The biomarker significance of three chemokines (CXCL8, CXCL10 and CXCL16) was evaluated in sera of 45 breast cancer (BC) and 28 benign breast lesion (BBL) patients, as well as 20 control women. Clinical stage and tumor expression of estrogen (ER), progesterone (PgR) and human epidermal growth factor receptor-2 (HER-2) receptors were considered in this evaluation. The results demonstrated that CXCL8, CXCL10 and CXCL16 showed a significant increased median in BC and BBL patients compared to control (CXCL8: 47.3 and 25.7 vs. 15.0; CXCL10: 37.6 and 30.7 vs. 13.1; CXCL16; 27.9 and 25.2 vs. 19.2 pg/ml, respectively). The increased levels of CXCL8 and CXCL16 were more pronounced in triple-negative and HER-2 positive patients, respectively. Binary logistic regression analysis revealed that CXCL8 was a significant predictor of BC, and such prediction was more depicted in triple-negative patients. The receiver operating characteristic analysis also revealed that CXCL8 recorded an area under curve of 0.998 in BC patients. In conclusion, CXCL8 is a potential biomarker for BC, especially when ER, PgR and HER-2 expression is considered. In this context, the predictive significance of CXCL8 in influencing BC progression is suggested in triple-negative patients.
It is an effect to draw attention to the aesthetic aspects and dedication And sounding the horizon of expectation among the public- the recipients- and knowing his taste
The Holy Qur’an is considered the miracle of God Almighty on earth, that will remain until the Hour of Resurrection, in which are evidences of His Power, Glory be to Him, and its verses are extremely perfect in miraculousness
الملخص شاع في الآونة الأخيرة استخدام طائرات الدرون في عمليات المسح والتوثيق الحقلي للمواقع الاثرية، حتى اصبح استخدام الدرون ضرورة أساسية تسبق أي عملية تنقيب اثري، من هذا المنطلق جاءت فكرة البحث لايضاح المبهم وإعطاء الأجوبة المناسبة لكثير من الأسئلة التي تطرح من قبل دارسي ومختصي الاثار، وسلط البحث الضوء على كل مايخص مفهوم الدرون وبدايات استخدامها في علم الاثار، واهم مكوناتها واجزائها الأساسية وخصائصها
... Show Moreالمستخلص ان هدف التنقيب عن الآثار هو في الأساس لحماية الآثار التي في باطن الارض وذلك لغرض دراستها والتعرف عليها للوصول الى الحقائق التي تخص مختلف العصور التي مرت على تلك المنطقة الأثرية ، وانطلاقا من هذا الهدف ستكون الطرق والوسائل العلمية المساعدة في عمليات التنقيب والحفر بأسلوب يضمن سلامة الأثر وحفظ المعلومات عنه وصيانته هي موضوع بحثنا هذا وسنحاول ان نركز على أهم الطرق العلمية الحديثة التي ظهرت في الف
... Show MoreMultiplicative inverse in GF (2 m ) is a complex step in some important application such as Elliptic Curve Cryptography (ECC) and other applications. It operates by multiplying and squaring operation depending on the number of bits (m) in the field GF (2 m ). In this paper, a fast method is suggested to find inversion in GF (2 m ) using FPGA by reducing the number of multiplication operations in the Fermat's Theorem and transferring the squaring into a fast method to find exponentiation to (2 k ). In the proposed algorithm, the multiplicative inverse in GF(2 m ) is achieved by number of multiplications depending on log 2 (m) and each exponentiation is operates in a single clock cycle by generating a reduction matrix for high power of two ex
... Show MoreWe studied the effect of certain environmental conditions for removing heavy metal elements from contaminated aqueous solutions (Cd, Cu, Pb, Fe, Zn, Ni, Cr) using the bacterium Bacillus subtilis to appoint the optimal conditions for removal ,The best optimum temperature range for two isolate was 30-35○C while the hydrogen number for the maximum mineral removal range was 6-7. The best primary mineral removal was 100 mg/L, while the maximum removal for all minerals was obtained after 6 hrs of Cu element time and the maximum removal efficiency was obtained after 24 hrs of Cu element. The results have proved that the best aeration for maximum removal was obtained at rotation speed of 150 rpm/minute. Inoculums of 5ml/100ml which contained 1
... Show MoreThe bank risks has greaten and changed in its nature under the developments of financial liberalization, banking innovation and increasing use for new financial instruments which created by the huge technological advancement happened in the banking industry. So that, banks in large choose to base the profitability measures adjusted for risks; that is we introduced this research. The most important reason led us to do this is the restriction to use the modern statistical methods by trade bank in Arab countries equally with world banks which were the antecedent to base those models. Therefore, the research problem is embedded in the banks need to use measures that link between profitability and risks and this is what achieved by RARC
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