Background: Growth hormone is a hormone responsible for the normal body growth and development by stimulation protein production in muscle cells and
energy release for breakdown of fat. On the other hand leptin is a newly discovered hormone that is mainly synthesized in adipose tissues it decreases food intake by
causing satiety and promoting energy combustion . Both aging and obesity are associated with a reduction in growth hormone secretion. In the mean time obese
humans have increased circulating leptin.
Objective: The aim of this paper is to shed light on the contribution of these two hormones in the mechanism of aging process in an attempt of improving this
process for a better life at old ages.&n

Background: genital herpes simplex virus infection in pregnancy poses a major risk to the fetus and it has been associated with bad obstetric out come causing preterm labor, intrauterine growth retardation and spontaneous abortion. This study was conducted to determine if premature rupture of membranes before 37 weeks of gestational age are observed with subclinical shedding of herpes simplex virus (HSV).
Patients and methods: Cervical swabs were taken from 75 women with a history of preterm premature rupture of membranes before 37 weeks of gestation, and 20 women with normal
obstetrical history for the presence of HSV antigen using Enzyme linked Immuno Sorbent Assay (ELISA) method.
Results: HSV ant

Background: Thrombocytopenia is the second most common hematological abnormality in pregnancy following anemia. However, its incidence causes and outcomes received scarce attention, particularly in developing countries like Iraq.
Objective: This study was conducted to determine the incidence, causes and consequences of thrombocytopenia on both the mother and fetus.
Material and Methods: Platelet counts were performed on 600 pregnant women in their third trimester and on 200 age matched non pregnant healthy women, as well as 150 of the newborns of the former groups.
Results: The overall incidence of thrombocytopenia in pregnancy was 8.6%, with the gestational thrombocytopenia implicated in 76.9%,. Hy

Background: Ulcerative colitis is a chronic inflammatory bowel disease (IBD); its extragastrointestinal manifestations vary from one country to another. This study identifies the prevalence of the extragastrointestinal manifestations in a sample of Iraqi patients with ulcerative colitis and their relation to disease activity.
Patients and Methods: A descriptive study was conducted on 100 patients with established diagnosis of ulcerative colitis, who attended Baghdad Teaching hospital and Gastroenterology center in Baghdad during the period from May 2009 to January 2010. A direct interview and thorough clinical examination were done to determine the history of the disease, its severity and the presence or

Background: Ulcerative colitis is a chronic idiopathic inflammatory disorder that affects the rectum & extends proximally to affect variable extent of the colon. Autoimmune hemolytic
anemia had reported in few cases.
Objective: to determine the prevalence of autoimmune hemolytic anemia in Ulcerative colitis.
Patient & Methods: Fifty Iraqi patients having Ulcerative colitis attending the GIT Center in Baghdad during the period from March to August 2004 were interviewed, examined and
diagnosed according to pathological study done for colonic biopsies by the same centre. Blood was drown for the assessment of complete picture with blood film, reticulocyte
percent, erythrocyte sedimentation rate, Coo

Background: stress test (EST) is one of the main diagnostic and prognostic tests for ischemic heart disease. However, its usefulness depends on achieving target heart rate, then chronotropic incompetence and poor exercise capacity limits its utility. We evaluated the usefulness of atropine administration during the EST to decrease the number of tests with inconclusive results in these patients.
Patients &Methods: We carried out this study in Ibn AI-Bitar Teaching Hospital from September 2007 to December 2008 and comprised of 210 patients undergoing EST. In subjects experiencing fatigue when they achieved 50-75% of target heart rate (THR), or those who failed to achieve their THR, atropine was adm

Background: Prognostic histological evaluation of many cancers have recently concentrated on angiogenesis.
Materials &Methods: A total of twenty formaline-fixed, paraffin embedded blocks of renal cell carcinoma were included in this study. Sections were subjected for immunohistochemical staining of CD34. The median of the MVD of all cases of RCC were obtained to divide the cases into high- and low-MVD score groups and were correlated with the tumor stage and grade.
Results: there was a significant correlation of the high MVD score with tumor stage (P=0.02).
Conclusion: MVD may be considered as a potential prognostic marker for RCC.

