Background: There were definite changes in pathologies involving thyroid gland allover the world with increasing incidence of thyrotoxicosis and differentiated malignancies.
Patients and methods: 224 patients were operated upon by the same surgeon during 15 years period. Those patients were divided into two groups (GI from June 1990 up to June 2000) and (GII from June 2000-June 2005).
Results: female to male ratio was 3.3:1. The most common presentation among both groups was Multinodular goiter (MNG) 76.8%. toxic goiter was recorded in 24% of patient with increase among GII patients. A significant effect of stress on the increasing incidence of thyrotoxicosis was elicited in more than 50% of patients w
Propolis is a complex resinous bee product that has a wide range of biological activities. In the present investigation, two oral doses (10 and 20 mg/kg/day) of propolis (ethanol extract) were evaluated immunologically in albino male mice (80 animals) through three types of experiments. In the first, the propolis was tested alone, while in the second and third experiments, propolis was given before and after the immune suppressive drug MMC (pre- and post treatments, respectively). The three experiments were paralleled with three negative controls, in which the propolis was replaced with distilled water. In the first experiment, the dose 10 mg/kg of propolis enhanced the parameters investigated, and a si
... Show MoreBagkground:Chlorpromazine is widely used in human medicine in the therapy of schizophrenia, organic psychosis and the manic phase of manic depressive illness. It expressed a selective cytotoxicity and the results of genotoxicity were positive.
Objectives: This study is designed to explore the effect of chlorpromazine on irradiated and non irradiated calf thymus double strands DNA (ctdsDNA) molecule.
Methods: Aliquots of irradiated (subjected to UVB light) and non-radiated ctdsDNA samples were incubatyed with different concentrations of chlorpromazine. Further series of experiments studied the simultaneous effects of chlorpromazine and UVB light on aliquots of ctdsDNA, The changes in optic densities of
Background : It had been indentified by histological, histochemical and morphometrical studies that peganum harmala is a mammogenic herb and borage officinalis is a lactogenic one . To complete our investigation about these two herbs , we performed electron microscopical study.
Materials and methods : Rats were grouped according to their physiological status into three groups . Each group was subdivided in to three subgroups : one control and two experimental . The two experimental group were treated daily; the 1st one with an aqueous extract of peganum harmala seeds and the 2nd with an aqueous extract of borage officinalis flowers . After two weeks of treatment , mammary glands were employed for electron
الخلفية :تعتبر الحالة المؤكدة من عدوى فايروس ( H1N1 ) لشخص يعاني من أعراض تشبه الإنفلونزا ويؤكد الفحص المختبري وجود فايروس ( H1N1 ) عن طريق فحص تفاعل البلمرة المتسلسل - الوقت الحقيقي RT- PCR أو زرع الفيروس .
أهداف الدراسة : لتحديد الخواص الديموغرافية والوبائية والسريرية لإنفلونزا H1N1 في الأطفال الذين أدخلوا المستشفى يعانون من اعراض الانفلونزااثناء فترة الوباء.
... Show Moreالخلفية: يعرف إلتهاب الفقار اللاصق أيضا بإسم إلتهاب الفقار الفقاري المحوري الشعاعي؛ وهو مرض وراثي نادر يصيب الأشخاص الذين يعانون من عوامل وراثية؛ بالإضافة إلى ذلك فهو أحد أمراض المناعة الذاتية مع تفاعلات التهابية مزمنة تقدمية. يشمل علاج إلتهاب الفقار اللاصق تعديل نمط الحياة واستخدام الأدوية مثل العامل البيولوجي إنفليكسيماب أو البديل الحيوي CT-P. على الرغم من فائدتهما العلاجية ترتبط هذه العلاجات ب
... Show Moreالخلفية: الميثوتريكسات هو مضاد للفولات يستخدم على نطاق واسع في السرطانات والأمراض الالتهابية أو المناعة الذاتية ، ومن المعروف أيضًا أنه يمنع استخدامه أثناء الحمل والرضاعة ولا ينصح به للمرضى الذين يخططون لأن يكونوا آباء لأن له تأثيرًا ضارًا على الجنين. والغدد التناسلية.
