Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
Abstract:
the system of Administrative Control in organizations meets the need to check on the optimal use and proper resources and conservation to achieve the objectives sought by the organization, hence the system of Administrative Control is part of the overall system in any organization that has undergone evolution always to be able to keep up with progress in the development of other sciences, and that the growth of coherence between subordinates in the organization means the ability to influence the opinions, ideas and attitudes to change it for directions the organization and its values and this is reflected positively on the coherence of the organization, the researcher interest of the imp
Analytical Hierarchy Process (AHP) belongs to the family of Multiple Criteria Decision Making (MCDM) and has, recently, received a wide popularity in decision making regarding supplier selection. The objective of this study is to apply the methodology of AHP on selecting suppliers to supply materials for the Geological Survey and Mining Company (GSMC). Criteria for rating the suppliers and pairwise comparisons were identified by the members of the Tenders Analysis Committee (TAC). In order to judge the internal validity of the AHP, it was applied manually on a sample of fourteen tenders that were analyzed and executed between 2004-2007, then an interactive computerized package was developed
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The public budget in Iraq is still prepared according to the traditional base that allocates the amounts of budget the current year based on the budget of previous year with an increase in estimations with random proportions without connecting the input (financial, human resources and asset )with their output (quantitatively and qualitatively)this caused waste and lose in the available resources therefore the output of budget showed be adapted is such a way that achieving connection between its input and output and to be appropriate with the organizational structure of the state without intrinsic change in its work .this may be realized by adopting the accounting of
... Show Moreأظهرت الدراسات الاعلامية واللغوية السابقة التي تناولت واقع اللغة العربية في شبكات التواصل الاجتماعي ثلاث مشكلات لغوية في هذا الميدان الأولى تمثلت بالثنائية اللغوية التي تجلت باستعمال عدد من مفردات اللغة الانكليزية الى جانب اللغة العربية ، والثانية تمثلت بالإزدواجية اللغوية التي تجلت في مزاحمة اللهجة المحلية للفصحى في النصوص المكتوبة ، والثالثة ارتبطت بمشكلة الضعف اللغوي في مستويات اللغة الكتابية والمع
... Show MoreChapter One – introduction
Nations managed today to achieve progress in the field of modern technology. Science has changed many beliefs and trendiness that people have held for long time, skills and scientific thinking developed, and made scientific observation and experiment replace narration and taking from others. That is attributed to examining the educational systems searching for the locations of defect, and shortage.
In the light of educational modernizations, many models of teaching incliuding a model for social tracing attributed to Herbart Thelen, which is a model to develop skills of social participation in the democratic process (Al-Khawalda,1993,335).
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This study is considerated one of many Studies above the standing of
the Islamic Arab nation which was chosen by God from other nations all over
the world . Some of these nations used to come to the Arab nation to take
whatever useful for them from the beginning of history till now . The
researcher deals in this study with a French artist who is well-know as
August Renoir . He traveled to Algeria and lived there . He was
influenced by the Islamic culture.
The study include. from chapter . chapter one deals with the framework of
programming (out line ) . Chapter two deals with the theoretical framework .
It includes five sections. Deals with the Islamic drawings(Arabesque) . section
three deals w
The research aims to diagnose the level of reflection of uncertainty management strategies (Ignoring uncertainty, knowledge generation , interaction , coping) managing of Organizational change strategies (power coercive, rational empirical, Normative reductive) to the importance of the two subjects and the importance of the expected results has been selected sample size (65) managers from Zain , Asia Cell Telecommunication (32 Zain and 33 company Asia),which alignment for the such a study being heavily dependent on the certainty or uncertainty subject . The researchers are attain there is the effect of uncertainty management strategies in Organizational change management strategies on the overall level in the two companies but have tended t
... Show Moreللدراسات التاريخية أهميتها ولاسيما دراسة المؤلفات الذي يعطينا صورة كاملة عن تطور الواقع التاريخي للمرحلة التي عاصرها المؤلف وتكتب دراسة الشخصيات العلمية طابعاً خاصاً ومهم يدفعنا إلى التعريف بالمؤرخ ومنهجه في الكتاب والموارد التي استقى معلوماتهِ منها .