Background: there are different procedures for the diagnosis of females suspected with toxoplasmosis. However, time, cost, and accuracy of the test should meet patient’s needs.
Material and methods: one hundred and eleven female with suspected toxoplasmosis were under go three different procedures for the diagnosis of Toxoplasma gondii infection. Latex agglutination test, rapid chromatographic (immunoblot) and ELISA test were done for all patients. The results were described as frequency and percentage of positivity; also, specificity and sensitivity of immunoblot were assessed according to the result of other tests.
Results: The Latex test has shown 80% and 61.54% sensitivity and specificity respectively

المقدمة: التهاب القولون التقرحي :هو التهاب مزمن غالبا ما يصيب منطقة المستقيم ينتج عنة تقرحات في منطقة المستقيم من الممكن ان تمتد لتشمل المناطق المتبقية من الأمعاء الغليظة بطريقة متواصلة  ويتميز بفترات من الشفاءاو تفاقم في الالتهاب .

وجد ان E.histolyticaاحد المسببات عند المرضى المصابين بالتهابات القولون التقرحية .ان التهاب الأمعاء الأميبي هو التهاب مزمن يصيب الأمعاء مصاح

Back ground : Chronic renal failure (CRF) is characterized by progressive destruction of renal mass with irreversible sclerosis and loss of nephrons over a period of at least months to many years which is treated either by dialysis which includes hemodialysis (HD) and peritoneal dialysis (PD) or renal transplantation.
Objective : To document the elevation of interleukin-6 (IL-6) in Iraqi HD patients, and to what degree that elevation influences secretion of C-reactive protein (CRP), in addition to its
association with other acute phase proteins and kidney function tests .
Method : A total of 75 individuals were included in the present study, 50 individuals were treated with HD compared to 25 healthy volu

Background:Seventy eight patients with beta - thalassemia major were Collected randomly from the thalassemia center in Ibn-Al-Baldy Hospital (all of them were transfusion dependent),
together with fifty six age and sex matched healthy children were collected as a control.
Aim of the study: To determine the incidence of thromboembolism among them and to evaluate the precipitating factors.
Patients and Methods: History was taken and physical examination was done . EDTA Anticoagulated blood samples were taken prior to the next transfusion , platelet parameters were
estimated for both groups using the MS – 9 coulter counter.
Results: Thromboembolic events was detected in five patients (6.41%).The main site was

Background: Asthma is an allergic disease characterized by airway obstruction as a result of cellular accumulation due to the liberation of certain mediators. Among those mediators are the cytokines such as IL-5. 
Patients & Methods: Interleukin-5 concentration has been estimated in 94 sera samples of Asthmatic patients in comparison with 41 non-asthmatic bronchitis as patient controls in addition to 30 apparent healthy control group using ELISA method.
Results & Conclusions: There is highly significant elevation of IL-5 in the asthmatic cases in comparison with healthy controls (P< 0.001). We conclude that this cytokine may play the major
role in asthmatic attack & it may be a good m

ackground :Polyphenolic compounds are groups of naturally occurring compounds in different plants. They are promising product to protect, and prevent leukemia and many types of cancer by different mechanisms.
Objectives: The present study designed to study the effect of polyphenolic compounds [Ellagic acid (EA), Tannic acid (TA) and Caffiec acid (CA)] on GOT,GPT activities and total protein TP concentration in all types of leukemia [acute myeloblastic leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myeloblasti leukemia (CML) and chronic lymphoblastic leukemia (CLL)],in addition to compare the potency of these compounds among each other.
Patients and Methods: Blood samples were collected from a h

Background: Hydatid disease is a serious infection of man caused by larval stage (hydatid) of the small dog tapeworm. Serological tests are important in the diagnosis of hydatid
disease.
Objectives: The study was carried out to detect the rate of seropositivity of hydatid cysts in Kirkuk and Tikrit cities.
Materials and Methods: The retrospective hospital based and seroepidemiological studies were carried out in Kirkuk and Tikrit cities, during the period from beginning of January
2000 until the end of October 2003. The hospital based study included 125-hydatid cyst operations in hospitals of Kirkuk (82) and Tikrit (43). The serological tests used for
detection of hydatid cysts antibody were latex agglu

backgrund:

Background: Upper air way obstruction secondary to chronically inflamed adenoid and / or tonsil is a common problem, in the presence of recurrent infection; tonsillectomy and or adenoidectomy are the most common surgery applied among pediatric population.
Objective: The aim of this study was to assess the type of bacteria encountered with- in the core of the adenoid tissue at time of operation.
Subject and Methods: During a period from Feb.2005 to May 2005, twenty two adenoid samples were removed by surgery ,and cross sectioned and sent for culture and sensitivity, at the department of ENT in Al-jerahat hospital for surgical specialties , most of the patients were under 10 year’s
old.
Results: This

الخلفية: إن عملية استئصال المرارة (كيس الصفراء) بالناظور أصبحت العملية الشائعة لعلاج أمراض المرارة, لذلك معرفة صعوبة العملية قبل إجرائها يساعد الجراح في تقليل الخطورة أثناء العملية وتحويلها إلى عملية فتح بطن.

الهدف: تقييم تأثير سمك جدار المرارة على عملية رفع المرارة بالناظور وعلاقته بالصعوبات أثناء أو بعد العملية.

الطرق والمرضى: در

خلفية البحث: سرطان الثدي هو مرض غير متجانسة إلى حد كبير على الصعيد العالمي. وتلعب العناصر النزرة مثل النحاس والخارصين دورا في العديد من التفاعلات الكيموحيوية كمصدر جزئي، يحدث تغيير في عملية الأيض في أمراض الأورام وخاصة سرطان الثدي والذي يحتل المرتبة الاولى من سرطانات الإناث

الهدف من البحث: الهدف من هذه الدراسة هو دراسة تأثير مؤشر كتلة الجسم وبعض العناصر النز

الخلفية:هناك القليل من المعلومات حول المخاطر المحتمله للجسيمات متناهية الصغر على صحة الإنسان، لا سيما الهرمونات الجنسية.

 الأهداف: تهدف هذه الدراسة إلى معرفة أثر دقائق الذهب النانوية السمية المحتملة على مستويات الهرمونات الجنسية التستوستيرون (T) واستراديول (E2) في امصال دم  البشر الذكور.

المرضى والطرق: شارك 25 رجلا متطوعا بصحة جيدة تراوحت أعمارهم ب

Background: The healing of a sutured tendon in the hand usually occur with an unwanted amount of scarring that defeat good results. Many variables has been studied over many decades; timing of repair M’as a matter of debate. Zone II is the area where those variables mostly affect the results of treatment.
Objective: To study and evaluate the results of early or delayed repair under the effects of our local variables.
Method: Prospective study of 85 patients, which had flexor tendon repair at zone II by primary repair, delayed primary repair and tendon graft.
Results: Results showed a primary repair ended with better functional results than those with delayed repair and than those with tendon graft. Excellent & good results

المرض في منع التخلف العقلي، ولكن هناك بعض الأمراض الاستقلابية الايضية الخطيرة الأخرى  التي تعطي وتتشارك مع مرض الفنيل كيتون يوريا في الاعراض المرضية كذلك.

الأهداف: هدف هذه الدراسه هو معرفة معدل انتشارمرض فنيل كيتون يوريا وغيرها من الامراض الوراثية الاستقلابية الاخرى التي تصيب الاطفال المرضى​​ ، واللذين لديهم بعض الملامح السريرية التي توحي بمرض فنيل كيتون يوريا ،

Background: Disinfection of denture and soft denture liners became among the priorities for cross contamination control as well as patient's health. All the trials aimed to have maximum infection control with minimal adverse changes in the materials properties.
Materials and methods: Discs of 30x2mm were made from Coe Super Soft and Coe Soft denture liners. Every 5 specimens were immersed separately and daily in CHX, Sodium hypochlorite and chlorine dioxide, control group specimens were immersed in the distilled water. Hardness property of the experimental and control groups was evaluated by using Shore A durometer after 1, 7, 30 days. 
Results: Statistical analysis indicated non significant difference

الخلاصة : الخلفيه   التهاب القصيبات هو المرض الاكثر شيوعا للجهاز التنفسي السفلي خلال السنه الاولى من العمر.وهوعادة يحدث بسبب الفيروس المخلوي التنفسي. العلاج عادة ساند لذلك علم الاوبئه والنتائج السريريه والمختبريه والاشعه ربما تسهل التشخيص المبكر والعلاج لحالات التهاب القصيبات .