يمكن تقييم وظيفة المبيض من خلال معايير معينة مثل مستويات الهر
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الخلفية: أكثر من 100 مليون شخص في جميع أنحاء العالم (6٪ من السكان) يعانون من مرض السكري ، وهو أكثر أمراض الغدد الصماء انتشارًا. ينتج عن عدم قدرة البنكرياس أو ضعف قدرتها على انتاج ما يكفي من الأنسولين ، مما يرفع مستويات الجلوكوز في الدم. بالإضافة إلى ذلك ، فإن مرض السكري من النوع 2 هو الحالة الأكثر ارتباطًا بالسمنة من جميع الاضطرابات ، وبحلول عام 2025 ، من المتوقع أن يتضاعف عدد الأشخاص المصابين بمرض السكري ا
... Show MoreBackground: Activin A (ACV-A), a member of the transforming growth factor-beta (TGF-beta) superfamily that regulates follicular growth hormone (FSH) secretion and initiates intracellular signaling pathways, is essential to reproductive regulation. ACV-A is involved in regulating cellular proliferation, differentiation, apoptosis, and homeostasis, among other biological processes. The pituitary gland, the gonads, and other organs all secrete ACV-A, which is made up of two beta A (βA) subunits.
Objectives: To compare the serum concentrations of ACV-A in women diagnosed with missed abortion (MA) or ectopic pregnancy (EP) with those of healthy controls.
Methods: The study was
... Show Moreهدف الدراسة: مقارنة النتائج الولادية الحاصلة في الحمل الذي يلي ولادة ميتة مع تلك الحاصلة عقب ولادة حية.
نوع الدراسة: دراسة وصفية مقطعية.
مكان الدراسة: مستشفى بغداد التعليمي من آذار لسنة ۲۰۰۸ ولغاية نيسان ۲۰۰۹
تصميم البحث: قمنا بجمع النساء خلال فترة حملهن الثاني. النساء اللاتي حملن بعد ولادة ميتة (رۥمزن بالمجموعة المعرضة) واللاتي حملن عقب ولادة
... Show Morestudents may knowledge of facts but they can not apply them, so they have the knowlege but they do not have enough of skills.
Background: Substance use disorders (SUDs) are among the common psychiatric disorders and constitute a major public health concern. Iraqi’s were exposed to widespread violence and wars in the last decades. High prevalence of alcohol and substance use was reported recently in Baghdad. Research literature documented the association of SUDs with exposure to trauma events e.g. wars, terrorist attacks and natural disaster. Published articles on SUDs among prisoners in Iraq are scarce. Therefore, this work was carried out to report on SUDs among prisoners in Al-Diwania governorate and its relation to antisocial activity.
Methods: A total of 1200 prisoners in Al-Diwania civilian prison were included in the stu
Background: Cardiovascular diseases are among the most common cause of death in Developed countries. In addition to traditional risk factors for cardiovascular disease, nowadays, accumulating evidence indicates that a variety of infectious agents may contribute to pathogenesis of ischemic heart disease.
Patients and methods: 125 patients (25 females and 100 males) attending the department of cardiology, Baghdad, teaching hospital over the period December 2008- June 2009were enrolled. Their age range between (39-75 years) compared with 50 healthy individuation (Age & sex matched). The sera were tested for H. pylori antibodies using enzyme linked immunosorbent assay (ELISA).
Results: 80% of pa
Abstract
this is a case report of abdominal cocoon also referred to as sclerosing encapsulating peritonities in 32 year-old female patient who presented to us with history of recorrent abdominal pain ,
Background: Necrotizing fascitis is a progressive, rapidly spreading inflammatory infection located in the deep fascia, with secondary neerosis of the subcutaneous tissues polymicrobial infection is the most common finding in necrotizing fascitis rather than a single caustive organism.
Background: laparoscopic cholccystectomy (LC) gained a wide acceptance as treatment of choice for acute cholccyslitis (AC) as early in 72 hours of admission or after interval of 8-12 weeks after the patient treated by medical treatment.
Background: Foreign body impaction in the esophagus is a common problem. Our Objective is to draw conclusions from a retrospective over viewing a number of cases to assess current methods of management and to come out with recommendation from collected experience.
