الخلفيةالدراسة: يرتبط استخدام وسائل منع الحمل عن طريق الفم مع زيادة نسبة الدهون في الدم والتمثيل الغذائي للكربوهيدرات وكذلك عوامل التخثر بما في ذلك زيادة مستويات العامل السابع في البلازما، عامل X، الفيبرينوجين و D-dimer
الهدف من الدراسة: لتقييم تأثير حبوب منع الحمل عن طريق الفم على عوامل التخثروهي وقت البروثرومبين، تنشيط وقت ثرومبوبلاستين الجزئي، ومستوى ال
... Show Moreالمقدمة :- لاحظ في مرضى العجز الكلوي المزمن زيادة حالات النزف . بصورة عامة حالة النزف تكون موازية الى شدة تركيز النتروجين في الدم .الفسلجة المرضية لحالة النزف معقدة وفيها نلاحظ خلل في وظائف الصفائح الدموية والتخثر اضافة الى قلة الاقراص الدموية التي تشاهد في بعض المرضى.
الهدف من الدراسة :- لتحديد تغيرات في بعض مؤشرات توقف نزف الدم عند مرضى عجز الكلى المزمن, وت
... Show Moreالخلفية:- يعتبر داء السكري من اكثر الامراض شيوعا ومسبب رئيسي للمضاعفات من بين باقي الامراض غير الانتنقالية ويعتبر من اسباب ارتفاع كلفه العلاج خصوصا والنظام الصحي عموما. وتم التركيز بالخصوص على ثقافة المريض بمرضه بصوره خاصه كونها عامل محدد في تقدم المرض لديه.
الاهداف:- تهدف الدراسة الى قياس وتقييم الثقافة الصحية لمرضى السكري من مراجعي مراكز الرعاية الصحية الا
... Show Moreالمقدمه: مرض الأكياس المائية يتسبب عن الأصابة بدودة الكلب( المشوكة الحبيبية)وله أهمية من الناحية كونها تسبب عدوى حيوانية مشتركة مما تؤثر على الناحية الأقتصادية والصحة العامة يشكل رئيسي وهذا ما يهدد مناطق محددة من الشرق الآوسط وهذه المناطق الموبؤة بدودة المشوكات الحبيبية "ولابد من وضع استراتيجية للوقاية والتحكم .مما يتطلب وصف المشوكة الحبيبية في جميع الدراسات الجزيئية للتحري عن ال
... Show MoreBackground: Between 0.3% and 2% of pregnant women experience hyperemesis gravidarum. It is recognized by persistent and unexplained vomiting and dehydration, and the diagnosis is confirmed by significant loss of weight, usually more than 5% of the pre-pregnancy weight. Tumor necrosis factor-α is a multipotent cytokine that affects a vast array of cells. It is now well accepted that the tumor necrosis factor-α is crucial in the very early stages of pregnancy.
Objectives: To assess the relationship between the tumor necrosis factor-α and hyperemesis gravidarum.
Methods: This case-control study was carried out at the Baghdad Teaching Hospital, Obstetrics and Gynecology Depa
... Show MoreBackground: Infertility is the inability to conceive after one year of unprotected intercourse, with male factors accounting for about 50% of cases. Anti-Müllerian hormone (AMH), a glycoprotein belonging to the Transforming growth factor beta family, is secreted from Sertoli cells and plays a key role in male sexual differentiation.
Objectives: To examine the potential role of Anti-Müllerian Hormone in differentiating the subtypes of male infertility.
Methods: This case-control study was done at the Infertility Center of Al-Batool Teaching Hospital in Diyala Governorate, Iraq, by the Department of Biochemistry / College of Medicine / University of Baghdad between April 2024 a
تمهيد: كان لظهور اجهزة غلق الاوعية الدموية الحديثة والمعتمدة على تقنية الكي الكهربائي ثنائي القطبية تاثير كبير على تطور عمليات الجراحة الناظورية المتقدمة و من بينها عملية استئصال الطحال بالناظور الجراحي والتي تعتبر من العمليات التي اثبتت وجودها بين العمليات الناظورية. في هذه الدراسة يتم الاعتماد كليا على مثل هذه الاجهزة في اجراء العملية من دون استخدام دبابيس او كابسات جر
... Show Moreخلفية: تسارع التنفس الولادي المؤقت TTN)) هو اضطراب شائع في الأطفال حديثي الولادة. ويتميز هذا بتسارع التنفس منذ البداية و في بعض الأحيان مع تراجع الصدر أو الانين وأحيانا زرقة تزول باستعمال الحد الأدنى من الأكسجين (<40٪).