الهدف : الهدف من دراستنا هي لتقييم الصفات السريريه والنتائج المختبريه للاطفال الراقدين في المستشفى ن

الخلاصة: مرض حساسية الحنطة مرض التهاب المناعة الذاتية في الأمعاء الدقيقة بسبب تناول الغلوتين، وهو مكون من بروتين القمح، في الأشخاص الذين لديهم استعداد وراثي. اختبارات مصلية عن الأجسام المضادة ضد  الاندوميسيم .الرتيكولين والغليادين  لتحديد المرضى الذين يعانون من هذا المرض. حيث ان التشخيص والعلاج المبكر للمرض يمنع العواقب الوخيمة لسوء الامتصاص، مثل هشاشة العظام وفقر الدم.

الخلفية: يعتبر سرطان القولون ذو انتشار كثير في مناطق شمال اوربا, واميركا الشمالية وبريطانيا العظمى ولكن بنسب قليلة في افريقيا واسيا واميركا الجنوبية. هنالك الكثير من المعلمات المناعية التي تتفاعل مع انسجة القولون, فان كثير من سرطان القلون والمستقيم يتفاعل مع (mucin), كذلك يتفاعل سرطان القولون والمستقيم مع (cytokeratins) , وايضا مع CARCINOEMBRYONIC ANTIGEN (CEA).

وهناك الكثير من المعلمات الخر

Background: In breast carcinoma, amplification &/or over-expression of HER-2/neu has been associated with a group of unfavorable prognostic factors. The Food & Drug Administration Agency approved Trastuzumab (Herceptin) for the therapy of metastatic breast cancer but only in patients with amplification &/or over-expression of this gene. Because of these advances, evaluation of HER-2/neu status in breast cancer specimens is of vital importance.
Patients and methods: thirty eight females with breast carcinoma were included in this study. All histologic sections were stained routinely with the hematoxylin and eosin stains and
immunohistochemically for HER2/neu. All cancers were graded and subcatego

Background: Transitional cell carcinomas (TCC) of the bladder are a major health problem. Recently, some studies link high risk Human papilloma viruses' type 16 and type 18 with bladder carcinoma.
Materials and methods: Fifty formalin fixed, paraffin embedded tissues with TCC of the bladder from Specialized Surgical Hospital in Baghdad were included in this study. In addition, ten
apparently normal bladder autopsies were collected from the Forensic Medicine Institute Archives and used as control group. Tissue blocks were sectioned and sticked on charged slides and used for the detection of HPV-16 and HPV-18.
Results: The expression of HPV-16 and HPV-18 DNA signals in TCC of the bladder tissues in the&nbs

Background: Birth trauma is defined as injury to neonates resulting from mechanical forces (such as compression or traction) during the process of birth. Birth injury is used to denote avoidable and unavoidable mechanical and hypoxic- ischemic injury incurred by neonates during labor and delivery. Maternal, labor and infant factors can predispose to birth traumas. Many types of birth traumas can be found including intra and extra cranial, spinal, peripheral nerves, fractures and visceral.
Patients and methods: A cross sectional study was done on 200 babies (100 babies for the study group and 100 babies for the control group), admitted to special care baby unit of Baghdad Teaching Hospital, during the peri

خلفية Idebenone هو دواء يتم استقلابه على نطاق واسع مع ضعف ذوبانه في الماء ويستخدم لعلاج الاعتلال العصبي البصري الوراثي لليبر. الهدف تهدف هذه الدراسة إلى تحضير مستحلب الإيدبينون النانوي كجل أنفي يعتمد على البولوكسامير للتغلب على المعدل الكبير للاستقلاب الكبدي من أجل توافر حيوي أفضل وتقليل التأثير المرضي النسيجي على الغشاء المخاطي للأنف. 

الطرق: استندت استراتيجية العمل

إضافةادوية التخدير المستنشقه امر ضروري. ولكن لا يزال هناك شكوى من أطباء التوليد بشأن تأثير الهالوثين على استرخاء عضلات الرحم ما يؤدي الى زيادة النزف اثناء العمليه.حديثا دخل عقار الايزوفلوران الى العراق.

الهدف: الهدف من هذه الدراسة هو تقييم ومقارنة تأثير الهالوثان والأيزوفلوران على تقلص العضلات الرحمية اثناء العمليه القيصرية.

المرضى والطريقة: