The goal of this study was to investigate the protein peroxidation role by measuring serum levels of advanced oxidation protein products (AOPP) in type 2 diabetic patients with or without retinopathy and comparing them to controls to see if circulating AOPP levels can be used as a detection biomarker for DR. And see which of the two widely used antidiabetic treatment groups had the most impact on this oxidative stress marker. The groups were divided into two subgroups: 1) 70 type 2 diabetic patients (36 male, 34 female), 35 with diabetic retinopathy (DR) and 35 with no evidence of DR, and 2) non-diabetic controls (11 male, 9 female) were chosen from Ibn AL-Haitham Hospital for Ophthalmology and a Specialized Center for Endocrinology and Diabetes. AOPP levels were significantly higher in diabetic patients with (12.5±5.6 ng/ml) or without DR (5.1±4 ng/ml) when compared to those of controls (1.45 0.8 ng/ml) (p<0.05). AOPP levels were higher in the late stage of DR compared to the early stage(14 3.15 ng/ml ) and ( 10 2.13 ng/ml) respectively so. Furthermore, Dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitors) cause a better reduction in AOPP levels compared to Sulfonylureas (SUs) in the NDR group. Increased protein oxidation may involve in the pathogenesis and severity of DR and the serum AOPP levels have the prospect to become a marker for the diagnosis of DR. DPP-4 inhibitors were better in slowing the progression of the disease compared to SUs.
تضمن هذا البحث علاقة التفسير الفقهي بالتفسير بالمأثور، وتبين أنها علاقة تلازم وترابط؛ لأنَّ الفقه هو استنباط الأحكام من أدلة الكتاب والسُّنة، وقد اعتنى بذلك المفسرون وشُرّاح الحديث، وكل واحدة منهما لا تتميز عن غيرها في الحاجة، ولا تستغني عنها في درك ما تنحوه من البغية والإرادة؛ ذاك لأنَّ الحديث بمنزلة الأساس الذي يعد الأصل، والفقه بمنزلة البناء الذي هو له كالفرع، وكل بناء لم يوضع على قاعدة وأساس فهو منهار،
... Show Moreأساس انتقال المخاطر في عقود التجارة الدولية
الآت الاطفال الموسيقية الشعبية والتقليدية في التربية
تبلور مفهوم مركزية الانسان بالنسبة للإنسان والاعلاء من شأنه و عده قيمه أعلى من الوجود ، هذا الادراك الوجودي هو ما يسمى بالنزعة الانسانية، وتعد النزعة الانسانية هنا احد أهم التيارات التي ظهرت في الفكر السياسي الغربي الحديث، إذ تعد هذه النزعة من أهم الحركات الفكرية والتربوية التي توجت عصر النهضة الاوربي وفجرت ينابيعه الفكرية والاوربية، وعلى الرغم من إن النزعة الانسانية شكلت في عصرها ثورة فكرية شاملة على المن
... Show MoreThe research aim is to identify the concept of fair value and its measurement approaches, shed light on the concept of fraud and its forms, motives, as well as how to identify fraud under the fair value method.
I have been using the program package SSPS statistical in the calculation of the research variables, and the research sample was a group of university professors and auditors working in the federal board of Supreme Audit.
The researcher has reached some conclusions, the most important; the lack of conclusive evidence about management's intent in adopting the use of fair value raises several doubts about the credibility of the statements prepared in under the fa
... Show Moreالمنظمات الدولية دراسة في منهجها وطبيعة فهمها
The method of request is one of the important rhetorical methods used by the creator in terms of rhetorical diversification, influence, artistic aesthetics and increasing textual coherence, and we tried through a group (Which torments are inferior) by the poet Majid Al-Rubaie, to shed light on these methods and their ability, displacement, relationality, direct and advertising interactions from them, and what they broadcast From metaphorical purposes is the second image of it, after its main image and title. This cohesion and harmony between the two images is an important and influential rhetorical trend.
Dans le romantisme et ses textes, il est important de mentionner qu'il n'existe qu'un seul thème romantique qui est l'amour, mais assez pour avoir fait du XIXème siècle, une révolution du texte romantique. L'amour consiste à la réduction de l'univers, à un seul être, puis la dilatation de ce seul être, voilà l'amour. cet amour passionnel n'est qu'un arrangement froid et réfléchi excluant d'emblée l'exaltation des sentiments. Néanmoins, cet amour passionnel peut être brutal. quant à la mort, dans le drame romantique, l'amour et la mort sont liés. Beaucoup d'histoires d'amour finissent le plus souvent par
... Show MoreThe semiotic approach to the unspoken seeks to analyze the text in an esoteric way, that is, to clarify what is hidden from it by reading between