الأهداف: تحديد عوامل الخطر ووصف الخصائص السريرية والعلاج والنتائج النهائية للرضع المصابين بال TTN
. المرضى والطرق:
... Show Moreخلفية البحث: عملية ترقيع غشاء طبلة الاُذن هي عملية إغلاق (إعادة بناء) ثقب غشاء الطبلة بإستعمال مادة ترقيع بواسطة طريقة التغطية التحتية أو التغطية الفوقية. اللفافة الصدغية (تمبورالس فاسيا) هي من اكثر المواد شيوعاً التي تستعمل لهذا الغرض.
هدف الدِراسة : لتقييم الفرق في نتائج عملية ترقيع غشاء طبلة الاُذُن في حالات إلتهاب الاُذُن الوسطى المزمن الفعّال وغ
... Show MoreBackground: Extensively drug-resistant Klebsiella pneumoniae (K. pneumoniae) is a significant problem currently due to the increasing prevalence of this pathogen.
Objectives: To underscore the growing threat of antibiotic-resistant K. pneumoniae by investigating the prevalence of class 1 integrons among selected multidrug-resistant (MDR) clinical isolates, with the goal of emphasizing the need for strengthened surveillance and targeted antimicrobial strategies.
Methods: Seventy-four K. pneumoniae isolates have been identified out of 200 clinical samples from different clinical sources (urine, burns, blood, sputum, wounds). Isolates w
Background: Urinary tract infections are one of the most common bacterial infections, caused mainly by Escherichia coli. Uropathogenic Escherichia coli (UPEC) possess virulence factors that can worsen infections, partly regulated by the BarA/UvrY two-component system, which controls genes associated with adhesion, motility, and biofilm formation through small RNAs and carbon metabolism regulators.
Objectives: To determine the pathogenicity and some genotype features of Escherichia coli from urine specimens collected from young women patients and assess their antibiotic resistance.
Methods: Between September and November 2024, 20
... Show MoreBackground: Breast cancer is a leading malignancy in women, shaped by genetic and environmental factors. Resistin, a potential chemotherapy target, may contribute to chemoresistance when mutated. This study applies computational methods to analyze how single-nucleotide polymorphisms alter resistin’s structure and function, potentially reducing its chemotherapy sensitivity.
Methods: A total of 105 fresh blood samples were collected from patients recruited from the Oncology Teaching Hospital, Medical City, Baghdad, Iraq. between March-2020 and September-2023. Samples were classified into 3 groups of 35 samples each: control, benign and patients. DNA extraction, PCR, Sanger sequencing and computa
... Show MoreBackground: Vitamin D deficiency is a risk factor for neuropsychiatric disorders and autoimmune diseases.
Objectives: This study aimed to investigate the relationship between vitamin D and the pathogenesis of primary hypothyroidism.
Methods: A case-control study was conducted at the Department of Biochemistry, College of Medicine, University of Baghdad, and Endocrinology and Diabetes Clinic. The study involved 81 patients aged 29-62 years, with 24 newly diagnosed hypothyroidism, 33 had established hypothyroidism, and 24 had subclinical hypothyroidism. The control group consisted of 40 healthy individuals aged 29-62 years. The study used the MAGLUMI® 800 analyzer Chemiluminesce
Background: Cell-cycle-regulating proteins, including cyclin-dependent kinase inhibitor 1B p27kip1, have been researched in different malignancies, including thyroid carcinoma, and their association with tumor aggressiveness and recurrence has been examined in many tumors.
Objective: This research aimed to examine the clinicopathological relevance of reduced cyclin-dependent kinase inhibitor 1B p27kip1 expression in papillary thyroid carcinoma and its association with the clinicopathological parameters indicative of papillary thyroid carcinoma aggressiveness.
Methods: Formalin-fixed, paraffin-e
... Show MoreBackground: Axial spondyloarthritis is a chronic inflammatory disorder driven by tumor necrosis factor alpha and the interleukin-23/interleukin-17 pathway. Tumor necrosis factor alpha inhibitors such as infliximab improve outcomes, but responses vary, suggesting genetic influences; vitamin D receptor polymorphisms—particularly BsmI ( rs1544410) may modulate disease activity and therapeutic response.
