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MORPHOLOGICAL DESCRIPTION AND COMPARATIVE HISTOLOGICAL STUDY OF THE LIVER IN TWO IRAQI MAMMALS : WEASEL (HERPESTES JAVANICUS) AND EASTERN GRAY SQUIRREL (SCIURUS CAROLINENSIS)
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(Received 21 May 2019, Revised 30 September 2019, Accepted 21 October 2019)ABSTRACT : The results of the current study showed that the liver of H. javanicus appeared as large lobulated organ dividedinto six distinct lobes, that filled the cranial region and little extended to the middle region of abdominal cavity. On the otherhand, liver of S. carolinensis laid against the diaphragm, occupied the cranial region of the abdominal cavity and consisted of fivelobes. The liver is surrounded with a thin capsule of dense regular collagenous connective tissue and few numbers of smoothmuscles fibers can be seen in the capsule that covered the squirrel liver. The liver parenchyma divided into a large number ofinterconnected hepatic lobules marked only by the abundant amount of connective tissue bordered the triads, and within theselobules, polyhedral shaped hepatocytes are arranged as cords of one cell thick. The liver cords are enclosed by irregular hepaticsinusoids and ordered in radial fashion around the central vein. The portal areas are consisting of branches of the hepatic portalvein and hepatic artery as well as (1-4) branches of the bile duct that appear in different sizes.Cuboidal epithelium type is lined the small branches of these ducts, while the large sized of them is lined by columnarepithelium type, in which the goblet cells appeared to be more frequently and clearer in H. javanicus than S. carolinesis. Inweasel, sometimes the triad structures of large and small sized portal areas are embedded together in one abundant mass ofconnective tissue.

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Publication Date
Sat Feb 22 2025
Journal Name
Al-rafidain Journal Of Medical Sciences ( Issn 2789-3219 )
In vivo Brain Pharmacokinetics of Dolutegravir Sodium-Loaded Nanostructured Lipid Carrier in situ Gel: Comparative Study with an Intravenous Drug Solution
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Background: Dolutegravir sodium (DTG), used to treat HIV, faces challenges in delivering effective therapeutic concentrations to the brain due to the blood-brain barrier (BBB). Nanostructured lipid carriers (NLCs) combined with in situ gels present a promising strategy for enhancing brain drug delivery via the intranasal route. Objective: To compare brain pharmacokinetics of DTGs delivered via NLC-loaded in situ gel intranasal administration with the conventional intravenous (IV) drug solution. Methods: 80 Wistar rats, which were divided into three groups: two groups consisting of 39 animals each and a control group with 2 animals. Rats were administered with a dose of 1.0 mg/kg of DTGs IV, and DTGs NLC-loaded in situ gel were admin

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Wed Feb 20 2019
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Wed Sep 02 2020
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A Study of Anti-Fungal Activity for Some Antibiotics Against Aspergillus spp. and Candida spp. in Iraqi patients with Diabetes Mellitus
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Mon Aug 04 2014
Journal Name
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Thu Dec 31 2020
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