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Irisin, a promising adipomyokine, shows low levels in relation to periodontal diseases, unlike visfatin and IL-6 (case-control study)
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Introduction

Adipose tissue releases pro- and anti-inflammatory cytokines and hormones such as irisin, visfatin, and interleukin-6, which may be linked to periodontal diseases.

Objectives

Our study aimed to determine salivary irisin, visfatin, and interleukin-6 levels in gingivitis and periodontitis patients, compare them with healthy periodontal patients, and evaluate the association between these biomarkers.

Materials and methods

Ninety participants were involved in this case-control study: 30 patients diagnosed with periodontitis (P), 30 patients with gingivitis (G), and 30 periodontally healthy subjects (control; C). The periodontal clinical parameters were documented. The ELISA test examined irisin, visfatin, and interleukin-6 saliva levels. Data were analyzed using SPSS (V.29).

Results

Irisin significantly decreased in gingivitis and periodontitis compared to the control group ( p  < 0.05). In contrast, gingivitis and periodontitis reported elevated levels of visfatin and interleukin-6 compared to the control group ( p  < 0.05). Visfatin levels did not significantly change between gingivitis and periodontitis ( p  > 0.05). All periodontal clinical measures showed a significant negative association with irisin ( p  < 0.05), except plaque index in the gingivitis group. At the same time, visfatin and interleukin-6 showed significant positive relationships with all clinical periodontal markers ( p  < 0.05).

Conclusions

Salivary irisin levels were reduced in individuals with gingivitis and periodontitis, whereas visfatin and interleukin-6 levels were elevated. These biomarkers may predict susceptibility to periodontal disease.

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Publication Date
Fri Mar 02 2018
Journal Name
Journal Of Language Studies
Activating Functional Formulas of EFL Learners` Fluency and Accuracy Skills at the College of Education for Human Sciences (Ibn Rushd)
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Job pressures affecting the quality of teachers’ performance at the College of Physical Education and Sports Sciences/University of Baghdad
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Publication Date
Sat Dec 01 2018
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Causal relationship between sugar prices, imported sun flower oil, crude oil prices and the exchange rate of the Iraqi dinar
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Abstract

The increasing of some traded Agricultural crops prices coincide with the increasing of crude oil prices in global market since the beginning of 21st century which indicate the possibility of short run and long run causality relation between the imported economic variables. The study aims to analysis the causality effects between some of Agricultural crops prices imported by Iraq and the prices of crude oil and Iraq dinar exchange rate   in global markets for period (2004:1 -2016:4) theory for developing the adequate price and economic police for Iraqi economic sector. The results show the existence of short- run and long- run between the eco

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