One of the most important parameters determining structural members' durability and strength is the fire flame's influence and hazard. Some engineers have advocated using advanced analytical models to predict fire spread impact within a compartment and considering finite element models of structural components to estimate the temperatures within a component using heat transfer analysis. This paper presented a numerical simulation for a reinforced concrete beam’s structural response in a case containing Water Absorbing Polymer Spheres (WAPS) subjected to fire flame effect. The commercial finite element package ABAQUS was considered. The relevant geometrical and material parameters of the reinforced concrete beam model at elevated temperature are first suggested as a numerical model. After that, the suggested numerical model was validated against the experimental tests conducted in this study. The validated numerical model was used to conduct a parametric study to investigate the effects of two important parameters on the structural behavior after being exposed to fire flame. The effect of burning temperatures (500, 600, and 700) oC, as well as the influence of fire duration (1 and 2) hours, were included. The experimental program validation requirement comprised four self-compacted reinforced concrete beams each of the same geometric layout (150x200x1500) mm, reinforcing details, and compressive strength (fc'=50 MPa). Four percentages of (WAPS) were considered (0, 1, 2, and 3)%. The specimens were exposed to a fire flame with a steady-state temperature (500°C), a rising rate compatible with ASTM-E119, a one-hour duration, and a sudden cooling procedure. A static (two-point) load was applied to the burned beams. Through the assessed numerical model, the numerical analysis offered by the WAPS ratio effect was carried out for the reinforced concrete beam under the effect of static load. The findings revealed that the WAPS ratio substantially impacted structural behavior. The numerical model's results were in reasonable agreement with the experimental results. Concerning the fire exposure duration (two hours) at 500 oC, the specimens containing a ratio (3%) of WAPS improved the ultimate load and the ultimate deflection by about (46.63 and 72.24)%, respectively. The highest percentage variation of the absorbed energy at failure load was also detected in the ratio (3%) to be (139.43) %. As for the hardening concrete properties (compressive strength, splitting tensile strength, and modulus of elasticity), the residual strength was (61.06, 48.87, and 32.00)%, respectively. Regarding the steady-state burning temperature (500, 600, and 700)oC for a one-hour duration, the specimens with a ratio of (3%) WAPS improved the ultimate load by about (40.70, 62.00, and 40.76)%, respectively, corresponding to zero percentage of WAPS. The residual compressive strength, splitting tensile strength, and modulus of elasticity were (72.40, 56.12, and 43.78)%, (74.36, 56.50, and 44.79)%, and (45.23, 36.57, and 28.94)%, respectively.
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Background: Dolutegravir sodium (DTG), used to treat HIV, faces challenges in delivering effective therapeutic concentrations to the brain due to the blood-brain barrier (BBB). Nanostructured lipid carriers (NLCs) combined with in situ gels present a promising strategy for enhancing brain drug delivery via the intranasal route. Objective: To compare brain pharmacokinetics of DTGs delivered via NLC-loaded in situ gel intranasal administration with the conventional intravenous (IV) drug solution. Methods: 80 Wistar rats, which were divided into three groups: two groups consisting of 39 animals each and a control group with 2 animals. Rats were administered with a dose of 1.0 mg/kg of DTGs IV, and DTGs NLC-loaded in situ gel were admin
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In this study, NAC-capped CdTe/CdS/ZnS core/double shell QDs were synthesized in an aqueous medium to investigate their utility in distinguishing normal DNA from mutated DNA extracted from biological samples. Following the interaction between the synthesized QDs with DNA extracted from leukemia cases (represents damaged DNA) and that of healthy donors (represents undamaged DNA), differential fluorescent emission maxima and intensities were observed. It was found that damaged DNA from leukemic cells DNA-QDs conjugates at 585 nm while intact DNA (from healthy subjects) DNA–QDs conjugates at 574 nm. The obtained results from the optical analyses indicate that the prepared QDs could be utilized as probe for detecting disrupted DNA th
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The permeability estimates for the uncored wells and a porosity function adopting a modified flow zone index-permeability crossplot are given in this work. The issues with implementing that approach were mostly crossplots, due to the influence of geological heterogeneity, did not show a clear connection (scatter data). Carbonate reservoir flow units may now be identified and characterized using a new approach, which has been formally confirmed. Due to the comparable distribution and flow of clastic and carbonate rock fluids, this zoning method is most effective for reservoirs with significant primary and secondary porosity. The equations and correlations here are more generalizable since they connect these variables by combining cor
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This study analyses six political cartoons selected based on their relevance to current Iraqi political issues, specifically the period between 2005 and 2015, from American online newspapers (calgecartooms.com). The selection criteria included the cartoons' satirical elements, visual rhetoric, and their ability to engage with themes such as power dynamics, social issues, and public opinion. It sheds light on how these cartoons can function as mediators of meanings between the cartoonists and the readers. The data is examined using multimodal discourse analysis (MDA), which combines language study with the analysis of other visual elements, like colors, gestures, and images, to understand meaning (O’Halloran et al., 2011). The Visual Socia
... Show MoreNatural convection in a trapezoidal enclosure with partial heating from below and symmetrical cooling from the sides has been investigated numerically. The heating is simulated by a centrally located heat source on the bottom wall, and four different values of the dimensionless heat source length, 1/5, 2/5, 3/5, 4/5 are considered. The laminar flow field is analyzed numerically by solving the steady, two-dimensional incompressible Navier-Stokes and energy equations. The Cartesian velocity components and pressure on a collocated (non-staggered) grid are used as dependent variables in the momentum equations discretized by finite volume method; body fitted coordinates are used to represent the trapezoidal enclosure, and grid generatio
... Show MoreIn this study, from a total of 856 mastitis cases in lactating ewes, only 34 Streptococcus agalactiae isolates showed various types of resistance to three types of antibiotics (Penicillin, Erythromycin and Tetracycline). St. agalactiae isolates were identified according to the standard methods, including a new suggested technique called specific Chromogenic agar. It was found that antibiotic bacterial resistance was clearly identified by using MIC-microplate assay (dilution method). Also, by real-time PCR technique, it was determined that there were three antibiotics genes resistance ( pbp2b, tetO and mefA ). The high percentage of isolate carried of a single gene which was the Tetracycline (20.59%) followed by percentage Penicillin was
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