The biomarker significance of three chemokines (CXCL8, CXCL10 and CXCL16) was evaluated in sera of 45 breast cancer (BC) and 28 benign breast lesion (BBL) patients, as well as 20 control women. Clinical stage and tumor expression of estrogen (ER), progesterone (PgR) and human epidermal growth factor receptor-2 (HER-2) receptors were considered in this evaluation. The results demonstrated that CXCL8, CXCL10 and CXCL16 showed a significant increased median in BC and BBL patients compared to control (CXCL8: 47.3 and 25.7 vs. 15.0; CXCL10: 37.6 and 30.7 vs. 13.1; CXCL16; 27.9 and 25.2 vs. 19.2 pg/ml, respectively). The increased levels of CXCL8 and CXCL16 were more pronounced in triple-negative and HER-2 positive patients, respectively. Binary logistic regression analysis revealed that CXCL8 was a significant predictor of BC, and such prediction was more depicted in triple-negative patients. The receiver operating characteristic analysis also revealed that CXCL8 recorded an area under curve of 0.998 in BC patients. In conclusion, CXCL8 is a potential biomarker for BC, especially when ER, PgR and HER-2 expression is considered. In this context, the predictive significance of CXCL8 in influencing BC progression is suggested in triple-negative patients.
It is known that the distinguished scholar and writers in any kind of science leave an important impact on those who come after them, so they are an indispensable source in that science that draws from them who is later in time than them, and this is what we have seen in this research; The scholar Muhammad bin Shuraih al-Ra’ini (d.476 AH) and his book (Al-Kafi in the Seven Readings) were admired by everyone who wrote about the readings after him. The great scholars of the readings, such as Ibn al-Bathish (d. 540 AH), Ibn al-Jazari (d. 833 AH), and Ibn al-Banna’ did not dispense with him. (d.1117 AH) in terms of reading, isnad, and the way of narration, their books were full of men
... Show MoreThe book Tabaqat al-Faqih by Abu Ishaq al-Shirazi (d. 174 AH / 4801 CE) is considered one of the important sources and dates back to the fifth century AH
This study took place during the first semester 2006-2007 at the same time the Jordanian universities were getting ready to receive the American team sent by QAA to check out the defects in the educational system of these universities, the researchers concentrated on the practical study more the than the theoretical study, the theoretical study covered the understanding of quality & quality in education as well as the authorities responsible for the regulations & quality standards such as QAA ,JMOHE, Al-Hussein Fund For Excellence. The main problem which faced the Jordanian private universities was the conflict in objectives between profitability & qualitative output which was because of lack of long tem strategic plann
... Show Moreاثر المحددات الخارجية والداخلية في بناء الدولة العراقية
Si Alfonso x el sabio y la Escuela de Traductores de Toledo habia hecho del castellana una lengua apta para la expresión cientifica, fue Pablo Neruda quien aplicó su sentido artistico para crear una poesia amorosa de caracter lileraria. Por lo tanto, pocos poetas han llegado ton populares come. Pablo Neruda, en el mismg tiempo: se comsidera esccitor de una abundante producción literaria ne sólo en su ciudad natal de (Chile), Sino ha sida uno de los padres de la poesia hispanoamericana contemporónea. Ademas la influencia que ejerció en el grupo de poetas de la Generación del 27, con los que empezó a relacionarse durante su estancia en Madrid, fue decisiva también para la poesia espańola. Esa era la razon principal que me hizo pe
... Show Moreتعد دراسة الموارد الماءية السطحية من المواضيع المهمة وذلك لكثرة السكان وازدهار استهلاك الإنسان لمياه الشرب وفي مجال الشرب والزراعة والصناعة وكثرة الملوثات في المياه وكيفية معالجتها
The social support is considered one of the most important constituents of
society and the one which can ensure its unity.
The resources of social support are different accordind to the variety and
the multiplication of the net – work of the social relationships that are
established among the individuals. The importance of this variable is evident
in the emolional adaptation and the mental health as well as its role in mitigating of the illness threating and in accelerating the recovery. social support can enhance the individuals ability to tolerate and face the emotional
and physical problems in the time of cris and stressful life conditions.
The most important results are shown as follows :
1- It was
قسّم الباحث الشخصيات في هذ ا البحث إلى أقسام: اإيجابية والسلبية
والسطحية...ثم تطرقا إل خصوصياتها النفسيّة وبينا مقصود الكاتبة، وتطرّقا إلی الغزو
الثقافي الغربي ،
مشكلة البحث واهميته:-
اخذ موضوع العولمة قدراً وافياً من الاهتمام سواء على المستوى الاكاديمي او على مستوى اجهزة الاعلام والرأي العام ومختلف التيارات السياسية والاقتصادية والاجتماعية ، فلا يخلو أي لقاء اقتصادي او سياسي او اجتماعي من الحديث عن العولمة اذ نشرت العديد من الابحاث والدراسات وعقدت الكثير من الندوات والمؤتمرات لدراسة العولمة وبيان اثارها ولعل ذل
... Show Moreان تقدير مسؤولية المحاسب في تصميم نظام المعلومات المحاسبي من منظور تاريخي سبقت استخدام الحاسوب كأداة معلوماتية للاعمال، لما له من رؤيا بالتطورات الرئيسية لنظام المعلومات والتي اهمها تحديد متطلبات مستخدمي المعلومات وتعيين مضمون وشكل مخرجات النظام من التقارير وتحديد مصادر البيانات وانتقاء القواعد المحاسبية الملائمة فضلاً عن الرقابة الضرورية لتكامل وفاعلية النظام.
ان النظم المحاسبية التقليدية غالبا
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