In this study we synthesized the new compounds containing bis-1,3,4-thiadiazole
3(A-D)n through many eaction steps (cyclization, diazotiazation and etherification
respectively). The compounds have been characterized by melting point, FTIR and
1HNMR data. All the synthesized compounds have been evaluated in vitro for their
antimicrobial activities against several microbes like: Escherichia coli, Klebsiellia
pneumonia, Pseudomonas aerugenosa, Serratia marscens and Staphylococcus aureus
and the results showed that some of these compounds have very good antibacterial
activity.