Investigation of GJB2 and SLC26A4 genes related to pendred syndrome genetic deafness patients
(1)
Publication Date
Fri Jul 29 2022
Journal Name
Journal For Vascular Ultrasound
A Comparative Study of the Right and Left Carotid Arteries in Relation to Age for Patients With Diabetes and Hypertension
Introduction:
Introduction: Age
hypertension
and diabetes can cause significant alterations in arterial structure and function
including
changes in lumen diameter (LD)
intimal-medial thickness (IMT)
flow velocities
and arterial compliance. These are also considered
risk markers of atherosclerosis and cerebrovascular disease. A difference between right and left carotid artery blood flow and
IMT has been reported by some researchers
and a difference in the incidence of nonlacunar stroke has been reported between
the right and left brain hemispheres. The aim of this study was to determine whether there are differences between the right and
left common carotid arteries and internal carotid arteries in patients with hypertension and diabetes for 2 age groups.
Methods: We studied 250 patients with both diabetes and hypertension. Patients were divided into 2 age groups with the
old age group being 56 to 75 years and the young age group 35 to 55 years. The bilateral common carotid and internal carotid
arteries were evaluated with B-mode ultrasound and Doppler examinations. The LD and IMT were measured for both common
carotid arteries
and spectral waveform parameters and indices were recorded for both internal carotid arteries.
Results: The difference in LD between the left and right common carotid arteries for the old age group was 11.64% and for the
young age group was 6.42%
with significant P values of <.05 for both age groups. The difference in IMT between the left and
right common carotid arteries was 18.27% in the old age group compared with 15.38% in the young age group
with significant
P values of <.05. There was a difference in peak systolic velocity between the left and right internal carotid arteries of 4.85%
in the old age group which was not significant
compared with 14.28% in the young age group with a significant P value <.05
whereas the difference in end-diastolic velocity between the left and right internal carotid arteries was not significant for both
age groups. Differences between the right and left internal carotid arteries for resistive index
pulsatility index
and pressure
gradient were significant only in the young age group.
Conclusion: We found significant differences between the right and left common carotid and internal carotid arteries in
patients with diabetes and hypertension which were more prominent in the young age group. Values for common carotid IMT
and LD were significantly higher in the left common carotid artery versus the right common carotid artery in both age groups.
Differences between the 2 carotid sides may be attributed to anatomic variations in the common carotid artery origins which
lead to differences in stress between the 2 sides
Age, hypertension, and diabetes can cause significant alterations in arterial structure and function, including changes in lumen diameter (LD), intimal-medial thickness (IMT), flow velocities, and arterial compliance. These are also considered risk markers of atherosclerosis and cerebrovascular disease. A difference between right and left carotid artery blood flow and IMT has been reported by some researchers, and a difference in the incidence of nonlacunar stroke has been reported between the right and left brain hemispheres. The aim of this study was to determine whether there are differences between the right and left common carotid arteries and internal carotid arteries in patient
(7)
(5)
Publication Date
Thu Jun 01 2017
Journal Name
Journal Of Economics And Administrative Sciences
Compared of estimating two methods for nonparametric function to cluster data for the white blood cells to leukemia patients
البيانات العنقودية
الطريقة المقدرات اللبية غير المرتبطة ظاهريا
وطريقة المربعات الصغرى المعممة لمقدرات الشريحة التمهيدية
MSE
MAE
cluster data
the seemingly unrelated Kernel Estimators method
and the Generalized Least Squares Smoothing Spline Estimators method
MSE
MAE.
Abstract:
We can notice cluster data in social, health and behavioral sciences, so this type of data have a link between its observations and we can express these clusters through the relationship between measurements on units within the same group.
