Background: Rheumatoid arthritis is an inflammatory illness. A complication of Rheumatoid arthritis is mainly linked to the risk of cardiovascular disease. High body weight has been implicated as a perilous risk factor for the development of Rheumatoid arthritis. Neopterin is secreted by monocytes and macrophages and is highly secreted from the coronary plaque. Moreover, high-sensitivity C-reactive protein is a biochemical analysis applied to quantify C-reactive protein with high sensitivity.
Objectives: To evaluate serum Neopterin and high-sensitivity C-reactive protein in patients with rheumatoid arthritis to predict the risk of coronary artery disease. In addition, a correlation between neopterin
Background: The thyroid is a vital endocrine gland that regulates growth, metabolism, and development. Thyroid dysfunction (TD) and diabetes mellitus (DM) are two prevalent endocrine disorders with overlapping pathophysiological features.
Objective: To investigate the potential role of proenkephalin-A (PENK-A) as a diagnostic and predictive biomarker for type 2 diabetes in women with thyroid dysfunction.
Methods: A total of 130 women aged 25–55 years were enrolled in the study, including 100 patients with thyroid disorders and 30 healthy controls. The study was conducted from December 2024 to April 2025 at Al-Kindy Center for Endocrinology and Diabetes in Baghdad. Participant
خلفية البحث:المرضى المستمرين على الغسل الكلوي الدموي هم أكثر عرضة للإصابة بالالتهابات الفايروسية المنقولة دمويا. في السنوات الحديثة تم توثيق انتشار كبير لالتهاب الكبد الفايروسي نمط ج بين مرضى العجز الكلوي ومرضى الغسل الكلوي الدموي المستمر.
الأهداف:لتقييم نسبة وعوامل خطورة التهاب الكبد الفايروسي نمط ج عند مرضى الديلزة الدموية ولتقييم العواقب السريرية لالت
... Show Moreالخلفية: سرطان الثدي هو اكثر الامراض السرطانية شيوعا في العالم والسبب الرئيسي للوفاة بسبب السرطانن بين النساء عبر العالم.
HER2المقدمة: الهدف من الدراسة لمعرفة امكانية السونار في تحديد نتائج الفحص النسيجي لسررطان الثدي وتكهن حالة ال
المرضى والطرق:أجريت هذه الدراسة عن طريق الاختيار الرجعي ل 102مريض شخصوا باصابتهم بمرض سرطان الثدي خضعوا
... Show Moreخلفية عن البحث : ان الغذاء المتناول يعتبر مهما اثناء فترة الحمل ,لان الكميات غير الكافيه للمواد الاساسيه قد يؤثر سلبا في تكون الطفل او صحه الام.بالاضافه الى ذلك فان غذاء الام قد يكون احد الطرق لاختيار جنس الجنين .ان الهدف من هذه الدراسه هو للتحري عن وجود علاقه بين مستوى المعادن في دم الام مع جنس الجنين وصحه الطفل المولود.
الاهداف:لتقييم تاثير الرصاص ,المغنيسي
... Show MoreBackground: Neural tube defects (NTDs) are said to be inherited in a multifactorial fashion, i.e. genetic-environmental interaction. Maternal nutritional deficiencies had long been reported to cause NTDs, especially folate deficiency during early pregnancy. More attention had been paid to the exact mechanism by which this deficiency state causes these defects in the developing embryo. The most significant of all researches was that connecting reduced folate and increased homocysteine level in maternal serum on one hand and the risk of developing a NTD baby on the other hand.
Objectives : to determine the significance of homocysteine level in Iraqi mothers who gave birth to babies with NTDs as compare
Background:
B -Natriuretic peptide is a neurohormone normally synthesized in ventricular heart muscle and known to be released in situations when left ventricular wall stress increases, it
has a variety of physiological functions on its own, that are thought to be compensatory.
Objective:
The aim of this study was to apply B-natriuretic peptide (BNP) as a biomarker and to correlate its levels with the severity of heart failure using certain selected parameters as
indicators of cardiac function.
Patients and Methods
Forty Six (46) patients with provisional diagnosis of heart failure were chosen for this work, thirty six (36) males and ten (10) Females, their age ranged between 33 and 80 Years.
All un
Background: Glucose -6-phosphate (G6PD) deficiency seems to be a major cause of neonatal hyperbilirubinaemia. This study was carried out to determine the prevalence of G6PD deficiency among icteric neonates in western Iraq and to evaluate its association with hemolysis in neonatal jaundice.
