Background: Inhibitor development and HCV are considered the most serious complications of hemophilia treatment. Many factors may increase the risk of complications which include: type of hemophilia, age of the patient, age of onset, duration of the disease, & number of replacement per month. Patients and methods: A descriptive study included 200 patients less than 20 years of age admitted to the Hemophilia Center in Children Welfare Teaching Hospital , medical city in Baghdad , their data ( ag , sex , disease onset and duration , severity of hemophilia ) were collected over 8 months period from 1st January to 31st August 2006. Mixing tests and serology tests for HCV and HBV were performed for all patien

الخلفية: التهاب المفاصل الرَثَيَانِي أو الداء الرثياني أو الالتهاب المفصلي الروماتويدي هو مرض مزمن، من الأمراض الانضدادية التي تؤدي بالجهاز المناعي لمهاجمة المفاصل، مسببة التهابات وتدميرًا لها. ومن الممكن أيضًا أن يدمر جهاز المناعة أعضاء أخرى في الجسم مثل الرئتين والجلد. وفي بعض الحالات، يسبب المرض الإعاقة، مؤدية إلى فقدان القدرة على الحركة والإنتاجية. ويتم تشخيص المرض بواسطة تحاليل دم مخبرية م

المقدمة: متلازمة الأيض الغذائي هي مجموعة معقدة من الأضطرابات الأيضية ، والتي تتميز بمستويات عالية من الكلوكوز في الدم ،  وأرتفاع ضغط الدم، والسمنة في منطقة البطن ، وعسر دهون الدم. تؤثر المجموعة عالية الحركة ، وهي عامل نسخ معماري ، على توازن الكلوكوز. لم يتم إجراء دراسات سابقة لفحص ما أذا كان يٌمكن إفرازHMGA1 في البيئة خارج الخلية.

الهدف: تهدف دراسة الحالة والشواهد هذه إلى فحص ما أ

المقدمة: الوشم عبارة عن مادة غريبة تدخل في أدمة الجلد بواسطة وغز أبرة او أي شدة خارجية اخرى فتنتج علامة في الجلد، وتستخدم لغرض الديكور او الجمالية واحيانا تكون ناتجة عن حادثة طريق واحيانا أخرى نقوم بعمل الوشم لأسباب علاجية مثل تحديد الأماكن المحتاجة الى تسليط علاج أشعاعي.

هنالك طرق عدة لأزالة الوشم و واحدة من هذه الطرق هو ازالة الوشم باستخدام كيو سوج (1064نانو متر،  532

Background: The breast function as a secretory gland during pregnancy and lactation due to the interaction of estrogen, progesterone and other pituitary hormones.

Background: P53 is an important tumor marker in many malignancies, the P53 gene is a tumor suppressor gene that plays a key role in the regulation of the cell cycle.

Background: Congenital adrenal hyperplasia is a family of autosomal recessive disorders of cortisol biosynthesis. Depending on the enzymatic step that is deficient, there may be signs, symptoms, and laboratory findings of mineralocorticoid deficiency or excess; incomplete virilization or premature puberty in affected males; and virilization or sexual infantilism in affected females. The most frequent is 21-hydroxylase enzyme deficiency, accounting for more than 90% of cases.
Objectives: to review cases of congenital adrenal hyperplasia registered in children welfare teaching hospital- medical city- Baghdad.
Patients and method: This study included all patients who were presented and registered in the e

Background: Keloids of the ear present a significant clinical challenge, with surgical excision alone associated with high recurrence rates (45%–100%). Various adjuvant treatments have been explored to improve outcomes, with intra-lesional corticosteroids showing promise.

Objectives: To evaluate the effectiveness and safety of debulking combined with intralesional injection of triamcinolone acetonide versus debulking alone in treating earlobe and helical keloids.

Methods: This study was conducted at the Department of Dermatology and Venereology, Baghdad Teaching Hospital, from January 2014 to October 2015. Twenty-eight female patients with 67 keloid lesions resulting from

Background: A number of investigators have carried out experimental infections of hydatidosis, using albino mice as an experimental animal model, but there was disagreement on the effect of strain, sex and age of this model.
Materials and Methods: Two hundred and forty mice (120 males and 120 females) were injected intraperitoneally with a single dose of 2000 protoscolices (PSCs) /mouse at four ages (3-4, 7-8, 10 and 20 weeks). Each age group consisted of 60 mice (30 males and 30 females); in which 15 animals of each sex were the treated group, while the other 15 animals were a control group (injected with normal saline). Five animals from each age and sex were sacrificed at one, two and four month po sti

Background: Fenugreek herb is one of the most abundant plants in our country. The dried ripe seeds of this plant are the effective medicinal part the plant.
Aim of the work: The aim of this study is to determine the pharmacological effect of a new chemical substance that has been extracted from crude fenugreek seeds which has a hormonal like action and to assess the safety of this experimental material in order to recommend it in future as a stimulator for ovulation or a contraceptive pill.
Materials and Methods: Sixty uncoupled female rats and mice were enrolled in this study, categorized into groups as mentioned in the text. Prolactin, estradiol and progesterone serum levels where measured for all gr

