خلفية البحث: مع دخول جائحة COVID-19 عامه الثالث ، من الواضح أن آثاره تمتد إلى ما بعد الجهاز التنفسي وهي مهمة سريريًا. قد يكون لهذه العواقب أيضًا تأثير على الصحة ونوعية الحياة. ربما يكون ثلث النساء قد عانين من تغيرات عابرة في أنماط الدورة الشهرية نتيجة للضغوط المرتبطة بوباء COVID-19. وقد يكون هذا التغيير ناتجًا عن التوتر والقلق. يمكن أن يكون عدم انتظام الدورة الشهرية أو غيابها مؤشرًا على انخفاض الخصوبة ، والذي يمكن أن يرتبط بحد ذاته بعدد من الحالات المزمنة ،و قد يتسبب النزيف الحاد في الإصابة بفقر الدم وله تأثير سلبي كبير على نوعية الحياة ويشكل عبئًا اجتماعيًا واقتصاديًا ضخمًا على النساء وأسرهن والخدمات الصحية والمجتمع. الاهداف : ان الهدف من هذه الدراسة هو النظر في تأثير عدوى فيروس كورونا على مستوى الهرمونات للمرأة (استراديول (E2) ، البرولاكتين (PRL) ، الهرمون المنبه للجريب (FSH) ، والهرمون اللوتيني (LH)) ، وكذلك الحالات النزيف الغزير الذي يحدث عند النساء العراقيات قبل انقطاع الطمث المصابات بفيروس كورونا لمدة شهرين إلى ستة أشهر على الأقل. المرضى وطرق العمل/ المواد وطرق العمل: اجريت هذه الدراسة البحثية في مدينة بغداد الطبية (العيادة الاستشارية) ، من تشرين الثاني (نوفمبر) 2021 إلى نيسان (أبريل) 2022. وشملت الدراسة 100 امرأة متزوجة في سن الإنجاب تتراوح أعمارهن بين 18 و 40 سنة. تم تقسيم عينة الدراسة إلى مجموعتين ، المجموعة الاولى 50 امرأة في سن الإنجاب مصابات بالنزيف الحاد بعد الإصابة بـ COVID-19 م لمدة أربعة أشهر على الأقل ، و 50 امرأة غير مصابات بالفيروس التاجي. النتائج: أظهرت نتائج هذه الدراسة ، بمقارنة متوسط ± SD للمجموعتين ، أن مستويات LH كانت ذات دلالة إحصائية عالية لدى النساء اللواتي عانين من نزيف حاد بعد عدوى COVID-19 مقارنة بالنساء غير المصابات بـ COVID-19 ، مع قيمة p 0.000. لم تكن هناك فروق ذات دلالة إحصائية في مستويات FSH بين المجموعتين. كانت مستويات PRL أعلى من الناحية الإحصائية بالنسبة للنساء اللائي عانين من نزيف كبير بعد الإصابة بـ COVID-19 مقارنة بالنساء غير المصابات بـ COVID-19 ، بقيمة p 0.003. كان E2 ذو دلالة إحصائية عالية مقارنة بالنساء اللائي عانين من نزيف مفرط بعد عدوى COVID-19 مقارنة بالنساء غير المصابات. الاستنتاجات: تشير نتائج هذه الدراسة إلى أن النساء بعد الاصابة بـ COVID-19 قد يكون لهن تأثير على أنماط الدورة الشهرية ، ولكن هذا التأثير كان مؤقتًا ويمكن أن يكون بسبب التوتر والقلق الذي يؤثر على HPA ومبايض النساء. قد يؤدي ذلك إلى اضطراب وظائف الجهاز التناسلي الأنثوي ، حيث تظهر مستويات مرتفعة من هرمونات الغدد التناسلية مثل LH و PRL و E2 وأحيانًا تؤدي إلى حالة نزيف حاد بعد الإصابة بفيروس كورونا.
