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Novel artificial neural network (ANN) model was constructed for calibration of a multivariate model
for simultaneously quantitative analysis of the quaternary mixture composed of carbamazepine,
carvedilol, diazepam, and furosemide. An eighty-four mixing formula where prepared and analyzed
spectrophotometrically. Each analyte was formulated in six samples at different concentrations thus twentyfour
samples for the four analytes were tested. A neural network of 10 hidden neurons was capable to fit
data 100%. The suggested model can be applied for the quantitative chemical analysis for the proposed
quaternary mixture.