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Clinical and Pathological Characteristics of Triple Positive Breast Cancer among Iraqi Patients
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Background: Breast cancer is the most common malignancy affecting the Iraqi population and the leading cause of cancer related mortality among Iraqi women. It has been well documented that prognosis of patients depends largely upon the hormone receptor contents and HER-2 over expression of their neoplasm. Recent studies suggest that Triple Positive (TP) tumors, bearing the three markers, tend to exhibit a relatively favorable clinical behavior in which overtreatment is not recommended. Aim: To document the different frequencies of ER/PR/HER2 breast cancer molecular subtypes focusing on the Triple Positive pattern; correlating those with the corresponding clinico-pathological characteristics among a sample of Iraqi patients diagnosed with the disease. Patients and Methods: This retrospective study involved 570 female patients diagnosed with breast cancer who visited the Main Referral Center for Early Detection of Breast Cancer and the National Cancer Research Center. The requested data was mainly extracted from an established information system database, developed by the principal author over a 4-years period from 2012 to 2016. The registered information comprised data related to clinical presentation, diagnostic and pathologic findings. ER, PR and HER2 status were analyzed immunohistochemically and the detected profiles were correlated with the corresponding clinico-pathological characteristics. Results: The rates of ER (+), PR (+) and HER-2 (+) tumors were 66.8%, 64% and 29.3% respectively. The tumor marker expression status was documented in eight subtypes; 83 cases (14.6%) of the examined breast carcinomas were categorized as ER+/PR+/HER2+ (Triple Positive/Luminal B), 89 cases (15.6%) were ER-/PR-/HER2- (Triple Negative), 241 (42.2%) were ER+/PR-/HER2- (Luminal A) while 67 (11.8%) showed ER-/PR-/HER2+ expression (HER-2 variant). No significant variations were noted when comparing age, menopausal status and tumor grade of Luminal B pattern to Luminal A and the rest of the studied subtypes. Although our data revealed a statistical difference with respect to the distribution of tumor types; where infiltrative ductal carcinoma constituted the major histology among patients with Triple Positive/Luminal B subtype (86.7% as compared to 67.6% in Luminal A), nevertheless, more than two third of those patients (67.4%) were diagnosed at earlier stages (I and II) compared to 55.2% of those in the remaining groups. Conclusions and Recommendations: Our findings support the hypothesis that the Triple Positive subtype might be driven primarily by the hormone receptor status. Further comprehensive surveys are recommended to focus on the intrinsic interactions and tumor cell heterogeneity of that pattern to avoid overtreatment and predict accurate response to therapy.

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Publication Date
Wed Jul 01 2020
Journal Name
Journal Of Controlled Release
Breast intraductal nanoformulations for treating ductal carcinoma in situ I: Exploring metal-ion complexation to slow ciclopirox release, enhance mammary persistence and efficacy
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Publication Date
Wed Dec 12 2018
Journal Name
Iraqi National Journal Of Nursing Specialties
Stress and Its Associated Factors among Students of the College of Nursing University of Baghdad
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Objectives: The current study aims at identifying the level of perceived stress among nursing college students and determining the factors associated with stress they have. Methodology: A cross-sectional descriptive study initiated for the period on November 1st, 2014 to May 1st, 2015. The study has been conducted on the undergraduate nursing college students / University of Baghdad. The sample of the study was consisted of (128) students who were selected purposively. The questionnaire of the study was adopted and modified for the present study which consisted of socio-demographic data and the scale of

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Publication Date
Wed Mar 23 2022
Journal Name
Journal Of Educational And Psychological Researches
Introspective Awareness among College Students
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The current study aims to identify the introspective awareness of the study sample, as well as to identify the introspective awareness of the study sample in terms of gender. The researcher adopted the viewpoint of Mehling (2002) as a theoretical framework for Introspective awareness. A sample of (239) male students and (331) female students were chosen randomly from two universities (Baghdad University and Al- Mustansiriyah University). To achieve the objectives of the research, the researcher adopted a vulgar scale (Mehling, 2012), which in its final form consisted of (32) items distributed into eight domains. As for the reliability coefficient of the scale, it reached (0.896) in the Cronbach alpha equation. The study revealed that the

