الخلفية: متلازمة تكيس المبايض (Polycystic ovary syndrome ) عبارة عن اضطراب هرموني شائع في النساء في سن الإنجاب مع مظاهر أولية للعقم ،وخلل في الحيض ,و ارتفاع مفرط في هرمون الاندروجين ( زيادة نمو الشعر ،وظهور حب الشباب, وزيادة الهرمون الذكري الاندروجين ). اديبونكتين (Adiponectin) هو اديبوكين الأكثر وفرة وله دور مهم حيث يؤثر على حساسية الانسولين، ومضاد لتصلب الشرايين، ومضاد للالتهابات .
Background: Neonatal screening for congenital hypothyroidism (CH) is an essential preventive public health program for early identification of disorders that can lead to potentially catastrophic health problems
Objectives: This is a pilot study conducted to determine the incidence of CH among infants born in two major maternity hospitals in Baghdad City and to build a model for nationwide screening program.
Methods: A prospective study on screening of all newborns was conducted in two major maternity hospitals in Baghdad, from 01.12.2001 - 31.12.2002. A total of 6949 neonates were screened for CH, cord blood samples were examined for serum TSH levels by immunoflourecent method (ELIZA) and reexamined for T4 using a cutoff&
... Show Moreخلفية البحث: استرواح الجلد هو من الأسباب الشائعة للقدوم الى ردهة الطوارئ. ولكن وجود استرواح الجلد في منطقة الرأس والرقبة نتيجة تداخل جراحي متعلق بالأسنان هو ليس عرض شائع. ووجود استرواح المنصف هو نادر جدا.
تقرير الحالة
دخلت الى ردهة الطوارئ سيده شابه تعاني من الم في الصدر وقد وجد انها تعاني من استرواح المنصف بعد قدومها من عيادة طب بالأسنان حيث قامت بعملية قلع لاحد أسنان العقل.
الخلاصة
ا
... Show Moreboth strongly associated with vascular and metabolic complications. Endothelin-1 is a potent vasoconstrictor that plays a key role in vascular tone regulation and endothelial function.
Objective: To evaluate serum Endothelin-1 levels, lipid profile parameters (total cholesterol, LDL-C, VLDL-C, HDL-C, triglycerides), and HbA1c in patients with type 2 diabetes and essential hypertension compared with healthy controls, in order to assess their association with vascular injury and metabolic risk.
Methods: A case-control study was conducted in the Department of Biochemistry, College of Medicine, University of Baghdad. Between November 2024 and February 2025, a sample of patients were recruited f
... Show MoreBackground: Many characteristics between benign and malignant prostatic tumor which considered similar that make the diagnosis defaults in spacemen of the tumor. The immunohistochemical procedure can improves conventional tumor morphology by identifying lineage- and tumor-associated proteins or markers, facilitating confirmation of prostate origin and distinguish between benign and malignancy tumors.
Objectives: This review highlights the pivotal role of immunohistochemistry in differentiating Prostate cancer from benign prostatic hyperplasia by evaluating both positive and negative tissue markers.
Methods: A narrative review was conducted using methodological features to evalu
Background: One of the top three causes of death and morbidity is cardiovascular disease Myocardial infarction is a clinical illness defined by quickly growing severe myocardial ischemia. It is the most frequent health problem in the world and the main cause of mortality.
Objectives: The study aims to assess the dietary pattern of food intake frequency for patients with post- myocardial infarction.
Patients & Methods: The quasi-experimental design has been carried out to determine the impact of the Dietary Approaches to Stop Hypertension system on patients with post-myocardial infarction, in the Al-Diwaniyah Teaching Hospital's cardiac outpatient clinic
... Show Moreالتقديم : تشكل الإباضة الحدث المركزي في علم وظائف الأعضاء للمبيض ،وضعف الاباضة هو سبب العقم عند النساء ذات الصلة, وفرضية أن الإباضة في الثدييات هي مماثلة للتفاعلات الالتهابية منذ ان وصفت العديد من الجزيئات المسؤولة عن التسبب في التهاب بما في ذلك سلسلة PGS، leukotrienes والسيتوكينات المختلفة في المبيض.
الأهداف: تم تصميم هذه الدراسة للمقارنة بين الآثا
... Show MoreVascular injury is still common in countries such as Iraq where both military and urban violence are endemic.
This is a report of a thirty eight year old civilian patient who had been inflicted with shrapnel injury during the 3rd. Gulf war, which had caused two different types of vascular injury with minimal evidence of vascular injury with evidence of only two small wounds in the neck and upper chest at the time of injury but presented few months later with a pulsatile neck mass and palpable thrill across the right supraclavicular area and upper chest.
Preoperative investigations were done including Doppler study and angiography which confirmed the presence of right common carotid artery aneurysm and
المقدمه:المستقبل شبيه التول-2( TLR-2) يلعب دوراً هاما في بايلوجية الاورام, بواسطة تفعيل وتعزيز انتشار الخلايا السرطانية ومقاومة موت الخلايا المبرمج وايضا تعزيز غزو الخلايا السرطانية وانتشارها.