Patient and method: A retrospective study of (62) patients admitted to the Department of Thoracic and Cardiovascular Surgery at Medical City Teaching Hospital from January 2002 to December 2004 with history of foreign body swallowing and impaction. Six patients excluded from the (62) patients after having negative esophgoscpic findings. On presentation, history about type and time of ingestion, associated signs and symptoms were recorded, x- ray
الخلفية : التغيرات التي تحدث في في قابلية التخثر و النزف قد بينت في مرضى فقر دم البحر المتوسط نوع ب زيادة وقت البروثرومبين و البروثرومبين الجزئي و نقصان مستوى عوامل التخثر و مضادات التخثر الطبيعية قد بينت بصور مختلفة عن طريق الية تشمل زيادة قابلية حدوث خثرة دموية في بعض مرضى فقر دم البحر المتوسط و اصبحت واضحة تماما .
الاهداف : لتحليل التغيرات في قابلية التخثر و
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الخلفية: إلتهاب المفاصل الروماتويدي هو مرض إلتهابي مجهول السبب مرتبط بالتهاب المفاصل ووجود أجسام مضادة ذاتية، معظمها أجسام مضادة للببتيد الستروليني الحلقي تُطلق عندما يفقد الجسم قدرته على التمييز بين الجزيئات الذاتية والغريبة. الأميلويد المصلي A2 هو بروتين ينتج في الطور الحاد إستجابة للظروف الإلتهابية بما في ذلك إلتهاب المفاصل الروماتويدي.
الأهداف: للتحقيق في القدرة ا
... Show Moreالخلاصة:
خلفية البحث: تعتبر الرعشات من أكثر مشاكل الحركة شيوعًا في الممارسة السريرية. وتعرف ب التذبذبات المتكررة واللاإرادية. يمكن أن تستغرق عملية التشخيص لمرضى الرعاش وقتًا طويلاً ومعقدة ، لأن تحديد الرعاش الأساسي وتمييزه عن الأنواع الأخرى من الرعاش يمكن أن يكون مستهلكًا للوقت ومعقدًا.
الأهداف: باستخدام التخطيط الكهربائي السطحي للعضلات ومقياس التسارع ، هدفت ه
... Show MoreBackground: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune illness. Oxidative stress such as Malondialdehyde plays a major role in the pathophysiology of RA while antioxidants such as Coenzyme Q10 play protect role against inflammation.
Objectives: The study aimed to compare serum concentrations of Coenzyme Q10 and Malondialdehyde in rheumatoid arthritis patients and healthy controls and to evaluate how different types of treatment (biologics and chemotherapy) influence serum levels of them in this disease.
Methods: The case-control study was conducted on 88 individuals (60 had been diagnosed with rheumatoid arthritis and 28 healthy as (Controls). The pati
... Show MoreBackground: Wilms' tumor and Neuroblastoma are common pediatric malignancies, with biochemical markers like plasma metanephrines and serum lactate dehydrogenase (LDH) being studied for diagnostic and prognostic values. Metanephrine, a catecholamine metabolite, is elevated in Neuroblastoma due to tumor secretion. Elevated LDH levels may correlate with tumor burden and indirectly indicate disease activity.
Objectives: To evaluate plasma metanephrine and lactate dehydrogenase as biomarkers in Neuroblastoma and Wilms tumor in pediatric patients.
Methods: The study was conducted between February and December 2024, in the Children Welfare Teaching Hospital, Medical C
Background: Polycystic Ovary Syndrome (PCOS) is a prevalent endocrinology disorder affecting women in the years of reproduction. Malondialdehyde (MDA) is a result of polyunsaturated fatty acid peroxidation and is widely utilized as a trustworthy indicator of peroxidation of lipids and oxidative damage. Conversely, Vitamin D deficiency is a global issue affecting around one billion individuals. 25-hydroxyvitamin D₃ is linked to multiple metabolic processes and reproduction facets of women with PCOS and thus may contribute to the PCOS pathophysiology.
Objectives: To measure and compare serum malondialdehyde levels and 25-hydroxyvitamin D₃ concentrations between women with polycystic ovary syndrom
Background: The prevalence of multidrug-resistant bacteria has demonstrated a need to develop and use alternative antimicrobial agents. There has been a growing interest in medicinal plants and herbs and their extracts.
Objective: To identify the antibacterial and anti-biofilm activity of aqueous and alcoholic extracts of the Fenugreek (Trigonella foenum-graecum L.) seed against multidrug-resistant clinical bacterial isolates (Gram-positive Staphylococcus aureus and Gram-negative Acinetobacter baumannii).
Methods: Aqueous and alcoholic extracts were prepared from the seeds of the Fenugreek (Trigonella foenum-graecum L.) plant. A gas chromatog
Background: Chronic gastritis (CG) is histopathological entity characterized by chronic inflammation of the stomach that mostly caused by Helicobacter pylori, development of
inflammation in gastric mucosa result in release of pro- and anti- inflammatory cytokines .This study aimed to shed light on the role of cytokines (IFN-γ, IL-8, IL-4, IL-10, and GM-CSF) in the
development and prognosis of CG among Iraqi patients.
Patients and methods: 100 Iraqi patients with CG (61 male and 39 female) with age range (10-79) year, were involved in this stady while attending Specialist Hospital of Disease of Liver and Gastrointestinal System at Baghdad Medical City from Nov. 2007 to Apr. 2008. Patients divided accordi
Background: Acute myocardial infarction (AMI) is an irreversible myocardial injury and necrosis caused by serious and long term ischemia. Fibrinogen is considered as
one of the probable risk factors of myocardial infarction.
Patients and methods: 1.8-mL venous blood specimen from 40 patients with MI and 50 control subjects was obtained and put it into tubes containing 0.2 mol/L trisodium citrate. Plasma fibrinogen level was determined by the method of Clauss (Diagnostic Stago, France).
Results The mean age of patients was (45.2 ± 6) years in patients with premature myocardial infarction and (45.06±5) years in the control group (p =0.07). There were no statistically significant relationships between the
Background: Assessment of fracture healing is a common problem in orthopedic practice and research. Computerized Tomography (CT) is a reliable tool for quantification of the fracture repair process in experimental animals. Histomorphometric evaluation provides a clear quantitative evidence of the bone healing process. The evaluation by micro-architectures in healing bone showed variable correlation between CT and histomorphometry.
Material and methods: open ulnar osteotomy induced in twenty young male rabbits under general anesthesia without internal fixation, and divided into five groups. A group of animals were sacrificed at end of 2nd week, 3rd week, 4th week, 5th week, and 6th week. The right ulna iso
التمزق التلقائي لأغشية الجنين قبل بدء الولادة الذي يحدث قبل اكتمال 37 أسبوعًا من الحمل ، يشار إليه على أنه تمزق الأغشية المبكر قبل الولادة . يحدث في 2٪ من حالات الحمل. يعتمد التنبؤ بـه على تحديد عوامل الخطر المرتبطة واستخدام مؤشرات حيوية محددة لمنع النتائج الضارة على الام والجنين. ان الهدف من الدراسة لمعرفة العلاقة وفهم الدور بين حامض الفوليت ، فيتامين بي 12 والهميوسستين في تمزق الغشاء الامينوسي المبكر قبل حدو
... Show MoreBackground: The management of patients with inflammatory bowel disease (IBD) must take mental health into account because it might be difficult to find the best therapies and mental health resources. Anxiety and depression are the two psychological illnesses that IBD patients experience most frequently. The growing incidence of these mental illnesses encourages mental screening of every IBD patient at the initial session. There are easy-to-use, scientifically effective screening techniques for mental health issues. As important as or even more so than a therapy modality may be psychological techniques.
Objective: To assess the level of depression among IBD patients in the Gastroenterology and Hepa
... Show Moreخلفية البحث: مع دخول جائحة COVID-19 عامه الثالث ، من الواضح أن آثاره تمتد إلى ما بعد الجهاز التنفسي وهي مهمة سريريًا. قد يكون لهذه العواقب أيضًا تأثير على الصحة ونوعية الحياة. ربما يكون ثلث النساء قد عانين من تغيرات عابرة في أنماط الدورة الشهرية نتيجة للضغوط المرتبطة بوباء COVID-19. وقد يكون هذا التغيير ناتجًا عن التوتر والقلق. يمكن أن يكون عدم انتظام الدورة الشهرية أو غيابها مؤشرًا على انخفاض الخصوبة ، و
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