In this study, NAC-capped CdTe/CdS/ZnS core/double shell QDs were synthesized in an aqueous medium to investigate their utility in distinguishing normal DNA from mutated DNA extracted from biological samples. Following the interaction between the synthesized QDs with DNA extracted from leukemia cases (represents damaged DNA) and that of healthy donors (represents undamaged DNA), differential fluorescent emission maxima and intensities were observed. It was found that damaged DNA from leukemic cells DNA-QDs conjugates at 585 nm while intact DNA (from healthy subjects) DNA–QDs conjugates at 574 nm. The obtained results from the optical analyses indicate that the prepared QDs could be utilized as probe for detecting disrupted DNA th
... Show MoreThis investigation reports application of a mesoporous nanomaterial based on dicationic ionic liquid bonded to amorphous silica, namely nano-N,N,N′,N′-tetramethyl-N-(silican-propyl)-N′-sulfo-ethane-1,2-diaminium chloride (nano-[TSPSED][Cl]2), as an extremely effectual and recoverable catalyst for the generation of bis(pyrazolyl)methanes and pyrazolopyranopyrimidines in solvent-free conditions. In both synthetic protocols, the performance of this catalyst was very useful and general and presented attractive features including short reaction times with high yields, reasonable turnover frequency and turnover number values, easy workup, high performance under mild conditions, recoverability and reusability in 5 consecutive runs without lo
... Show MoreIn this study, biodiesel was prepared from chicken fat via a transesterification reaction using Mussel shells as a catalyst. Pretreatment of chicken fat was carried out using non‐catalytic esterification to reduce the free fatty acid content from 36.28 to 0.96 mg KOH/g oil using an ethanol/ fat mole ratio equal to 115:1. In the transesterification reaction, the studied variables were methanol: oil mole ratio in the range of (6:1 ‐ 30:1), catalyst loading in the range of (9‐15) wt%, reaction temperature (55‐75 °C), and reaction time (1‐7) h. The heterogeneous alkaline catalyst was greenly synthesized from waste mussel shells throughout a calcin
Multiple eliminations (de-multiple) are one of seismic processing steps to remove their effects and delineate the correct primary refractors. Using normal move out to flatten primaries is the way to eliminate multiples through transforming these data to frequency-wavenumber domain. The flatten primaries are aligned with zero axis of the frequency-wavenumber domain and any other reflection types (multiples and random noise) are distributed elsewhere. Dip-filter is applied to pass the aligned data and reject others will separate primaries from multiple after transforming the data back from frequency-wavenumber domain to time-distance domain. For that, a suggested name for this technique as normal move out- frequency-wavenumber domain
... Show MoreIn this study, biodiesel was prepared from chicken fat via a transesterification reaction using Mussel shells as a catalyst. Pretreatment of chicken fat was carried out using non‐catalytic esterification to reduce the free fatty acid content from 36.28 to 0.96 mg KOH/g oil using an ethanol/ fat mole ratio equal to 115:1. In the transesterification reaction, the studied variables were methanol: oil mole ratio in the range of (6:1 ‐ 30:1), catalyst loading in the range of (9‐15) wt%, reaction temperature (55‐75 °C), and reaction time (1‐7) h. The heterogeneous alkaline catalyst was greenly synthesized from waste mussel shells throughout a calcin
Abstract
The purpose of our study was to develop Dabigatran Etexilate loaded nanostructured lipid carriers (DE-NLCs) using Glyceryl monostearate and Oleic acid as lipid matrix, and to estimate the potential of the developed delivery system to improve oral absorption of low bioavailability drug, different Oleic acid ratios effect on particle size, zeta potential, entrapment efficiency and loading capacity were studied, the optimized DE-NLCs shows a particle size within the nanorange, the zeta potential (ZP) was 33.81±0.73mV with drug entrapment efficiency (EE%) of 92.42±2.31% and a loading capacity (DL%) of 7.69±0.17%. about 92% of drug was released in 24hr in a controlled manner, the ex-vivo intestinal p
... Show MoreThe largest use of x-ray in medical by dentists, employers or persons that needed by patients with specific conditions, lead to higher exposure of x-ray that may cause many diseases. In the present work radiography films have been used in evaluating the efficiency of using unsaturated polyester polymer reinforced with lead oxide (PbO) as shield material for medical x-ray devices, many parameters studied like concentration and thickness that they are increasing the attenuation of x-ray in them. The results show that the attenuation of X-ray increasing with concentration of reinforced material and with thickness, and the optical density decreases with increasing concentration from 0% to 50%, we chose 30% as suitable concentration to increase
... Show MoreThe effects of nutrients and physical conditions on phytase production were investigated with a recently isolated strain of Aspergillus tubingensis SKA under solid state fermentation on wheat bran. The nutrient factors investigated included carbon source, nitrogen source, phosphate source and concentration, metal ions (salts) and the physical parameters investigated included inoculum size, pH, temperature and fermentation duration. Our investigations revealed that optimal productivity of phytase was achieved using wheat bran supplemented with: 1.5% glucose. 0.5% (NH4)2SO4, 0.1% sodium phytate. Additionally, optimal physical conditions were 1 × 105 spore/g substrate, initial pH of 5.0, temperature of fermentation 30˚C and fermentation dura
... Show MoreSteel-concrete-steel (SCS) structural element solutions are rising due to their advantages over conventional reinforced concrete in terms of cost and strength. The impact of SCS sections with various core materials on the structural performance of composites has not yet been fully explored experimentally, and in this work, both slag and polypropylene fibers were incorporated in producing eco-friendly steel-concrete-steel composite sections. This study examined the ductility, ultimate strength, failure modes, and energy absorption capacities of steel-concrete-steel filled with eco-friendly concrete, enhanced by polypropylene fiber (PPF) to understand its impact on modern structural projects. Eco-friendly concrete was produced by the partial
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