Patients and Methods: All icteric neonates admitted to Al-Ramadi Maternity and Paediatrics hospital, Al-Anbar governorat, for the period from 1st Feb. to 1st Dec. 2006 were included in the study. Data collected from case records and includes age, sex, total serum bilirubin hemoglobin level, reticulocyte count, blood group and Rh of the mothers and neonates, direct coomb's test and peripheral smear. G6PD enzyme
... Show MoreBackground: The importance of essential trace elements plays a major role in medicine mainly cardiovascular diseases.
Methods: The study involved 305 patients with either myocardial infarction ( MI ) , angina pectoris ( AP ) or hypertension ( HT ) for evaluation of these trace elements level ( Se & Cr ) as compared with 100 control subjects in Ibin Al Bitar hospital for cardiac surgery between July 2003 and May 2005 by using Atomic Absorption Spectrophotometer ( AAS ) done in the laboratories of ministry of Sciences and Technology in Baghdad.
Result: The total numbers of patients enrolled in this study were 305 patients, Ml contributes to 70 patients, 55 male and 25 female with
Background: Angioplasty and stenting; Percutaneous coronary intervention (PCI) has become important tool of Reascularizing patients with stable angina and Acute ST-Elevation Myocardial Infarction, while their role in Non ST-elevation Acute coronary syndrome is expanding.
Objestives: The aim was to study the outcome of complete and incomplete Revascularization, by PCI, of pts with NSTE-ACS, and the effect of the traditional risk factors and their relation to the number of stents.
Patients and Methods:- After stabilization 115 out of 142 consecutive hospital admissions with Non St-Elevation Acute Coronary Syndrome were revascularized Percutanously.
Re
... Show MoreBackground:
Progesterone hormone is important in the preparation for and in maintaining of pregnancy through different mechanisms but mainly by shifting the balance from Th1 to Th2 mediated
immunity to avoid rejection of the fetus; in this study we tried to find out whether there is a relation between the level of the expression of progesterone and its stimulant HCG hormone and recurrent pregnancy loss (RPL).
Patients and Methods:
Immunohistochemistry technique was performed to detect and determine the expression of progesterone and HCG hormones using paraffin embedded sections of curate samples obtained from 40 women, who where divided into three groups: 24 women with RPL, 10 women with abortion
Background:
There are many circulatory changes that occur during exercise in order to supply the tremendous blood flow required by the muscles during the stimulatory effects on circulation
by the mass sympathetic discharge, the increased arterial pressure and cardiac output. The metabolic effects and the oxidative stress as a result of the work load on cardiac and skeletal
muscles could also show changes.
Objective:
This study was designed to investigate the effects of aging process on the vascular response during exercise and also in the oxidative stress according to age.
Subjects and Methods:
Eight healthy Iraqi subjects were enrolled in this study. Divided into three groups according to a
Background:
Variations in the arterial supply in the human brain are not uncommon. Of particular interest is that of the hippocampus. Knowledge of the vascular anatomy is a key to the
surgical treatment of pathologies in this region.
Objectives:
The aim of the work is a detailed description of the variations and contribution of the anterior choroidal artery and the branches of the posterior cerebral artery to the supply of
the hippocampus and comparing the results with previous studies.
Materials and Methods:
Formalin-fixed brains from 15 adult cadavers (30 hemispheres) were examined using a magnifying lens. The hippocampus is identified, and the arteries that are in the vicinity to
hippocampus were
Background: - Genetic Factors have a major role in the development of bladder cancer.
Objectives: - This study was carried out to shed a light on the possible association of HLA class II antigens and BC patients and to correlate this finding with the family
history.
Patients and Methodes :- Lymphocytotxicity assay had been used to assess HLAtyping of 65 BC patients and 50 healthy controls.
Results:- comparison between BC patients and healthy controls showed several antigens deviations in their frequencies. HLA-DR1, HLA-DQ1 and HLA-DQ3 antigens
were observed with increased frequencies in patients group with significant differences (P=0.000, 0.000 and 0.017 respectively). Moreover there was decrease
Background:
Hepatitis C Virus is the main causative agent of hepatitis among blood transfused patients, in which most chronic cases result in liver carcinoma.