In this research, I estimate the reliability function of cluster function by using the seemingly unrelate
... Show More
Publication Date
Thu Jun 13 2024
Journal Name
Al-rafidain Journal Of Medical Sciences ( Issn 2789-3219 )
Association of the MDR1 Variants (rs2032582 and rs2032583) with Steroid Response in Iraqi Children with Idiopathic Nephrotic Syndrome
Background: Several studies linked the development of steroid-resistant nephrotic syndrome (SRNS) to genetic variations in the multidrug resistance 1 (MDR1) gene, though a disparity in findings was underlined among children with different ethnic origins. Objective: This study examined the relationship between MDR1 variants (rs2032582 and rs2032583) and the risk of developing SRNS in Iraqi patients with idiopathic nephrotic syndrome (INS). Methods: This case-control study included children with steroid-sensitive INS (SSNS; n=30) and SRNS (n=30) from the Babylon Hospital for Maternity and Pediatrics. Sanger sequencing was used to determine the participants’ genotypes. Results: The rs2032582 genotypes and alleles were not associated
... Show More
Publication Date
Mon Nov 11 2019
Journal Name
Day 3 Wed, November 13, 2019
Drill Bit Selection Optimization Based on Rate of Penetration: Application of Artificial Neural Networks and Genetic Algorithms
Abstract<p>The drill bit is the most essential tool in drilling operation and optimum bit selection is one of the main challenges in planning and designing new wells. Conventional bit selections are mostly based on the historical performance of similar bits from offset wells. In addition, it is done by different techniques based on offset well logs. However, these methods are time consuming and they are not dependent on actual drilling parameters. The main objective of this study is to optimize bit selection in order to achieve maximum rate of penetration (ROP). In this work, a model that predicts the ROP was developed using artificial neural networks (ANNs) based on 19 input parameters. For the</p>
... Show More
(13)
Publication Date
Tue Jun 30 2015
Journal Name
Al-kindy College Medical Journal
Estimation of vitamin E level and its relation to lipid profile in patients with type II Diabetes Mellitus
DM type II
Vitamin E
Dyslipidemia
diabetes mellitus
Background: Type 2 diabetes mellitus (T2DM) is considered a global disease as it affects over 150 million people worldwide, a number that is supposed to be doubled by 2025. High glucose levels, in vitro, appear to raise the extent of LDL oxidation, and glycated LDL is more prone to oxidative modification.Objective: To investigate the relationship between serum level of vitamin E and lipid profile in patients with type II DM.Methods: This study involved 28 patients suffering from type II DM diagnosed 1-4 years ago and with age ranged from 17 -60 years old, with different residence around Basra ; In addition to 56 apparently healthy persons matched in age and sex to the patients as a control group. The medical histories were taken and Gene
... Show MorePublication Date
Mon Feb 15 2021
Journal Name
Nursing Open
Recitation of quran and music to reduce chemotherapy‐induced anxiety among adult patients with cancer: A clinical trial
Abstract<sec><title>Aim Design Methods
Cancer
Chemotherapy
Anxiety
Quran
Music
Care
The aim of this study was to assess the effectiveness of listening to music or Quran in reducing cancer patients’ anxiety before chemotherapy administration. Reducing anxiety in people with cancer, prior to chemotherapy administration, is a crucial goal in nursing care.
An experimental comparative study was conducted.
A simple randomization sampling method was applied. Two hundred thirty‐eight people with cancer who underwent chemotherapy were participated. They are assigned as Quran, music and control groups.
(20)
(21)
Publication Date
Tue Mar 19 2019
Journal Name
Tikrit Journal For Agricultural Sciences
Dependence and Phenotypic and Molecular Labels in Estimations of Genetic of Variance of
Some Genotypes of Corn (Zea mays L.)
Performance of genotypes
SSR
Maize.
Afield experiment was conducted in the college of Agriculture labs Sulaimanya University in 2014 to estimate the genetic variance between 12 genotypes of maize. (SSR) technology was used depending on (PCR) technology. Twenty primers were used for the genetic variance analysis between the studied genotypes and 15 primers showed polymorphic results in repeated experiment caused to experinse 52 alleles which gave 307 bands of range 3.1 by different molecular sizes ranged between 80-1000 pair base the value of PIC reached to phi069 gave high value (0.8785), the range of genetic diversity for studied genotypes reached to (0.625) gave primers pairs phi069 hig value for genetic diversity (0.888). The value of total allele replication ranged at pri
... Show MorePublication Date
Sun Jul 12 2020
Journal Name
Medico-legal Update
Assessing the Response of a Sample of Iraqi Asthmatic Patients to Different Medication Regimens
Persistent asthma
Medication regimens
Tiotropium
Asthma is a chronic inflammatory disease of respiratory airways characterized by distinctive history of respiratory symptoms due to variable airflow obstruction which reverses either spontaneously or in response to certain medications. Acetylcholine is a parasympathetic neurotransmitter which plays fundamental roles in the development of persistent asthma. Treatment guidelines recommend using medium doses of inhaled corticosteroids in addition to another controller bronchodilator instead of using high doses inhaled steroid alone for treatment of moderate to severe persistent asthma. The inhaled long acting muscarinic antagonist, tiotropium, was approved recently to control unresponsive asthma to inhaled corticosteroid with or without a long
... Show More
(2)
Publication Date
Sun Dec 27 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
CYP2D6 Genotype in Relation to Liver Toxicity Due to Tetrabenazine in Iraqi Patients with Hyperkinetic Movement Disorders
Dystonia
chorea
Tetraberazine
Alpha and Beta dihydrotetrabenazine
CYP 450 2D6 enzyme polymorphism
liver function.
Abstract
The common types of movement disorders are ; dystonia which is a syndrome of repetitive muscle contractions. While , Huntington disease is autosomal dominant progressive neurodegenerative disorder, which is characterized by involuntary movements (“chorea”).
Tetrabenazine therapy has been shown to effectively control this movements compared with placebo.
Design the proper dosing approach for patients treated with tetrabenazine with genotype polymorphisms and their hepatic effect on patients.
A prospective case controlled study was carried on 50 patients whom divided into 2 groups :first group involved 25 patients who had cho
... Show More
Publication Date
Fri Apr 30 2021
Journal Name
Onkologia I Radioterapia
The prevalence of lymph proliferative disorders in a group of Iraqi patients and its relation to blood indices parameters
lymphoproliferative disorders
Abstract: Lymphoproliferative Disorders (LPDs) are a group of neoplasms affecting various cells within lymphoid system. Each type has different treatment a..70619
(1)