Background: Fenugreek herb is one of the most abundant plants in our country. The dried ripe seeds of this plant are the effective medicinal part the plant.<br />Aim of the work: The aim of this study is to determine the pharmacological effect of a new chemical substance that has been extracted from crude fenugreek seeds which has a hormonal like action and to assess the safety of this experimental material in order to recommend it in future as a stimulator for ovulation or a contraceptive pill.<br />Materials and Methods: Sixty uncoupled female rats and mice were enrolled in this study, categorized into groups as mentioned in the text. Prolactin, estradiol and progesterone serum levels where measured for all groups. Histolog

Background:

Background: Human cytomegalovirus (HCMV) infection during pregnancy causing serious problems through induction of viral genes that enhance the expression of different cellular factors ending in failure of pregnancy.
Patients and Methods: Paraffin embedded sections of curate samples were obtained from 34 women had spontaneous abortion, and 5 women had elective termination of pregnancy (as control), and then subjected for immunohistochemistry analysis to detect human cytomegalovirus (HCMV) early protein, and in situ hybridization technique to detect nuclear factor-κB (NF- κB) mRNA.
Results: Only nine out of 34 women with spontaneous abortion were positive for HCMV early protein, with a significantly higher expression of NF-κB in H

Background: since the occurrence of transient bacteraemia is fatal following different dental procedures in patients at-risk of bacterial endocarditis, the purpose of this research was to estimate the percentage and nature of bacteraemia following four orthodontic treatment procedures which were: an upper alginate impression, separator placement, band fitting or placement, and arch wire adjustment on a fixed appliance.Materials and methods: the study group consisted of 40 patients (25 females and 15 males) ranging from 17-25 years of age attending Orthodontic Department in the College of Dentistry/Baghdad University, and out patients department from private clinic. The 40 patients were divided into four groups (10 patients each). A cannu

                الخلفية: وفقا للدراسات الحالية فان التغييرات في شخصية الدهون لدى الحوامل هو العامل الرئيسي في احداث مقدمات الارتعاج. صممت الدراسة لمقارنة التغيرات في شخصية الدهون في النساء ذوات الحمل الطبيعي وتلك ذوات تاريخ مرضي بمقدمات الارتعاج المتكررة.

الهدف: لتقيم العلاقة بين تغيرات الدهون الشخصية في الحمل المبكر عند ال

Background: Indeterminate colitis (IC) originally referred to those 10–15% of cases of inflammatory bowel disease (IBD) in which there was difficulty distinguishing between ulcerative colitis (UC) and Crohn’s disease (CD) in the colectomy specimen and histopathology examination. However, IC is increasingly used when a definitive diagnosis of UC or CD cannot be made at colonoscopy examination, colonic biopsies or at colectomy. The diagnostic difficulties may explain the variably reported prevalence of IC. Clinically, most patients with IC evolve to a definite diagnosis of UC or CD on follow up.
Patients and methods: PATIENTS GROUP: Consisted of 80 patients with indeterminate colitis (IC), their ag

Background: β-thalassemia major is a genetic disorder characterized by reduced rate of β-globin chain production. Clinically, β-thalassemia major is a severe, transfusion-dependant disorder; repeated blood transfusion will lead eventually to chronic liver disease.
Patients and Methods: One hundred patients ; 56 males and 44 females who were known cases with β-thalassemia major on regular blood transfusion, aged between 6 months and 18 years, were studied in a private pathology laboratory, between January 2002-January 2006.Blood was drawn to estimate serum glutamic pyruvate transaminase (SGPT) and serum glutamic oxaloacetic transaminase (SGOT) levels.
Results: Sixty-six patients (66%) had elevated S

خلفية البحث: الأشخاص الذين يعانون من اضطراب طيف التوحد لديهم معدل انتشار مرتفع للنوبات الصرعية مقارنة بالأشخاص العامة وفقا لمجموعة كبيرة من الابحاث أيضا تم العثور على مرضى طيف التوحد الذين لا يعانون من نوبات صرعية لديهم معدلات عالية من موجات صرعية. ومع ذلك، لا يزال من غير المعروف كيف ترتبط هذه الموجات الصرعية بين أعراض التوحد.

الأهداف: استخدمت هذه الدراسة تخطيط كهربية الدماغ للتحقيق ف

Background: Epilepsy is one of the most common neurological disorders. People who know less about epilepsy tend to have negative ideas about the disease. KAP of parents on epilepsy is crucial, especially to children below 13, as the child in this stage mostly depends on parents to get the answers to their concerns. Still, the overprotection from their families will create insecurity and reduce their self-esteem when they grow older.

Objectives: To assess the knowledge, attitude, and practice (KAP) and measure their association with sociodemographic characteristics.