Materials & Methods:
Enzyme-Linked Immunosorbent Assay for HCV, FNF- and IL-12p40 estimation with Recombinant Immunoblotting Assay (RIBA) as a confirmatory test for HCV, have been
applied for HCV detection in 80 HCV patients' samples in comparison with 30 samples for apparently healthy control, while viral load has been estimated using Branched-DNA (b-
DNA) technique for 32 randomly selected positive cases for HCV. Liver function test has been applied for patients' sera in comparison with control.
Results & Conclusions:
This study re
Back ground: Viruses may be involved in the pathogenesis of Type 1 Diabetes Mellitus (T1DM), either through direct β-cell infection or as triggers of
autoimmunity.
Objective: To investigate the presence of specific anti- viral IgG antibodies for Coxsackie virus type B (CVB5), Poliovirus, and Adenovirus which proposed to be
involved in the etiology of T1DM.
Subjects & methods: A total of 60 Iraqi T1DM children were included in the presents study. They were new onset of the disease (diagnosis was from one week up
to five months). For the purpose of comparisons, 50 apparently healthy control subjects were selected. Serum IgG against Coxsackie virus type B5, Adenovirus type
3, 4, and 7, and Poliovac
Background: There is a need for a periodic review of acute bacterial meningitis (ABM) since the pathogens responsible for infection vary with time, geography and patient's age. This study was carried out to describe the epidemiology of different types of meningitis and variables affecting the outcome (improvement, complication and death).
Patients and Methods: All the cases of meningitis diagnosed and treated at Ibn- Al-Khateeb Teaching Hospital for the period Jan. 1993 to Dec. 1998 were included in this study. The collected data were age, sex, occupation, date of admission, date of discharge, type of meningitis and outcome of the disease.
Results: Out of the total cases, 73.3% were ABM. High rate of A
Background: Ministry of Health, since its establishment, adopted the policy of central financing system and free medical services in all health facilities. The sanction and the decline in per capita spending affect the health financing system, thus in 1997 a new financing policy was adopted as pilot in seven specialized hospital called “self–finance” system in which the cost of care was shifted to the patients, i.e. the funds obtained came from user charges at the health facilities. This system was extended (with some modifications) to all hospitals in 1999 and PHC centers in 2001 and implemented until 2003 when it was discontinued.
Materials and Methods: During the second half of 2004, a review of
Background: The level of parent education has an important role in making decision about their children oral hygiene.<br />Material and methods: A cross sectional descriptive study was conducted in Baghdad city, the total sample include 569 preschool children (318 males and 251females) aged 5-years, they were randomly selected from different kindergartens. For measuring oral cleanliness gingival condition and dental stain, Plaque index by Silness and Lِe gingival index by Lِe and Silness and stain index by Leung were used respectively.<br />Results: Results showed that the mean plaque index was (0.68 ± 0.018) results reveal a high prevalence of gingival inflammation (77%)with mild type was found to be the predominant, as m
... Show MoreBackground: the management of gun shoot wounds of the spinal cords (G sws) is still a debate whether to interfere surgically or not, the interferance is usually laminectomy & Bullet
extraction.
Objectives: A comparative prospective study between surgical & non-surgical management of G sws.
Methods: A case series study of (52) patients with G sws were managed by the neurosurgical unit in Ibn Sinna hospital in Mosul. 27 patients surgery was done, 25 patients non-surgical
management. A comparative study done according to the surgical outcome, improvement, mortality between the 2 groups in a mean follow up period of 4.5 months.
Results: The mean age was 35, (9-50 years) , mean follow up 4.5 mon
Background: Venous thromboembolic (VTE) disease with i t ' s h i g h morbidity and mo r t a l i t y is currently one of the most serious postoperative complication, (DVT) can lead to
fatal pulmonary embolism (PE). or the development of post thrombotic syndrome.
Patients and methods: This is a prospective study which was carried on 85 patients had s i n g l e lower l i m b open fracture with no other major i n j u r i e s in other sites of body
(with the exception of superficial wounds or b r u i s e s ) .They were d i v i d e d i n t o groups according to age, gender, weight, type of fracture, methods of immobilization, duration of
h o s p i t a l i z a t i o n , duration of operation. All the patients includin
Background: Fibromyalgia syndrome is a common rheumatological syndrome with multiple systemic manifestations & associated with many diseases. The aim of the study is to assess the
possible association between fibromyalgia syndrome (FMS) & chronic obstructive pulmonary disease (COPD), and to correlate this association with patient's age, age group, sex, marital status, duration of the disease, & its severity.
