Anticancer Activity of New Di-Nuclear Copper (I) Complex

Taghreed Al-Noor

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Publication Date

Thu Jan 01 2015

Journal Name

Chemistry And Materials Research

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Anticancer Activity of New Di-Nuclear Copper (I) Complex

Taghreed Al-Noor

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In-vitro biological activities of the free new H4L ( indole-7-thiocarbohydrazone) ligand and its Ni(II), Pd(II) , Pt(II), Cu(II), Ag(I), Zn(II) and Cd(II) complexes are screened against two cancerous cell lines, that revealed significant activity only for [Cu2Cl2(H4L)2(PPh3)2] after 72 h treatment by the highest tested concentrations. The Copper(I) complex was characterized by X-ray Crystallography and the NMR spectra, whereas it has been confirmed to have momentous cytotoxicity against ovarian, breast cancerous cell lines (Caov-3, MCF-7). The apoptosis-inducing properties of the Cu(I) complex have been investigated through fluorescence microscopy visualization, DNA fragmentation analysis and propidium iodide flow cytometry.

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Publication Date

Mon Jan 01 2018

Journal Name

World Journal Of Dentistry

Differential Expression of Toll-like Receptor 4 and Nuclear Factor κB of Primary Rat Oral Keratinocytes in Response to Stimulation withFusobacterium nucleatum

Ali A

Hayder R

Ahmed K

Saif S

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(2)

Publication Date

Wed Apr 01 2020

Journal Name

International Journal Of Pharmaceutical Research

Synthesis, Characterization, Study the Toxicity and Anticancer Activity of N,O-Chitosan Derivatives

Azetidinone

Thiazolidinone

Tetrazole

Oxazepine

Chitosan derivatives

Anticancer activity

Toxicity study.

R.S.

M S

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(12)

(1)

Publication Date

Sun Nov 01 2020

Journal Name

Journal Of Physics: Conference Series

Synthesis, Characterization, Antibacterial study and Efficiency of Inhibition of New di-β-enaminone Ligand and its Complexes

Awf A. R.

Enass J.

Ahmed T.

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AbstractThe new ligand [3,3’-(1,2-phenylenebis(azanediyl))bis(5,5-dimethylcyclohex-2-en-1-one)] (L) derived from 5,5-Dimethylcyclohexane-1,3-dione with 1,2-phenylenediamine was used to prepare a new chain of metal complexes of Mn(ii), Co(ii), Ni(ii), Cu(ii), Cd(ii) and Zn(ii) by inclusive formula [M(L)]Cl2. Characterized compounds on the basis of 1H, 13CNMR (for ligand (L)), FT-IR and U.V spectrum, melting point, molar conduct, %C, %H and %N, the percentage of the metal in complexes %M, Magnetic susceptibility, thermal studies (TGA), while its corrosion inhibition for (plain steel) in tap water is studied by weight loss. These measurements proved th ... Show More

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(8)

Publication Date

Mon Jan 15 2024

Journal Name

Mammalia

Brandt’s Hedgehog, Paraechinus hypomelas (Brandt, 1836), new to the mammal fauna of Iraq

biogeography

erinaceomorpha

insectivores

range expansion

wild mammals of Iraq

Omar F.

Soran H.

Soma I.

Boris

Gholam H.

Korsh

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AbstractDue to the wide distribution through the Iranian Plateau, especially in its western parts adjacent to Iraq’s northeastern borders, the occurrence of Brandt’s Hedgehog <italic>Paraechinus hypomelas</italic> (Brandt, 1836) was suspected, but no confirmed records were made. In 2021–2023, several sightings were obtained during <italic>in situ</italic> surveys in the Bamo-Khoshk Mountains in the Kurdistan region-northeastern Iraq which confirm the first occurrence of this species in the country.

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(1)

Publication Date

Wed Jan 01 2025

Journal Name

Rsc Advances

Development of a multi-source blue light irradiation platform for photometric quantification of ascorbic acid via continuous absorbance quenching of the ferric–thiocyanate complex

Ghufran k.

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Diagram of CFIA system: (A) Fe ³⁺ line; (B) SCN ⁻ line; (C) A.A carrier; (D) sample valve; (E) mixing/reaction coil quenched by A.A; (F) blue LED detector.

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(2)

(4)

Publication Date

Tue Jun 20 2023

Journal Name

Baghdad Science Journal

Visible-Light-driven Photocatalytic Properties of Copper(I) Oxide (Cu2O) and Its Graphene-based Nanocomposites

Cu2O

Graphene-based nanocomposites

Nanocrystals

Photocatalytic evaluation

Visible-Light

Abdul Waheed

Gul

Elyor

Basant

Aigul Baimagambetova

Ahmad Hosseini

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In this study, an improved process was proposed for the synthesis of structure-controlled Cu2O nanoparticles, using a simplified wet chemical method at room temperature. A chemical solution route was established to synthesize Cu2O crystals with various sizes and morphologies. The structure, morphology, and optical properties of Cu2O nanoparticles were analyzed by X-ray diffraction, SEM (scanning electron microscope), and UV-Vis spectroscopy. By adjusting the aqueous mixture solutions of NaOH and NH2OH•HCl, the synthesis of Cu2O crystals with different morphology and size could be realized. Strangely, it was found that the change in the ratio of de-ionized water and NaOH aqueous solution led to the synthesis of Cu2O crystals of differen

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Publication Date

Wed Jan 01 2020

Journal Name

Research Journal Of Pharmacy And Technology

Insilico and in vitro Approach for Design, Synthesis, and Anti-proliferative Activity of Novel Derivatives of 5-(4-Aminophenyl)-4-Substituted Phenyl-2, 4-Dihydro-3H-1, 2, 4-Triazole-3-Thione

Ammar A. Razzak Mahmood

Wurood A.

Nada N

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(9)

(8)

Publication Date

Fri Jul 28 2023

Journal Name

The Journal Of Physical Chemistry A

Tubular Magnetic Shielding Scan (TMSS): A New Technique for Molecular Space Exploration. (i) The Case of Aromaticity of Benzene and [n]Paracyclophanes

tubular magnetic shielding scan (TMSS)

nonplanar aromatic molecules

aromaticity

nucleus-independent chemical shift (NICS)

magnetic shielding

Muntadar A. H.

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Both traditional and novel techniques were employed in this work for magnetic shielding evaluation to shed new light on the magnetic and aromaticity properties of benzene and 12 [n]paracyclophanes with n = 3–14. Density functional theory (DFT) with the B3LYP functional and all-electron Jorge-ATZP and x2c-TZVPPall-s basis sets was utilized for geometry optimization and magnetic shielding calculations, respectively. Additionally, the 6-311+G(d,p) basis set was incorporated for the purpose of comparing the magnetic shielding results. In addition to traditional evaluations such as NICS/NICSzz-Scan, and 2D-3D σiso(r)/σzz(r) maps, two new techniques were implemented: bendable grids (BGs) and cylindrical grids (CGs) of ghost atoms (Bqs). BGs a

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(5)

Publication Date

Thu Aug 18 2022

Journal Name

Journal Of Interdisciplinary Mathematics

New subclasses for estimates coefficients of m-fold symmetric bi-univalent functions and Fekete-Szego problems

Ali Musaddak

Kassim A.

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(2)

Publication Date

Tue May 06 2014

Journal Name

Plos One

Gastroprotective Activity of Ethyl-4-[(3,5-di-tert-butyl-2-hydroxybenzylidene) Amino]benzoate against Ethanol-Induced Gastric Mucosal Ulcer in Rats

Mohammed Farouq

Raied Mustafa

Daleya Abdulaziz

Nahla Saeed

Abdulwali

Pouya

Maryam

Anwar

Mahmood Ameen

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The study was carried out to determine the cytotoxic, antioxidant and gastro-protective effect of ethyl-4-[(3,5-di-tert-butyl-2-hydroxybenzylid ene)amino] benzoate (ETHAB) in rats.

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