The biomarker significance of three chemokines (CXCL8, CXCL10 and CXCL16) was evaluated in sera of 45 breast cancer (BC) and 28 benign breast lesion (BBL) patients, as well as 20 control women. Clinical stage and tumor expression of estrogen (ER), progesterone (PgR) and human epidermal growth factor receptor-2 (HER-2) receptors were considered in this evaluation. The results demonstrated that CXCL8, CXCL10 and CXCL16 showed a significant increased median in BC and BBL patients compared to control (CXCL8: 47.3 and 25.7 vs. 15.0; CXCL10: 37.6 and 30.7 vs. 13.1; CXCL16; 27.9 and 25.2 vs. 19.2 pg/ml, respectively). The increased levels of CXCL8 and CXCL16 were more pronounced in triple-negative and HER-2 positive patients, respectively. Binary logistic regression analysis revealed that CXCL8 was a significant predictor of BC, and such prediction was more depicted in triple-negative patients. The receiver operating characteristic analysis also revealed that CXCL8 recorded an area under curve of 0.998 in BC patients. In conclusion, CXCL8 is a potential biomarker for BC, especially when ER, PgR and HER-2 expression is considered. In this context, the predictive significance of CXCL8 in influencing BC progression is suggested in triple-negative patients.
فاعلية تطبيق اسلوب المهام الدراسية في اتقان اللغة الاسبانية للطلبة العراقيين.
Some great families in England had competed for the sake of getting authority and power in England.
This competition turned to be a bloody civil war which extended till 1455 and ended with the victory of Henry Tudor whose judgment in England started from 28th of August 1458, consequently a new dynast which is known as (the Tudor)has established
The importance of teaching methods and procedures comes from the nature and significance of the questions raised inside the classroom. That is, because questions, in fact, are the means of communication and interaction in the class situation. Therefore they are considered as indispensible elements in any teaching approach. Furthermore, it is noticeable that the majority of teachers fail in using them, for questions are often casted spontaneously and without pre-planning. Hence, a delay may occur in realizing the pre-set objectives, and let alone the dominance of stereotyped questions, especially when the teachers focus on a type of question which can be directly answered from the text-book.
&nb
... Show MoreIt is summarized that Abu-Baker Al-Soly is one of Arabic Muslim scientists who had special style in literary writing specifically in sciences and knowledge that had depended on the encyclopedia culture gained from various fields of science , this means that he was an individual who had participated to characterize features of Islamic –Arabic history enhanced the rules of it , this matter would encourage us to know the method and style of writing in the field of intellectual life in which the writer depended on the procedures direction of scientists that he lived in the Abbasid era .
It is axiomatical that the narrative prospective is profoundly significant to the writer who intends to commence his sketch of projected novel. It is the pillar of comprehensive absorbing as the writer should commit himself to circular his own concepts to the reader of his narrative characters.
The dilemma of plot-perception is a twofold aspect; partly offers the question: what is the authors stand in regard to his characters? And: what is the aim of this theme? These correlative questions are inseparable since the reader who wishes
... Show Moreيُعد الوزن الاقتصادي للهند من أبرز عناصر قوتها الجيوسياسية، إذ تُصنف الهند ضمن أكبر الاقتصادات عالميًا، مدعومة بحجم سكاني ضخم وسوق استهلاكي واسع ونمو متسارع في قطاعات الصناعة والخدمات والتكنولوجيا. حقق الاقتصاد الهندي نموًا قويًا خلال السنوات الأخيرة، مع استمرار معدل نمو الناتج المحلي ضمن نطاق مرتفع مقارنة بكبرى الاقتصادات العالمية، حيث تتوقع عدة مؤسسات دولية نموًا يقارب 6.3–7% خلال 2026–2027.
مايزال انتاج المياه في محافظات الفرات الاوسط بشكل خاص و العراق بشكل عام نواجه تحديات كبرىالتي ادت الى تردي انتاج المياه و استهلاكها
لقد كان الألفون جزءاً من اللوحة الفونيميّة، وهو جزء صوتيّ لا يُغيّر المعنى، مع أنّه تغيّر صوتيّ فونيميّ، له أنواعه المتمثّلة بالهمس والجهر، والنّبر، والاختلاس، والإخفاء، والإشمام، والإقلاب، والتّماس، والقلب، وهذه الأنواع كانت مؤشّرات تنغيميّة صوتيّة نالت حظّاً وافراً لدى باحثي الأصوات وعلماء التّجويد، وكان لها شروطها ومواقعها وأثرها في المخاطِب والمخاطَب، لأنّ كلّ صوت يخرج من متكلّم ليصل إلى سامع يؤثر ب
... Show MoreCompanies compete greatly with each other today, so they need to focus on innovation to develop their products and make them competitive. Lean product development is the ideal way to develop product, foster innovation, maximize value, and reduce time. Set-Based Concurrent Engineering (SBCE) is an approved lean product improvement mechanism that builds on the creation of a number of alternative designs at the subsystem level. These designs are simultaneously improved and tested, and the weaker choices are removed gradually until the optimum solution is reached finally. SBCE implementations have been extensively performed in the automotive industry and there are a few case studies in the aerospace industry. This research describe the use o
... Show Moreتناول هذا البحث الدور الحيوي الذي تؤديه المراكز البحثية في دعم القضايا الاجتماعية، مع التركيز على مركز دراسات المرأة في جامعة بغداد كنموذج تطبيقي. يوضح الباحث أن هذه المراكز لا تقتصر على إنتاج المعرفة النظرية، بل تسهم بشكل مباشر في معالجة التحديات المجتمعية، من خلال تقديم رؤى تحليلية ومقترحات عملية لصناع القرار. كما ويسلط الضوء على مساهمة مركز دراسات المرأة في تعزيز المشاركة السياسية للمرأة العراقية، خاصة
... Show More