Preferred Language
Articles
/
bijps-443
Polymeric Membrane Sensors for the Selective Determination of Metoclopramide Hydrochloride and their Applications to Pharmaceutical Analysis
...Show More Authors

Metoclopramide (MCP) ion selective electrodes based on metoclopramide-phosphotungstic acid (MCP-PT) ion pair complex in PVC matrix membrane were constructed. The plasticizers used were tri-butyl phosphate (TBP), di-octyl phenyl phosphonate (DOPP), di-butyl phthalate (DBPH), di-octyl phthalate (DOP), di-butyl phosphate (DBP), bis 2-ethyl hexyl phosphate (BEHP). The sensors based on TBP, DOPP, DBPH and DOP display a fast, stable and linear response with slopes 59.9, 57.7, 57.4, 55.3 mV/decade respectively at pH ranged 2-6. The linear concentration range between 1.0×10-5 – 1.0×10-2 M with detection limit 3.0×10-6 and 4.0×10-6 M for electrodes using TBP, DOPP and DBPH while electrode using DOP shows a linear concentration range between 3.0×10-5 – 1.0×10-2 M and detection limit 6×10-6 M. The selectivity coefficient values were calculated for MCP with respect to different inorganic cations, sugars and amino acids using the MCP depending on TBP plasticizer which is also used for the determination of MCP in pure solutions and in pharmaceutical preparations by direct, standard addition methods and as an indicator electrode in potentiometric titration with phosphotungstic acid (PT) giving satisfactory results.

Key words: Metoclopramide-HCl membrane sensors , Metoclopramide determination , pharmaceutical analysis , PVC membrane sensors  

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Synthesis of New Opioid Analgesic Peptide Analogues to Enkephalin (Leucine- and Methionine-Enkephalin)
...Show More Authors

A small number of researches were done in the design and synthesis of enkephalin analogues that are able to resist degradation effect of proteolytic enzymes with good bioavailability and half-lives.Through studying structure activity relationships we tried to incorporate phthalyl group, tryptophan and lysine amino acids in different positions in the basic backbone structure of the naturally occurring opioid Leu5- and Met5- enkephalin, in the hope that such insertion of these amino acids could induce interesting addition in the biological activity of these analogues with enhancement of their bioavailability, in addition to decrease side effects as addiction liability.

These synthesized peptides are:

    ... Show More
    View Publication Preview PDF
    Crossref
    Publication Date
    Fri Sep 01 2023
    Journal Name
    Cellular, Molecular And Biomedical Reports
    Investigation of GJB2 and SLC26A4 genes related to pendred syndrome genetic deafness patients
    ...Show More Authors

    View Publication
    Crossref (1)
    Crossref
    Publication Date
    Tue Jan 31 2017
    Journal Name
    Journal Of Engineering
    Behavior of Reinforced Concrete Columns Subjected to Axial Load and Cyclic Lateral Load
    ...Show More Authors

    Columns subjected to pure axial load rarely exist in practice. Reinforced concrete columns are usually subjected to combination of axial and lateral actions and  deformations, caused by  spatially‐complex loading patterns as during earthquakes causes lateral deflection that in turn affects the horizontal stiffness. In this study, a numerical model was developed in threedimensional nonlinear finite element and then validated against experimental results reported in the literatures,
    to investigate the behavior of conventionally RC columns subjected to axial load and  . lateral reversal cyclic loading. To achieve this goal, numerical analysis was conducted by using finite element program ABAQUS/Explicit. The variables co

    ... Show More
    View Publication Preview PDF
    Publication Date
    Sun Jun 02 2019
    Journal Name
    Journal Of The College Of Languages (jcl)
    Analysis of Verbs Forms in Sa’eed Faeeq’s Short Story: Cloud in the Sky: Sait Faik'in "Havada Bulut" Adlı Hikayesinde Fiil Kiplerinin İncelenmesi.
    ...Show More Authors

    This research paper which is entitled “Analysis of Verbs Forms in Sa’eed Faeeq’s Short Story: Cloud in the Sky” deals with the forms of verbs (i.e., kinds of tenses and suffix analysis). It is one of the applied studies. Verbs are basic elements in Turkish sentences. Their function is to state the predicate which is a sentential essential part. Verbs denote sentence construction, action and formal aspects. Forms are added to the base of verbs in the Turkish language giving the verbs their final structures. Such structures are set in a distinct planned way. The verbs used in the Turkish language which are distinguished by one of these forms are known as simple tense verbs.