Objectives: This study aimed to investigate the association between the VDR BsmI polymorphism and disease activity, as well as infliximab treatment response in patients with Axial spondyloarthritis.
Methods: A cross-sectional study was conducted on 150 AxSpA patients (108 males, 42 females) receiv
Background: The thyroid is a vital endocrine gland that regulates growth, metabolism, and development. Thyroid dysfunction (TD) and diabetes mellitus (DM) are two prevalent endocrine disorders with overlapping pathophysiological features.
Objective: To investigate the potential role of proenkephalin-A (PENK-A) as a diagnostic and predictive biomarker for type 2 diabetes in women with thyroid dysfunction.
Methods: A total of 130 women aged 25–55 years were enrolled in the study, including 100 patients with thyroid disorders and 30 healthy controls. The study was conducted from December 2024 to April 2025 at Al-Kindy Center for Endocrinology and Diabetes in Baghdad. Participant
Objectives: To document electromyographic changes in thyrotoxic patients, and to categorize the type of myopathic process in thyrotoxicosis.
Design: This case control study was designed to show the electromyographic changes in thyrotoxic patients and to compare these findings with that of normal aged matched controls to
show the significance of these changes in thyrotoxic patients. Student’s test was applied on the results and P value was extracted.
Subjects: Subjects in this study were chosen according to certain criteria depending mainly on their blood level of thyroid hormone (T3, and T4) and TSH. All of them are thyrotoxic patients, their ages range between 15 to 45 years. They were 25 patients (15
Background: Maxillary sinusitis is one of the most common infections of humans. Sinusitis can be defined as an inflammation of the membrane lining of any sinus, especially one of the
paranasal sinuses.
Objective: To determine the causative microorganisms of chronic maxillary sinusitis.
Patients: Forty five chronic sinusitis patients were involved in the present study.
Methods: Sampling method were sinus specimens (aspiration or injection aspiration).
Results: Haemophilus species, Streptococcus pneumoniae (S.pneumoniae) and Moraxella catarrhalis (M.catarrhalis) were the most frequent isolates; in addition Penicillium and
Cladosporium species were isolated from some chronic sinusitis patients.
Conclusion: Chr
Background: To elucidate distinctive CT imaging features that allows a diagnosis of hepatic hydatidosis.
Patients and methods : The computed tomographic (CT) findings of 58 patients with sonographically detected cystic liver lesions were prospectively analyzed. These patients were
followed up until a final diagnosis was reached.
Results : By CT scanning we correctly localized and diagnosed 81 hepatic hydatid cysts in 50 patients. These were all proved by surgery or endoscopic retrograde cholangio-pancreatography (ERCP). Stage III and II hydatid cysts were the commonest types (29 % and 25 % respectively ). 52 % of the cysts were 5-10 cm at presentation. At CT, we identified some ancillary imaging fea
Background: This study comprises two parts. "['his part deals with epidemiology, aetiology and clinical features of brain abscess during a 10 years period, while the second will deal
with diagnostic investigation, management and final outcome of brain abscess
Methods: The case records of patients with brain abscess admitted to the neurosurgical specialties hospital in Baghdad over a 10 years period extending from 1" Jan. 1993 to 31S`
Dec. 2002, inclusive were reviewed. Data obtained included demographic and clinical data.
Results: A total of 78 cases (1.2% of total admission) of brain abscess were admitted. Their age ranged from one month to 68 years. The most common' aetiological (actor was cyanotic
heart d
Background: pain is frequently listed among initial symptoms of MS or an occurring in the course of the disease.
Patients and Methods: one hundred thirty MS patients diagnosed according to Macdonald's criteria compared with 115 matched age and sex control were interviewed about pain Neuropathic, somatic and headache.
Results: Neuropathic pain was significantly higher in MS than control group, while LLD and ARP were of no significance difference between two groups. For somatic pain there was significant increase in MS.
Conclusion: pain is common in MS especially LLD. There is no significant difference between pain subtypes and duration of disease and FS, EDSS.