Patients and Methods: Fifty patients with COPD & 50 healthy controls were included in this study. Full history was taken & complete physical examination was done for all patients in both groups. Disease characteristics [age, age group, sex, marital status, duration of the disease, &a
Background: Brain abscess is collection of pus in the brain parrynchima surrounded by a true capsule. Usually diagnosed by CT & MRI, & treated surgically by drainage by burr hole, or excision.
Objective: evaluate our work with brain abscess.
Patient& method: 74 Patients collected in the specialized surgical hospital neuro-surgical department, from Jan. 1995 till Jan. 2005 treated surgically, all cases fully evaluated clinically & radiologically & then evaluation of the surgical procedure.
Results: there is a slight male predominance & prevalence more in the 1st 2decades of life mostly in children with cong. heart disease, headache was the most common presenting feature, with other signs of infection diagn
الخلاصة: الخلفية:نزيف ما بعد الولادة هو أحد أهم أسباب الاعتلال والوفيات بين الأمهات. هناك بعض الطرق الفعالة والفسيولوجية لمعالجة المرحلة الثالثة من الولادة. وتهدف هذه الدراسة إلى تقييم ومقارنة فعالية حقن عقار الأوكسيتوسين داخل وريد الحبل السري والصرف الحبل المشيمي في معالجة المرحلة الثالثة من الولادة.
هدف الدراسة: الهدف من الدراسة هو تقييم فعالية زرق عقار الأوكسيتوس
... Show Moreالمقدمة: سرطان الثدي هو الورم الخبيث الأكثر شيوعا بين النساء في جميع أنحاء العالم , بل هو أيضا السبب الرئيسي للوفيات المرتبطة بالسرطان في الإناث. عقار التاموكسفين هو العلاج الهرموني الشائع للمرضى الذين يعانون من سرطان الثدي. حيث يعمل بانتقائية عالية عن طريق منع تأثير هرمون الأستروجين بواسطة منع ايصال الأستروجين للمستقبلات الضرورية لفعاليته في اجزاء
... Show MoreBackground: Glomerular injury can be caused by immunologic, infectious, toxic, metabolic and heamodynamic factors. The glomerular response to injury determines the pathology, which can be observed in renal biopsy. The purpose of this study was to analyze different histopathological subtypes of primary and secondary glomerular diseases in children.
Patients and methods: A retrospective study was done on 100 renal biopsy cases in children welfare teaching hospital between December 2003 and December 2007. Ultrasonically guided
biopsies were taken and only light microscopy was used to examine the specimens.
Results: The study group included 100 cases with renal diseases, 83 (83%) cases of which having primar
Background: CA19-9 is among a group of mucin glycoprotein sialosyl lewis antigen (SLA) having come to be recognized as a circulating cancer associated antigen for gastrointestinal cancer. Basic research into cancer causation will be a powerful determinant of intervention in the transformation process reinforcing the need for developing effective molecular tumor biomarkers for early detection of malignant evolution in tissues of organs i.e. stomach, colon and rectum. In this study, we make a comparsion between the levels of CA19-9 in sera and tissues of patients with these diseases to see if their levels are proportional and if it is a tumor marker that affect with malignant cells in tissues of these org
... Show MoreBackground: The umbilicus, before and shortly after sloughing of the cord, can be a source of infection or toxicity. The infection can be severe, such as septicaemia
or tetanus neonatorum.
Method: Mothers of 200 neonates seen at the Children Welfare Hospital, outpatient department, Baghdad, and at Al-Takia health centre, Baquba, were interviewed about the separation of the umbilical stump and the care of the umbilicus after delivery at home or hospital, in the period, January to July 2003, excluding March and April, the time of active military invasion of the country.
Results: For occlusion of the cord a plastic clamp was used in all hospital deliveries, and 80% of home deliveries. A cotton thread or a s
Background: Inhibitor development and HCV are considered the most serious complications of hemophilia treatment. Many factors may increase the risk of complications which include: type of hemophilia, age of the patient, age of onset, duration of the disease, & number of replacement per month. Patients and methods: A descriptive study included 200 patients less than 20 years of age admitted to the Hemophilia Center in Children Welfare Teaching Hospital , medical city in Baghdad , their data ( ag , sex , disease onset and duration , severity of hemophilia ) were collected over 8 months period from 1st January to 31st August 2006. Mixing tests and serology tests for HCV and HBV were performed for all patien
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