    Sait Faik'in ( "Havada Bulut" adlı Hikayesinde Fi

    ... Show More
    View Publication Preview PDF
    Crossref
    Publication Date
    Mon May 01 2023
    Journal Name
    3 Biotech
    Detection of orthodontically induced inflammatory root resorption-associated biomarkers from the gingival crevicular fluid by proteomics analysis: a randomized-controlled clinical trial
    ...Show More Authors

    View Publication
    Crossref (3)
    Crossref
    Publication Date
    Sun Apr 03 2016
    Journal Name
    Journal Of Educational And Psychological Researches
    ( the effect of Cognitive Acceleration strategy and random excitement strategy in achievement of geography material and developing the reflective thinking for students of literary fifth class)
    ...Show More Authors

    The research aims to find out the effect of Cognitive Acceleration strategy and random excitement strategy in achievement of geography material and developing the reflective thinking for students of literary fifth class . 

      the researcher depended a partial control experimental design with the three groups(the competence groups of the pre & post tests), The sample is deliberately selected  from first AL-Rusafah Directorate General of Education in Baghdad.  AL.fardoos Interme

    ... Show More
    View Publication Preview PDF
    Publication Date
    Thu Mar 01 2018
    Journal Name
    Journal Of Engineering And Sustainable Development
    MEASURING THE URBAN INTEGRAL SUSTAINABILITY IN “MUSTANSIRIYA UNIVERSITY “ACCORDING TO THE INTEGRAL DESIGN THEORY
    ...Show More Authors

    View Publication
    Crossref
    Publication Date
    Sun Dec 01 2013
    Journal Name
    Journal Of Economics And Administrative Sciences
    Using Time Series Methods To Modify The Seasonal Variations in the Consumer Price Index
    ...Show More Authors

         As is  known that the consumer price index (CPI) is one of the most important  price indices because of its direct effect on the welfare of the individual and his living.

           We have been address the problem of Strongly  seasonal  commodities in calculating  (CPI) and identifying some of the solution.

       We have  used an actual data  for a set of commodities (including strongly seasonal commodities) to calculate the index price by using (Annual Basket With Carry Forward Prices method) . Although this method can be successfully used in the context of seasonal&nbs

    ... Show More
    View Publication Preview PDF
    Crossref
    Publication Date
    Mon Jun 01 2015
    Journal Name
    Journal Of Economics And Administrative Sciences
    Using the Logistic Regression Model in Studding the Assistant Factors to Diagnose Bladder Cancer
    ...Show More Authors

    The cancer is one of the biggest health problems that facing the world . And  the bladder cancer has a special place among the most spread cancers in Arab countries specially in Iraq and Egypt(2) . It is one of the diseases which can be treated and cured if it is diagnosed early . This research is aimed at studying the assistant factors that diagnose bladder cancer such as (patient's age , gender , and other major complains of hematuria , burning or pain during urination and micturition disorders) and then determine which factors are the most effective in the possibility of diagnosing this disease by using the statistical model (logistic regression model) and depending on a random sample of (128) patients . After

    ... Show More
    View Publication Preview PDF
    Crossref
    Publication Date
    Wed Mar 10 2021
    Journal Name
    Baghdad Science Journal
    Analysis of curved optical absolute visual fates of super colony of Type II (SN II)
    ...Show More Authors

    Were analyzed curved optical fates Almarchih absolute colony of the binary type, the Great Palmstqrh using mathematical relationships derived for that and that gave us the results closer to the results of the observed spectral Great Colonial

    View Publication Preview PDF