Background: Tumor necrosis factor-alpha (TNF-α) and interleukins play important roles in the pathogenesis of rheumatoid arthritis (RA). Genetic research has been employed to find many of the missing connections between genetic risk variations and causal genetic components. Objective: The goal of this study is to look at the genetic variations of TNF-α and interleukins in Iraqi RA patients and see how they relate to disease severity or response to biological therapy. Method: Using specific keywords, the authors conducted a systematic and comprehensive search to identify relevant Iraqi studies examining the genetic variations of TNF-α and interleukins in Iraqi RA patients and how they relate to disease severity or response to biological therapy. Results: Thirteen studies have looked at TNF-α and interleukin genetic polymorphisms in Iraqi RA patients. Only the IL-2, IL-4, IL-6, IL-17, and IL-23 receptor gene polymorphisms were explored for interleukins; however, the results of studies indicate no association between genetic polymorphism and the severity of RA. Very few researchers examine the correlation between genetic variation and TNF-α inhibitor responsiveness. Numerous studies have been conducted to investigate the genetic variations of the TNF-α promoter. The -308 G/A region in the promotor region was the most studied location.
Abstract
Objective(s): To assess the job satisfaction during of covid-19 among the nurses in respiratory isolation units of coronavirus disease.
Methodology: A descriptive cross-sectional design was carried out in four hospitals at isolation units of coronavirus disease from the period (21th December, 2021 to 27th January, 2022). A non-probability (convenience) sampling method consists of (300) nurse was selected convenience based on the study criteria. The tool used to measure the job satisfaction is Job satisfaction scale for clinical nursing (JSS-CN). This tool consists of two parts, the first part is for demographic information and consists of 8 items, and the second
... Show MoreIrisin is a myokine that controls energy metabolism by making adipose tissue brown. The present goal in doing this research was to determine how irisin concentration relates to other biochemical markers of disease. Hemodialysis (HD) for chronic kidney failure. The study included 30 individuals with end-stage renal disease on HD and 30 healthy subjects as the control group. The ages of all patients and the control group ranged from (25 to 60) years. The excluded criteria included patients with viral hepatitis and diabetes. Serum irisin concentration and the level of fasting serum glucose (FSG), urea, creatinine (Cr), total protein (TP), albumin (Alb), albumin to creatinine ratio (ACR), total cholesterol (TC), alanine aminotransferase (ALT),
... Show MoreTranslating poetry is considered one of the most complicated types of translations. It
encounters many difficulties, the most important of which is the question of possibility or
impossibility of translating poetry. So, it is better to start by asking the following question: is
the translation of poetry possible? Or is it impossible? It is definitely a rhetorical question
because translation is as old as the presence of translated texts, which fills the shelves of
libraries. One can ask despite these difficulties, who would discourage people of the world
from translating poetry merely because it is fundamentally impossible? (Mann, 1970: 211)
The present paper will elaborate, in more detail, upon the necessary traits
Abstract In this paper, the researcher accounts for two different points of view concerning the tense of infinitive clauses in English language when functioning as verb complementation, and explains their bases and justifications. Some grammarians postulate that infinitive clauses complementation are tensed clauses, having the feature tense , since they, sometimes, indicate time relations different from that of the matrix clause, while most grammarians and linguists say that infinitive clauses, in their two types- 'to'- infinitives and bare infinitives, are tenseless clauses; they are nonfinite clauses. Grammarians state that infinitive clauses functioning as verb complementation are tensed clauses due to the presence of some temp
... Show MoreBackground:Hydrocephalus is dilatation of the ventricular system due to excessive production and/ or obstruction of cerebrospinal fluid (CSF) pathways. Different surgical procedure are used to treat this disease. Ventriculo peritoneal shunt is by far the most popular technique for CSF diversion..
Objective;To compare the programmable and non-programmable valves regarding the complications of both types
Methods:This study was conducted in the Neurosurgical hospital of Baghdad/Iraq over a period of 3 years from July 2008 to August 2011.
A special inclusion criteria has been tabulated for the selection of patients..
Results:.Fifty cases with hydrocephalus admitted and diagnosed by CT scan and treated by ventriculoperitoneal shun
Gender and culture are among the factors that influence the process of understanding and interpreting different types of communication, especially images. The current study, which is a part of a master’s thesis, aims at investigating the role of gender and culture in interpreting and understanding the caricatures that deal with women’s issues in Arab societies. To this end, the researchers adopted Barthes’ (1957) concepts of denotation and connotation in his theory of mythologies in addition to Langacker’s (1987) theory of (Domains). The research concludes that the female subjects have better cognitive abilities in investing the signs within the selected caricatures. The other factor the study reached to is that the respondents
... Show MoreThe fingerprinting DNA method which depends on the unique pattern in this study was employed to detect the hydatid cyst of Echinococcus granulosus and to determine the genetic variation among their strains in different intermediate hosts (cows and sheep). The unique pattern represents the number of amplified bands and their molecular weights with specialized sequences to one sample which different from the other samples. Five hydatitd cysts samples from cows and sheep were collected, genetic analysis for isolated DNA was done using PCR technique and Random Amplified Polymorphic DNA reaction(RAPD) depending on (4) random primers, and the results showed:
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Abstract
Leadership has now become a process for applying methods and techniques that make the Organization at the top of its competitive pyramid a greater market share. Leadership has become a focus for all leaders and managers، and leaders and managers are increasingly seeking to develop their skills and leadership skills. The research started with a clear problem of specific questions to ensure that the general objective of the research is to describe the characteristics of the leader and to clarify the dimensions of empowering the workers and to highlight the role of the leader in empowering the workers. The study examines the relation between the role of the leader in
... Show MoreObesity is an escalating health problem in developing countries. One to ten children worldwide are overweight in a report showed by the International Obesity Task Force. Ghrelin, orexigenic peptide, has 28 amino acids, it is considered the greatest remarkable promotion in the last two decades for understanding the physiological changes of action regulating food intake and hunger. Obestatin is a 23-amino acid peptide nearly connected to ghrelin that secures from substitutio
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