Methods: A cross-sectional study involved 107 parents with children who were diagnosed and received treatment

الخلاصة

دواء التلميسارتان الخافض للضغط يستخدم عادة لعلاج ارتفاع ضغط الدم وأمراض الكلى. هو دواء لمستقبلات الأنجيوتنسين النوع الثاني

الخلفية: متلازمة المبيض المتعدد الكيسات (PCOS) هي أحد أمراض الغدد الصماء والأيض السائدة التي تصيب ما يقرب من 15٪ من النساء في سن الإنجاب على مستوى العالم. وهو أحد أكثر أسباب العقم شيوعًا ، ويتميز بالشعرانية وحب الشباب والإباضة المستمرة أو المتقطعة وفرط الأندروجين في الدم. Neuregulin-4 هو هرمون من عائلة بروتين Neuregulin ويعمل بمثابة adipokine. يكون مستواه أعلى لدى النساء المصابات بمتلازمة تكيس المبايض منه لدى النساء

الخلفية: العقدية المقيحة المعروفة أيضًا باسم ""(GAS) هي احدى مسببات الأمراض ذات الأهمية الصحية العامة، حيث تصيب 18.1 مليون شخص في جميع أنحاء العالم وتقتل 500000 شخص كل عام.

الهدف: حددت هذه المراجعة المقالات المنشورة حول عوامل الخطر واستراتيجيات الوقاية والسيطرة لأمراض المكورات العقدية.

المواد والأساليب: تم إجراء بحث منهجي لتحديد الأوراق المنشورة على قواعد البيانات الإلكترون

الخلفية: تعد متلازمة المبيض المتعدد الكيسات من أكثر أمراض الغدد الصماء شيوعًا التي تصيب النساء في سن الإنجاب، حيث يلعب الليفوكارنتين دورًا مهمًا في الإجهاد التأكسدي وإنتاج الطاقة واستقلاب الجلوكوز. يؤثر على مقاومة الأنسولين حيث تم الإبلاغ عن انخفاض مستوى الكارنيتين في البلازما بشكل جيد في النوع الثاني من داء السكري، مما يعني أن الليفوكارنتين قد تقلل من مقاومة الأنسولين الموجودة في مرض المبيض الم

الخلفية: تم تقييم كثافة المعادن في العظام () باستخدام مقياس امتصاص الأشعة السينية ثنائي الطاقة (DEXA). يتم قياس كثافة المعادن بالعظام وفقًا لنتائج فحص DEXA للعمود الفقري والحوض. على الرغم من أنه من المعروف أن مرض السكري () يؤثر على كثافة المعادن بالعظام ، إلا أن المعلومات المتعلقة بهذه العلاقة ليست واضحة بشكل خاص حاليًا.

  الهدف: كان الهدف من الدراسة الحالية هو تقييم آثار داء السكري م

Background: Patients with spinal cord injuries often face unique challenges related to their dietary regimen. Adequate knowledge about dietary regimens is crucial for their overall health, well-being, and management of specific nutritional needs.

Objectives: To evaluate the effectiveness of the instructional intervention in enhancing knowledge about dietary regimens among patients with spinal cord injuries and to compare the knowledge levels between the intervention group and the control group.

Patients and Methods: The study was conducted from 8^th of March 2023 to 15^th of February 2024. Sixty patients at Ibn Al-Kuff Hospital for Spinal Cord Injuries i

Background: Gastric ulcer is a prevalent gastrointestinal disorder caused by environmental factors and a higher intake of non-steroidal anti-inflammatory drugs (NSAIDs).
Objective: To investigate the prophylactic effects of melatonin on the histology, severity of gastric ulcers, and levels of inflammatory and oxidative stress markers (Interleukin-1beta (IL-1β) and Malondialdehyde (MDA)) in a rat model of indomethacin-induced ulcers.
Methods: This study was performed at Al-Mustansiriyah University's Research Center for Cancer and Medical Genetics from November 2023 to May 2024. Fifty healthy male albino rats weighing between 150 - 250 grams were used. After 24 hours of fasting,

Background: Doctors and patients communicating effectively is a very important base in cancer clinics and out-patient, the “Bad” news is any information that drastically alters a patient’s prospect of their life and forthcoming possibilities. It includes facts about diagnosis, recurrence, and treatment failure in clinical oncology settings.

Objective: To assess the attitudes of cancer patients toward receiving bad news of their condition and the relationships of some sociodemographic variables to these attitudes.

Methods: A cross-sectional study was conducted from the 19^th of February to the 1^st of June 2017 at the Oncology Hospital in the Medica

background:

Background:

Background: Among the most prevalent hormonal, reproductive and metabolic issues impacting women is polycystic ovarian syndrome. Also, insulin resistance raises the chance of developing chronic illnesses in women with polycystic ovarian syndrome, including diabetes mellitus, cardiovascular disease, metabolic syndrome, and potentially endometrial and breast malignancies.
Objectives: Measurement of two intestinal hormones (cholecystokinin, peptide YY), luteinising hormone, follicle-stimulating hormone, and Prolactin. Waist and wrist circumference were measured in centimeters
Methods: A sample of polycystic ovarian syndrome women who were referred to the Medical City of Baghdad ho