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THE FORMS AND FUNCTIONS OF APOLOGIES WITH INDICATIVE REFERENCES TO THE LETTERS OF KEATS AND BYRON
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11-22 Description An apology may be defined as “the act of declaring one’s regret, remorse or sorrow for having insulted, failed, injured, harmed or wronged another (Internet Encyclopedia of Philosophy IEP). A definition quite interested in the function suggests that “an apology is a speech act addressed to B’s face–needs and intended to remedy an offence for which A. takes responsibility.”(Holmes, 1990: 159). Apologies are also" speech acts" that are hard to identify, define or categorize, a difficulty that arises directly out of the functions they perform (Lakoff, 2001: 201) and the forms they take. In function, they range from selfabasement for wrongdoing to the formal display of appropriate feeling. In form, they range from explicit apologies to the most ambiguous ones. Apologies matter theoretically because they are rich in forms and functions. They also involve intricate presuppositions and / or assertions. Their attracti on is that they either blur things or explicitly stae them. Moreover, their theoretical richness as unique human activities shows in the categories they take i.e. register, genre and key etc. Practically, apologies matter because, as speech acts, they are felicitous from the speaker's perspective and soothing for the addressee. Apologies are needed on both individual and social levels. On an individual level, they appease the listener. On a social level, they smooth things and bring harmony to the parties involved. Talking about apologies ushers us to an operative linguistic discipline nowadays, namely Pragmatics. Stalnker’s definition of this discipline is quite helpful: Pragmatics is the study of the purpose for which sentences are used, of the real world conditions under which a sentence may be appropriately used as an utterance (1972:380). In a relevant sense, apologies are thematically enticing and practically significant as pragmatic ‘speech acts’, they postulate a daunting task by virtue of their f luidity and of the intricate relations between their forms and functions, and, in a deeper linguistic sense, the relations between language and its context of utterance.

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Publication Date
Wed Nov 19 2014
Journal Name
Journal Of Biosciences
Caspase-like proteins: Acanthamoeba castellanii metacaspase and Dictyostelium discoideum paracaspase, what are their functions?
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Cholinesterases are among the most efficient enzymes known. They are divided into two groups: acetylcholinesterase (AChE) involved in the hydrolysis of the neurotransimitter acetylcholine, and butyrylcholinesterase (BChE) of unknown function. Several crystal structures of the former have shown that the active site is located at the bottom of a deep and narrow gorge. Human BChE has attracted attention because it can hydrolyze toxic esters and nerve agents. Here we analyze the complexes of cholinesterase with soman by describing the 3D geometry of the complex, the active site, the changes happened through the inhibition and provide a description for the mechanism of inhibition. Soman undergoes degradation in the active site of the AChE and B

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Publication Date
Sun Mar 09 2008
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Studying of the complexes product of the nerve agent Soman with the Butyrylcholinesterase and Acetylcholinesterase Enzymes
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Cholinesterases are among the most efficient enzymes known. They are divided into two groups: acetylcholinesterase (AChE) involved in the hydrolysis of the neurotransimitter acetylcholine, and butyrylcholinesterase (BChE) of unknown function. Several crystal structures of the former have shown that the active site is located at the bottom of a deep and narrow gorge. Human BChE has attracted attention because it can hydrolyze toxic esters and nerve agents. Here we analyze the complexes of cholinesterase with soman by describing the 3D geometry of the complex, the active site, the changes happened through the inhibition and provide a description for the mechanism of inhibition. Soman undergoes degradation in the active site of the AChE and BC

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