خلفية الدراسة: تستخدم الاسماك المعلبة في جميع انحاء العالم كوجبة غذائية مفضلة. ارتفاع مستويات وتراكيز عناصر الفلزات الثقيلة في الطبيعة قد يؤدي الى تلوث البيئة وبضمنها البيئة المائية الذي قد يسبب تهديدا للامن الغذائي وصحة افراد المجتمع. نتيجة لهذا التلوث فان عناصر الفلزات الثقيلة قد تتراكم في انسجة الاحياء المائية ومن ضمنها الاسماك التي تعتبر صنفا غذائيا رئيسيا للانسان.
... Show Moreالمقدمة:الإباضة هي الوظيفة الأساسية للمبيض وتوقف هذه الوظيفة هو أهم أسباب عدم الخصوبة في الإناث .تعتبر الأدوية الاستيرودية المضادة للألتهابات من أكثر الأدوية أستعمالاً وذلك لخواصها المسكنة للألم والخافضة للحرارة وكونها مضادة للألتهابات وقد ثبت أن هذه الأدوية تؤثر على الإباضة في اجناس كثيرة من اللبائن التي جربت عليها هذه الأدوية لحد الآن ومن المرجح ان السبب هو في تثبيط هذه الأ
... Show MoreBackground: Keloids of the ear present a significant clinical challenge, with surgical excision alone associated with high recurrence rates (45%–100%). Various adjuvant treatments have been explored to improve outcomes, with intra-lesional corticosteroids showing promise.
Objectives: To evaluate the effectiveness and safety of debulking combined with intralesional injection of triamcinolone acetonide versus debulking alone in treating earlobe and helical keloids.
Methods: This study was conducted at the Department of Dermatology and Venereology, Baghdad Teaching Hospital, from January 2014 to October 2015. Twenty-eight female patients with 67 keloid lesions resulting from
... Show MoreBackground: Infertility is a global issue that not only affects individuals but also impacts society as a whole. Kisspeptin has emerged as a key player in the understanding of certain facets of infertility. However, research on the role of kisspeptin in fertility, particularly in assisted reproductive treatment, remains limited.
Objectives: To investigate the potential association between follicular fluid kisspeptin levels and various reproductive parameters, including the number and maturity of oocytes, fertilization rate, pregnancy detection, anti-Müllerian hormone levels, and the age of females.
Methods: Sixty infertile couples with an age range of 20 – 40 years participa
Background: Substance abuse can be defined briefly as the excessive and continuous consumption of psychoactive substances without medical supervision, leading to dependence and adverse health consequences. Substance abuse is an escalating and surging public health challenge in Iraq.
Objectives: To assess the frequency of substance abuse among a large group of senior undergraduate medical students and to identify the associated factors.
Methods: A convenience sample of 388 senior medical students from the College of Medicine/ University of Baghdad during April 2023 took part in this study. Itemployed a modified electronic version of the Drug Addiction Survey Questionnaire (D
... Show MoreBackground: chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation and a range of pathological changes in the lung.
Background: rheumatoid arthritis (RA) is a systematic autoinmume disease with prevalence of 1% world wild, it is characterized by chronic inflammation of synovial joints, which commonly leads to progressive joints destruction and consequent disability with reduction in quality of life of life.
الخلفية: التصلب اللويحي واحد من الاضطرابات العصبية الواسع الانتشار بشكل متزايد. هناك دراسات للعوامل الوبائية والأسرية وتأثير العوامل الوراثية والبيئية في تحديد قابلية الاصابة بالمرض. هذه التاثيرات تم التحقق منها بدقة في دراستنا.
الأهداف: الهدف من هذه الدراسة مقارنة الخصائص الديموغرافية، والاعراض السريرية، ومسار المرض بين الحالات ذات التاريخ الأسري والمتفرقة من ال
... Show Moreتمهيد: دور الفيروس الحليمي البشري كمسبب لسرطان المبيض ظل غير واضح والنتائج متناقضة. عدة دراسات اثبتت وجود الفيروس في اورام المبيض الحميدة والخبيثة.
اهداف الدراسة: تحديد نسبة وجود الفيروس الحليمي البشري للانواع العالية الخطورة (16 و 18) والانواع الواطئة الخطورة (6 و 11) في سرطان الخلايا الطلائية السطحية للمبيض مقارنة بمجموعة الاورام الحميدة ومجموعة السيطرة.
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