant sentences in a source text. However, the complexities of the Arabic language have become challenging to obtain information quickly and effectively. The main disadvantage of the traditional approaches is that they are strictly constrained (especially for the Arabic language) by the accuracy of sentence feature functions, weighting schemes, and similarity calculations. On the other hand, the meta-heuristic search approaches have a feature tha
... Show Moreمشكلة البحث واهميته :
يعد الغضب من المظاهر الانفعالية الشائعة في مرحلة الطفولة المبكرة وذلك بسبب كثرة المواقف المثيرة لغضب الطفل في هذه المرحلة ، كما ان الطفل في هذه المرحلة سرعان ما يكتفي في كثير من الاحيان بان غضبه وبكائه طريقة سهلة للوصول الى ما يريد . ويعد المختصون في هذا المجال ، بان نوبات غضب الاطفال ، هي شيء عام طبيعي عند جميع الاطفال ، لكن عندما تكون نوبات عنيفة
... Show Moreالعلوم السياسية في العراق بداياتها ، نشأتها ، تطورها ، ومفرداتها التدريسية