Background: The materials and techniques of orthodontic bonding systems remain a pivotal concern in orthodontic research. This issue is further complicated by orthodontists' preferences. To assess the effect of knowledge and practice on the attitudes of orthodontists towards bonding materials and techniques. Methods: A cross-sectional, questionnaire-based study was conducted using Google Forms. The questionnaire comprised 17 multiple-choice questions that targeted orthodontists' awareness, knowledge, and attitude towards bonding materials. It was distributed via email or social networking platforms to specialist Iraqi orthodontists. Results: A total of 176 participants responded with nearly equal representation between the sexes. The majority of respondents (approximately 70%) held an M.Sc. degree, and slightly more than half the sample worked in both governmental and private clinics. All participants were aware of the etch and rinse adhesive system, and the majority used it with light curing as the activation method. The effect of academic degrees and place of work was evident in some responses related to the selection and management of bonding adhesive. Conclusions: The orthodontists preferred the traditional etch and rinse technique to minimise bracket loss and maintain treatment flow. The self-etch primer system was the preferred option when prioritising safety, time efficiency, reduced technique sensitivity, and aerosol reduction. Clinical choices may be significantly shaped by skills and information from initial training, despite the available evidence-base. Future decision-making should prioritise leveraging scientific evidence effectively.