This work studies the role of serum apelin-36 and Glutathione S-transferases (GST) activity in association with the hormonal, metabolic profiles and their link to the risk of cardiovascular disease (CVD) in healthy and patients' ladies with polycystic ovary syndrome (PCOS). A total of fifty-four (PCOS) patients and thirty-one healthy woman as a control have been studied. The PCOS patients were subdivided on the basis of body-mass-index (BMI), into 2-subgroups (the first group was obese-PCOS with BMI ≥ 30 and the second group was non-obese PCOS MBI<30). Fasting-insulin-levels and Lipid-profile, Homeostatic-model assessment-of-insulin-resistance (HOMA-IR), follicle-stimulating-hormone (FSH), luteinizing-hormone (LH), testosterone and serum Apelin-36 (AP-36) levels, GST-Activity were done for all groups. PCO patients showed higher concentricity of apelin-36 than healthy (160.43 ±20.81 (pg/ml) versus 85.49 ± 17.85 (pg/ml), P=0.008),while GST-activity decreased in PCOS patients and was higher in the control (7.99 ± 1.19(IU/L)versus 12.96 ±1.90(IU/L)respectively,with a P-value=0.022). Apelin-36 levels are directly interrelated with BMI and Very-low-density-lipoprotein (VLDL) in PCOS patients, but GST-activity levels correlated significantly negatively with (BMI) in PCOS patients. Moreover, obese-PCOS patients show increased AP-36 levels more than non-obese PCOS (185.76± 92.0(pg/ml) versus 123.59±27.65 (pg/ml), P=0.127) respectively, whilst the GST-activity was exhibited to be lower in obese-PCO patients more than in non-obese PCOS (6.99 ± 1.4(IU/L) versus 9.44 ± 2.0(IU/L), P=0.102). The data showed that AP-36 level is negatively associated with GST-activity in PCOS patients. AP-36 isn't legitimately ensured in the pathogenesis of PCO disorder, yet it may be included as an adipokine that is influenced by BMI. The oxidants increased because of the highly levels of VLDL and the lower in the activities of antioxidant, that may be a response to higher levels of oxidative stress. A decrease in the antioxidant capacity and an increase in AP-36 levels leads to an increased the risk of cardiovascular disease in PCOS patients.
سياسات الاصلاح النقدي في جمهورية الصين الشعبية
الفيدرالية : نظرة في منطلقاتها الفكرية وآفاقها المستقبلية
Academic libraries characterized from other libraries in the groups of literacy acquired, and
ways to retrieve this information, where it is supposed supply of various combinations of traditional
sources, electronic information, such as books and references, maps and indexes, CD-ROMs and
service-line and so on, via electronic mediator or via the Internet instead of the mediator paper. The
digital technology has changed the way you work by academic libraries, where confined to the
primary mission of these libraries to provide prompt services to the needs of researchers, professors
and students, and the provision of reading different materials, including electronic sources that
support the curriculum and research in el
Quran is a basic reference of production it is as a source to all sciences, Ayat of Quran would mention the importance of benefits of animals. Quran contain full surrat named in animal names as Al-Baqara that is to clarify its benefits and importance in human’s life.
Throughout the ages, a number of natural and human disasters have
occurred in the Islamic world,
اهتمت دول العالم بدول الساحل الإفريقي لمِا عرفته من ثروات معدنية كثيره فيها، وإن دول الساحل الإفريقي تقع في وسط القارة الإفريقية وإنها تمتد من البحر الأحمر أي مطلة على البحر الأحمر مما يجعلها ذات أهمية ملاحية. والذي زاد في أهميتها مواردها الطبيعية إذ أنها ذات موارد اقتصادية متنوعة وكثيرة لا سيما وأنها قليلة الاستهلاك لهذه الموارد فهذا أدى إلى أهتمام الدول التي يكثر استهلاكها لهذه الموارد فيها، ومن هذه الموا
... Show Moreالآت الاطفال الموسيقية الشعبية والتقليدية في التربية
Dans le romantisme et ses textes, il est important de mentionner qu'il n'existe qu'un seul thème romantique qui est l'amour, mais assez pour avoir fait du XIXème siècle, une révolution du texte romantique. L'amour consiste à la réduction de l'univers, à un seul être, puis la dilatation de ce seul être, voilà l'amour. cet amour passionnel n'est qu'un arrangement froid et réfléchi excluant d'emblée l'exaltation des sentiments. Néanmoins, cet amour passionnel peut être brutal. quant à la mort, dans le drame romantique, l'amour et la mort sont liés. Beaucoup d'histoires d'amour finissent le plus souvent par
... Show MoreThis research is an attempt to prove the scientific tendency in the Islamic philosophical heritage through a review of the most important ideas of intellectual and philosophical theories brought by the philosophers of this