كما ان المستقبل شبيه التول-2 واسع الانتشار على سطح الخلايا السرطانية ويشارك في بدء وتطور السرطان, فانه قد يعتبر بالتالي كهدف مهم وله تاثير مهتبر في علاج سرطان الثدي.
... Show MoreBackground:
خلفيه البحث: ان ورم غشاء الجنب الخبيث هو ورم غير شائع ينشأ من خلايا الظهارية من غشاء الجنب. من اهم اسباب المرض هو التعرض لألياف المعادن مثل الأسبستوس. ان المفراس الحلزوني يلعب دورا هاما في وصف وتشخيص وتحديد مراحل انتشارالمرض .
اهداف البحث: لتحديد قيمة المفراس الحلزوني في وصف المرض وأثره على التشخيص، وتحديد مراحل المرض، وربط نتائج المفراس مع أنواع
... Show Moreالخلفية: اظهر أبوي طفل التوحد تعاملهم الايجابي على الرغم من إعاقة الطفل ،ولديهم القدرة على مقاومة المشقة والعودة من المصيبة بأكثر قوة وان الآباء استطاعوا التغلب على التحدي المستمر باستخدام مرونتهم للتكيف تجاه المحنة.
الأهداف: تهدف الدراسة إلى تحديد مرونة الأبوين لطفل التوحد وإيجاد العلاقة بين مرونة الأبوين وبعض المتغيرات الديموغرافية العائدة لطف
... Show Moreخلفية البحث: امراض ارتفاع البروتينات الدهنية ( HLP) تقسم الى اولي وثانوي,ارتفاع البروتينات الدهنية الاولي يحدث نتيجة لاسباب وراثية,ارتفاع البروتينات الدهنية الثانوي يحدث نتيجة لاسباب او امراض اخرى مثل مرض السكري2 تقود لاحداث تغييرات في نسب الدهون والبروتينات الدهنية في الدم.
اهداف البحث: قياس الفروقات في مستويات تراكيز هرمون الكريلين بين الرجال الاص
... Show MoreBackground:
الخلفيه:- بطانة الرحم المهاجرة هو خلل مزمن يصيب الجهاز التناسلي للمرأة ويتصف بوجود وأنتشار غدة وسدى خارج تجويف الرحم حيث يصيب 10% من النساء اللاتي في سن الإنجاب، ويعد هذا المرض أحد أكثر الأمراض تعقيداً وإرباكاً ومن أعراضه المرهقة الم دوري في الحوض مما يجعل حياة المريضة لا تطاق إن تركت الحالة بدون علاج. ويزداد مستوى IL-6 لدى مريضات بطانه الرحم المهاجره.
الطريقه:-&nbs
... Show MoreBackground:
Background: the placement of orthodontic appliances creates a favorable environment for the accumulation of microbiota, therefore this study is to assess
the relationship between removable orthodontic appliance and oral microflora.
Materials and methods: a sample 45 patients who come to orthodontic department at the collage of dentistry/Baghdad university, divided into 3 groups:
group 1 (15) without appliance, group2 (15) with appliance for 2 weeks-2 months, and group 3 (15) with appliance for 2 -4 months, then examine the oral microflora
and compared between the 3 groups.
Results: the result showed eleven types of microorganisms appear in group 3 then followed by seven types in group 2 but only three t
Background: Aluminium (Al) intoxication was recognised as a causal agent in p a t i ent s undergoing haemodialysis and then was linked to Alzheimer's disease. Nevertheless, environmental pollution with Al is mainly v i a drinking water, particularly when acidic rain falls on Al containing soil and bedrock. In addition, aluminium utens i l s are widely used for cooking. Therefore, an increasing concern is emerging for the role of pH in the absorption of aluminium from ingested food.
Materials and methods: The objective of this study was to establish the effect of acidification with1 ml/dL of concentrated acetic acid on the absorption of aluminium from a 5 mM a l u mi n i u m sulphate\ solution taken orally
Background: Osteoporosis (OP) is a prevalent age-related condition that increases the risk of fracture and bone fragility, as result loss of bone mass as well as micro-architectural degradation of the bone, thereby reducing the mass and strength of bone. Human β-defensin (HBD-3) is ananti-inflammatory peptide andcrucial part of the human innate immune system. Giving early therapeutic intervention for OP requires an early diagnosis.
Objectives: To evaluate the serum HBD-3 accuracy of diagnosis in patients with osteoporosis.
