Cryptography is the technology of protecting information and communication by means of encoding the sending information. Existing methods often operate within predetermined mathematical structures which can be subject to pattern recognition and which are lack biological randomness. To address these challenges, this paper introduced a new bio-inspired cryptography approach to protect text messages using the coding mechanisms of DNA and RNA materials. The encryption system consists of six steps: encoding the plaintext message into DNA sequences, transcribing DNA into RNA, applying the complementary base pairing, scrambling RNA segments, optional reverse transcription, and encoding the resulting DNA-RNA characters into ciphertext. Randomization is used in the encoding of DNA and in the scrambling of RNA to make each encryption instance different from the other. This method was tested with varying sizes of messages, and it has proved very efficient in terms of time between encryption and decryption. This approach has created new opportunities for the creation of new classes of secure cryptographic systems bio-inspired to get modern methods of digital communication.
