The biomarker significance of three chemokines (CXCL8, CXCL10 and CXCL16) was evaluated in sera of 45 breast cancer (BC) and 28 benign breast lesion (BBL) patients, as well as 20 control women. Clinical stage and tumor expression of estrogen (ER), progesterone (PgR) and human epidermal growth factor receptor-2 (HER-2) receptors were considered in this evaluation. The results demonstrated that CXCL8, CXCL10 and CXCL16 showed a significant increased median in BC and BBL patients compared to control (CXCL8: 47.3 and 25.7 vs. 15.0; CXCL10: 37.6 and 30.7 vs. 13.1; CXCL16; 27.9 and 25.2 vs. 19.2 pg/ml, respectively). The increased levels of CXCL8 and CXCL16 were more pronounced in triple-negative and HER-2 positive patients, respectively. Binary logistic regression analysis revealed that CXCL8 was a significant predictor of BC, and such prediction was more depicted in triple-negative patients. The receiver operating characteristic analysis also revealed that CXCL8 recorded an area under curve of 0.998 in BC patients. In conclusion, CXCL8 is a potential biomarker for BC, especially when ER, PgR and HER-2 expression is considered. In this context, the predictive significance of CXCL8 in influencing BC progression is suggested in triple-negative patients.
كان من مظاهر تأثير اللغة العربية في الفارسية بعد الفتح الإسلامي، القرآن الكريم والحديث الشريف، فتأثر الشعراء والأدباء الإيرانيون بهما وبفنون أقوال العرب عموماً، فاقتبسوا في أشعارهم وكتاباتهم الفارسية أو العربية منها، كثيراً من الآيات والأحاديث والمصطلحات العربية، وهذا الاقتباس هو فنّ أدبي ينتمي الى المحسنات اللفظية والتي تشكّل مع المحسنات المعنوية عُنصُري علم البديع الذي هو فرع من ثلاثة علوم الى جانب عل
... Show Moreتُعَد السلطة السياسية في لبنان, هدفاً أساسياً لكل تنظيم سياسي, سواءأ كان حزب سياسي أم جماعة سياسية معينة. وبذلك ينشأ الصراع على السلطة, وهناك نوعان من الصراع السياسي يجري التمييز بينهما بدلالة فكرة الشرعية, فالتنافس يكون في النظام السياسي عندما ينعقد الاتفاق بين القوى الاجتماعية على اعتباره شرعي اً, ويكون الصراع على النظام السياسي عندما ينقطع الاتفاق بين هذه القوى على شرعيته, وان قوى المعارضة تعمل على الإطاحة
... Show Moreموازين النقد في الشعر الفارسي
Nesrin Erbil, Çağdaş Türk şiirinin kıvançla söyliyebileceğimiz öncü bir isimdir. Gerçek aşk, ayrılık, üzüntü, sevgiliye hasretin yetiştirdiği ve olanaksızlıklara haykıran bir sesidir. O bir Türkcesine tüm zencirleri kıran engelleri aşan sevgiyle sevgiye ve sevgiliye koşan kendi başına bir yaratıcılıktır. Şiirleri Erbil kokar yumuşak saçının tellerini Altın Köprü suyuyla yıkamayı diler. Yüreği ise Gürgür Baba’dır Türkmen için yanar.
Nesrin Erbil, 1960 yılından sonra Irak’ta gelişen yeni Türk edebiyatı ve serbest şiir akımının en önde gelen temsilcisi olarak, büyük ilgi toplamıştır. Şiire karşı olan merak
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لقد عرف سكان وادي الرافدين ، ومنذ أقدم العصور أهمية أشجار النخيل وما تقدمه من فوائد ضمن النواحي الاجتماعية والاقتصادية والدينية (1)، ولذلك أتسع نطاق زراعة النخيل من أرض سومر في الجنوب إلى شمال بابل ( باب ايلي )،وكانت اغلب البساتين مختصة بزراعة النخيل بالدرجة الأولى (2) ، وتعد تكريت( تكريتا) أو قلعة برتو (في العصر الآشوري) الحد الأعلى لهذا الامتداد ، ولكنها لا تنمو في بلاد أ
... Show MoreThe science of jurisprudence of the most honorable science, and engaged in the great reward with God Almighty; Today, they strive to highlight this tremendous wealth by searching for it, studying it, realizing it and presenting it to mankind for the purpose of benefiting from it.
It is a blessing to me that guided me to write in jurisprudence on the subject: (Delayed dowry in Islamic jurisprudence) Islamic law has preserved the rights of the wife to her husband, which is a financial and moral right. It is one of the provisions of the marriage contract and not a health condition and therefore marriage is held without mentioning in the contract.
The Baha'is are a group that belongs to the Baha'iya, the Baha'iya according to the encyclopedia of Religion Sciences is a modern religious sect appeared in existence in the middle of the ninetieth century. The number of their believers is around six million people of different parts of the world. its main center lies in Haifa city in Palestine.
إن موضوع العلاقات الحضارية بين المغرب و وادي الرافدين في عصر فجر التاريخ من المواضيع التي تعنى بإنتقال التأثيرات الحضارية العراقية إلى دول المغرب العربي عامة والمغرب خاصة . فقد إسترعى إنتباهي وجود إشارات مقتضبة أحيانا ومفصلة أحيانا أخرى عن تأثيرات في بعض الصناعات الفخارية والمعدنية والعمارة الدينية والدنيوية بين بلدان شرق البحر المتوسط والمغرب في
حقوق الانسان في الدستور الامريكي
Al-sarf science is one of the most scientifically accurate and rich in branches. Because it depends on the one accent and how the changes happened inside this science (from an event associated with time or not associated). The people who create this science and were deep made a tough rule to can out of these sentences without reason. The aim of this research is to declare (The Impossible Phenomenon in the Preference Name) and this study is separated into two chapters:
Section one: it’s content of (Preference) in the base books and the scientists of linguists and the rules that authorized building in the name of Preference.