Methods: The study was conducted in the National Joint Center at Yarmouk Teaching Hospital in Baghdad during September - Octobe
... Show Moreالخلفية : الداء الزلاقي هو مرض مزمن، يحدد مناعيا من شكل الأعتلال المعوي الذي يؤثر في الأمعاء الدقيقة عند الأطفال والبالغين ذوالميول الوراثي . و تظهر بشكل سريع عند ابتلاع الأطعمة التي تحتوي على الغلوتين. ويشار أيضا إلى أنه ذرب الاضطرابات الهضمية والحساسية من الغلوتين في الأمعاء أو غير ذرب الاستوائية.CD69 هو مستضد لمفاوي مفعل الذي ظهوره السريع يجعله مناسبا للكشف عن تنشيط خلايا T و التحل
... Show Moreالمقدمه : ضمور القنوات الصفراويه الولادي هو من الحالات النادره نسبيا والتي تتسبب بحدوث يرقان انسدادي ولاسباب غير معروفه ولكنها تحدث نتيجة تليفات وانكماش القنوات الصفراويه بمستويات مختلفه .هذا الاعتلال يؤدي الى الوفاة خلال عامين ان لم يعالج جراحيا".
الهدف: الغرض من هذه الدراسة هو لتحليل ومناقشة العوامل ا
... Show MoreBackground: depressed mood and anxiety are common symptoms in hospitalized cancer patients .it is often presumed that anxiety and depression affect the occurrence and experience of physical symptoms . the researcher was aimed to assess the level of depression among cancer patients and the chemotherapy side effects and to find out the significant difference between depression level regarding these side effects.
Patients and methods: A descriptive analytical study was conducted on a purposive sample of 50 cancer patients from both sexes who were admitted to Radiation and Neuclur Medicine Hospital in Baghdad for the purpose of giving chemotherapy for the period from April 4th to June 20th , 2008. A structure
الخلفية : سرطان الدم النقياني الحاد عند البالغين يعتبر من الأمراض التي لا يعمر فيها المريض طويلا وان نسبة الشفاء لمدة خمس سنوات هي حوالي 30%.
الغرض من البحث : دراسة خصائص المرضى المصابين المراجعين الى مستشفى بغداد التعليمي واستجابتهم للعلاج ونسبة المرضى الذي يتعافون لمدة خمس سنوات.
طريقة اجراء البحث : تم ادخال 67 مريضاً الى الطابق الساب
... Show MoreBackground: Dysentery is an important cause of morbidity and mortality associated with diarrhea. About 10% of all diarrheal episodes in children less than 5 years are dysenteric, but these cause about 15% of all deaths attributed to diarrhea.
Objective : To demonstrate the most common pathogens causing bloody diarrhea in children between 2 months and 5 years old, to describe some of the associated factors accompanying bloody diarrhea and to highlight the most important clinical features.
Patients and methods: A descriptive study of 82 children, between the age of 2 months to 5 years with bloody diarrhea, who were admitted to the Children Welfare Teaching Hospital/ Medical City/Baghdad during the period betw
Background: a rapid and accurate identification of Methicillim-Resistant Staphylococci (MRS) is of a particular clinical significance because they have cross-resistance to other antibiotics with high ability to be transmitted among hospitalized patients known as epidemic MRS.
Objectives: the detection of MRS and the susceptibility of isolates to antimicrobial agents, also to determine inducible and constitutive macrolide-lincosamide-streptogramin B (MLSB) resistance mechanisms by pharmacodynamic interpretative reading approaches.
Methods: standard disk diffusion method was performed for 30 Staphylococcus aureus and 10 Staphylococcus epidermidis isolated from wound, burn patients admitted to Ramadi General Hospital in Ramadi and e
Background: The study was conducted to investigate the association between hyperprolactinaemia and markers of human leukocyte antigen (HLA) system in a sample of Iraqi infertile females, together with the profile anti-nuclear antibodies (ANA).
Objectives: One hundred and seventy five female patients (age range: 20 -40 years) were recruited in this study. They were attending the Institute for Embryo Research and Infertility Treatment (Al-Nahrain University) during the period January 2005 - September 2006.
Results:After clinical and laboratry evaluations, it was found that 100 patients were hyperprolactinaemic, whereas the other 75 patients were euprolactinaemic, therefore, they were considered as a control group. Based on serum le
Background: Human parvovirus B19 (B19V) is the only human pathogenic parvovirus, It is highly erythrotropic and preferentially replicates in erythroid progenitor cells (EPCs). Recently the effects of B19 infection have been well studied in children with acute lymphoblastic leukemia (ALL).
Objective: To detect parvovirus B19 among children with ALL.
Methods: A cross sectional study involved forty five patients with ALL (21 patients were newly diagnosed ALL and 24 children who underwent chemotherapy) who were attending department of oncology in Children's Welfare Teaching Hospital in Baghdad Medical City between December 2012 and April 2013, compared to forty five of appare
... Show MoreBackground: management modalities for liver metastasis from primary breast cancer are evolving steadily but systemic chemotherapy remains the mainstay of treatment.
Patients and methods: 30 patients with breast carcinoma and liver metastasis managed at (Baghdad teaching hospital) during the period from Jan. 2005 to Jan. 2007.
Results: 16 patients showed response to chemotherapy. 20% complete response was found and 33% showed partial response 57% went into progressive disease. The duration of response lasted for less than six months in 4 patients and more than six months in two patients.
Conclusion: chemotherapy remains the mainstay of treatment of liver metastasis but new modalities of treatment add much