Rutting is a crucial concern impacting asphalt concrete pavements’ stability and long-term performance, negatively affecting vehicle drivers’ comfort and safety. This research aims to evaluate the permanent deformation of pavement under different traffic and environmental conditions using an Artificial Neural Network (ANN) prediction model. The model was built based on the outcomes of an experimental uniaxial repeated loading test of 306 cylindrical specimens. Twelve independent variables representing the materials’ properties, mix design parameters, loading settings, and environmental conditions were implemented in the model, resulting in a total of 3214 data points. The network accomplished high prediction accuracy with an R2 of 0.93 and a mean squared error (MSE) of 0.0039. Results based on the sensitivity analysis and variable importance techniques showed that the percentage of aggregate passing the 4.75 mm sieve and the (rice) theoretical maximum specific gravity (Gmm) were the most significant factors in predicting axial permanent strain (εp). Furthermore, the connection weight method highlighted input variables’ distinct positive and negative impacts on permanent deformation.