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Publication Date
Wed Oct 18 2023
Journal Name
Iraqi National Journal Of Nursing Specialties
Job Satisfaction among Nursing Staff
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Objectives: The specific objectives of the present study were to assess the level of job satisfaction among
nursing staff who are working in the Ministry of Health and Ministry of Higher Education and Scientific
Research in the provinces of Erbil, Mosul and Kirkuk to determine the factors that affect their satisfaction.
Methodology:٨
descriptive design was carried-out from September 20, 2006 through April 1,'؛ 2007 in order
to assess the job satisfaction for nursing staff in governmental health agencies and educational setting.
Quantitative research methods were utilized to employ the study design. The study was conducted on three Iraqi
governorates (Mosul, Kirkuk, and Erbil). The sample of the study was collected

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Publication Date
Sun Apr 03 2016
Journal Name
Journal Of Educational And Psychological Researches
KINDNESS AMONG FEMALE UNIVERSITY STUDENTS
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The research aims at constructing a Scale of Kindness phenomenon among university female students and elicit criteria to it, It also recognizes the differences in kindness levels among female students according to variables (specialization, academic grade, social status, and the age). The sample consists of 534 female students who were selected randomly. The two researchers rely on experience and the results of questionnaire, The questionnaire is given to 130 female university students from different colleges as well as their acquaintance with literary works witch dealt with kindness , The scale consists of 39 items , It has psychometric characteristics (Validity and Reliability) . The criterion (Z) is extracted from it and throu

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Publication Date
Wed Jun 07 2023
Journal Name
Journal Of Educational And Psychological Researches
Mental Fatigue among University Teachers
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The current research aims to measure the level of mental fatigue among the teachers of the University of Baghdad, as well as to measure the significant differences according to the variable of mental fatigue in terms of male and female teachers, specialization (humanitarian, scientific), and title (professor, assistant professor, lecturer). To achieve these current goals, a random sample of (300) teachers from University of Baghdad was selected for the academic year 2019-2020. To measure the mental fatigue, the researcher developed a tool to measure the variable included (56) items. The research revealed that the study sample is mentally tired, the female sample is more mentally tired than males, there are no statistically significant di

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Publication Date
Tue Jan 02 2018
Journal Name
Journal Of Educational And Psychological Researches
Masculine identification among secondary schoolboys
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The purposes of this study are to measure masculine's identification among secondary school students, and to examine the significant differences among secondary school students in respect of students age (16-18) year. The researcher has prepared a questionnaire comprised (25) item to measure masculine identification among students: this scale was applied on (100) student who were selected as a sample from four different school at al-rusafa side in Baghdad. The scale then modified to (23) item to be more consistent. The results revealed that there were no significant differences among students based on the variable of age, and the mean of masculine identification showed a high level than the hypothesized mean.

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Publication Date
Mon Jul 15 2024
Journal Name
مجلة الدراسات المستدامة
Cyberbullying among academically superior students
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Results: The results summarized two goals, the first goal stipulates (to identify the degree of cyberbullying among academically outstanding students in the middle school stage). To achieve this goal, the researchers applied the research tool (electronic bullying scale) and then extracted the arithmetic mean for the sample of the current research, which amounted to (6.28) with a standard deviation of (4.03). Then the researchers applied the t-test for one sample to identify the significance of the differences between the means. The arithmetic mean for the sample and the hypothetical (theoretical) mean, which amounted to (11.5) degrees, and after applying the T-test for one sample, it was found that the calculated T-value, which amounted to

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Publication Date
Sun Oct 01 2017
Journal Name
Journal Of Educational And Psychological Researches
Cyber bullying among college students
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The current research aimed to explore the practicing of cyber bullying among college students as well as the differences of practicing cyber bullying among university students based on gender variable. The finding revealed that there was a high prevalence rate for cyber bullying among research sample who was students from Baghdad University. It assured clearly that this group participated in cyber bullying effectively, due to the biological and psychological factors which make them super sensitive toward the social and economic problems. Moreover, the results showed that there were significant differences between male and female in practicing cyber bullying. The study proved that women use cyber bulling more than men.  

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Publication Date
Tue Jan 02 2018
Journal Name
Journal Of Educational And Psychological Researches
Voluntary work among university students
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This research aims to identify the level of Voluntary work among university students, and explore the statistical differences of voluntary work among students due the gender and major. A total of (400) male and female student from morning study were selected as a sample to achieve the research's objectives. Al-Malaki (2010) scale was adopted to collect the required data. The results revealed that men take massive part in voluntary work than women, and students of human sciences showed significant differences than those of other majors.   

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