The biomarker significance of three chemokines (CXCL8, CXCL10 and CXCL16) was evaluated in sera of 45 breast cancer (BC) and 28 benign breast lesion (BBL) patients, as well as 20 control women. Clinical stage and tumor expression of estrogen (ER), progesterone (PgR) and human epidermal growth factor receptor-2 (HER-2) receptors were considered in this evaluation. The results demonstrated that CXCL8, CXCL10 and CXCL16 showed a significant increased median in BC and BBL patients compared to control (CXCL8: 47.3 and 25.7 vs. 15.0; CXCL10: 37.6 and 30.7 vs. 13.1; CXCL16; 27.9 and 25.2 vs. 19.2 pg/ml, respectively). The increased levels of CXCL8 and CXCL16 were more pronounced in triple-negative and HER-2 positive patients, respectively. Binary logistic regression analysis revealed that CXCL8 was a significant predictor of BC, and such prediction was more depicted in triple-negative patients. The receiver operating characteristic analysis also revealed that CXCL8 recorded an area under curve of 0.998 in BC patients. In conclusion, CXCL8 is a potential biomarker for BC, especially when ER, PgR and HER-2 expression is considered. In this context, the predictive significance of CXCL8 in influencing BC progression is suggested in triple-negative patients.
العلاقات العراقية التركية في مجال المياه
يعدّ التطرف الفكري من أكبر الازمات التي تعرض لها العراق بصورة عامة ،
وبغداد بشكل خاص خلال حقب تاريخية مختلفة
Through tracingthe term “derivation” in the Holy Quran, I found that the word derivation varies and graduates in meaning from one form to another according to what has been mentioned in the Quranic context. In order to show that variation and graduation, we trace it in three axes:
The first axis (openness): the term “derivation” graduates from the meaning of openness and opening in its broad meaning to partial openness.
The second axis (the dispute): the term “derivation” participated with the general and private meaning, i.e. from hostility to antipathy.
Black slaves formed a section of the Murabit community, and they had an important role in wars and in settling battles to the Murabit state. Murabit state lords have depended on them in many scales such as, wars or within the community boarders
The aim of this research is to find out about the methods used by the teachers of the subjects (choir, voice training, singing groups) used to warm up in voice training. In the Department of Music of the Faculty of Fine Arts University of Baghdad. The limits of this research were for the academic year (2017-2018). Explanation in the theoretical framework of warm-up types The first part of the body warms the body in terms of relaxation, body moderation, head rotation, tongue exercises, mouth opening, facial mask movements, yawning.The second course will warm up the sound exercises warm up the sound through different ladders (diatonic and chromate), and ladder accordions.And the third topic warm up the impris
... Show Moreالشباب في مواجهة الارهاب (الدوافع والحلول)
In this research, trying to highlight the reasons for the illusion, and do not want to repeat what the previous scholars and researchers from the ancients and modernists said, but to continue from where they ended, as the blogging has undergone several images that influenced the nature of the narrations, and their proximity to the truth according to the whims of the authority, or the narrator's whims and inclinations and any destination. Here we don't mean bees and plagiarism... It goes beyond the fact that traffic is made to the whims of those who write or write to it, or in it a little bit of truth and then be framed, to add exaggeration and exaggeration to it.